| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10001070 | HBV | ENSG00000171873.8 | protein_coding | ADRA1D | No | No | 146 | B0ZBE0 P25100 |
| TVIS10024274 | HBV | ENSG00000171873.8 | protein_coding | ADRA1D | No | No | 146 | B0ZBE0 P25100 |
| TVIS10028961 | HBV | ENSG00000171873.8 | protein_coding | ADRA1D | No | No | 146 | B0ZBE0 P25100 |
| TVIS30018439 | HIV | ENSG00000171873.8 | protein_coding | ADRA1D | No | No | 146 | B0ZBE0 P25100 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | ADRA1D |
|---|---|
| DrugBank ID | DB00706 |
| Drug Name | Tamsulosin |
| Target ID | BE0000715 |
| UniProt ID | P25100 |
| Regulation Type | antagonist |
| PubMed IDs | 11752352; 9117115; 16986050; 16518087; 12270758; 8996174; 14680444 |
| Citations | Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5.@@Noble AJ, Chess-Williams R, Couldwell C, Furukawa K, Uchyiuma T, Korstanje C, Chapple CR: The effects of tamsulosin, a high affinity antagonist at functional alpha 1A- and alpha 1D-adrenoceptor subtypes. Br J Pharmacol. 1997 Jan;120(2):231-8.@@Lowe FC: Summary of clinical experiences with tamsulosin for the treatment of benign prostatic hyperplasia. Rev Urol. 2005;7 Suppl 4:S13-21.@@Tomiyama Y, Tatemichi S, Tadachi M, Kobayashi S, Hayashi M, Kobayashi M, Yamazaki Y, Shibata N: [Effect of silodosin on intraurethral pressure increase induced by hypogastric nerve stimulation in dogs with benign prostatic hyperplasia]. Yakugaku Zasshi. 2006 Mar;126 Spec no.:225-30.@@Ishiguro M, Futabayashi Y, Ohnuki T, Ahmed M, Muramatsu I, Nagatomo T: Identification of binding sites of prazosin, tamsulosin and KMD-3213 with alpha(1)-adrenergic receptor subtypes by molecular modeling. Life Sci. 2002 Oct 11;71(21):2531-41.@@Taguchi K, Saitoh M, Sato S, Asano M, Michel MC: Effects of tamsulosin metabolites at alpha-1 adrenoceptor subtypes. J Pharmacol Exp Ther. 1997 Jan;280(1):1-5.@@Michel MC, de la Rosette JJ: Efficacy and safety of tamsulosin in the treatment of urological diseases. Expert Opin Pharmacother. 2004 Jan;5(1):151-60. |
| Groups | Approved; Investigational |
| Direct Classification | Amphetamines and derivatives |
| SMILES | CCOC1=CC=CC=C1OCCN[C@H](C)CC1=CC(=C(OC)C=C1)S(N)(=O)=O |
| Pathways | |
| PharmGKB | PA451583 |
| ChEMBL | CHEMBL836 |
