Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS10001070HBVENSG00000171873.8protein_codingADRA1DNoNo146B0ZBE0
P25100
TVIS10024274HBVENSG00000171873.8protein_codingADRA1DNoNo146B0ZBE0
P25100
TVIS10028961HBVENSG00000171873.8protein_codingADRA1DNoNo146B0ZBE0
P25100
TVIS30018439HIVENSG00000171873.8protein_codingADRA1DNoNo146B0ZBE0
P25100
TCGA Plot Options
Drug Information
GeneADRA1D
DrugBank IDDB06262
Drug NameDroxidopa
Target IDBE0000715
UniProt IDP25100
Regulation Typeagonist
PubMed IDs17266602; 20412040; 7582530; 7674815
CitationsBishop MJ: Recent advances in the discovery of alpha1-adrenoceptor agonists. Curr Top Med Chem. 2007;7(2):135-45.@@Du L, Li M: Modeling the interactions between alpha(1)-adrenergic receptors and their antagonists. Curr Comput Aided Drug Des. 2010 Sep;6(3):165-78.@@Kenny BA, Chalmers DH, Philpott PC, Naylor AM: Characterization of an alpha 1D-adrenoceptor mediating the contractile response of rat aorta to noradrenaline. Br J Pharmacol. 1995 Jul;115(6):981-6.@@Testa R, Destefani C, Guarneri L, Poggesi E, Simonazzi I, Taddei C, Leonardi A: The alpha 1d-adrenoceptor subtype is involved in the noradrenaline-induced contractions of rat aorta. Life Sci. 1995;57(13):PL159-63.
GroupsApproved; Investigational
Direct ClassificationTyrosine and derivatives
SMILESN[C@@H]([C@H](O)C1=CC(O)=C(O)C=C1)C(O)=O
Pathways
PharmGKBPA164748386
ChEMBLCHEMBL2103827