| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10001070 | HBV | ENSG00000171873.8 | protein_coding | ADRA1D | No | No | 146 | B0ZBE0 P25100 |
| TVIS10024274 | HBV | ENSG00000171873.8 | protein_coding | ADRA1D | No | No | 146 | B0ZBE0 P25100 |
| TVIS10028961 | HBV | ENSG00000171873.8 | protein_coding | ADRA1D | No | No | 146 | B0ZBE0 P25100 |
| TVIS30018439 | HIV | ENSG00000171873.8 | protein_coding | ADRA1D | No | No | 146 | B0ZBE0 P25100 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | ADRA1D |
|---|---|
| DrugBank ID | DB01136 |
| Drug Name | Carvedilol |
| Target ID | BE0000715 |
| UniProt ID | P25100 |
| Regulation Type | antagonist |
| PubMed IDs | 15306222; 18657662 |
| Citations | Koshimizu TA, Tsujimoto G, Hirasawa A, Kitagawa Y, Tanoue A: Carvedilol selectively inhibits oscillatory intracellular calcium changes evoked by human alpha1D- and alpha1B-adrenergic receptors. Cardiovasc Res. 2004 Sep 1;63(4):662-72.@@Van Tassell BW, Rondina MT, Huggins F, Gilbert EM, Munger MA: Carvedilol increases blood pressure response to phenylephrine infusion in heart failure subjects with systolic dysfunction: evidence of improved vascular alpha1-adrenoreceptor signal transduction. Am Heart J. 2008 Aug;156(2):315-21. doi: 10.1016/j.ahj.2008.04.004. Epub 2008 Jun 20. |
| Groups | Approved; Investigational |
| Direct Classification | Carbazoles |
| SMILES | COC1=CC=CC=C1OCCNCC(O)COC1=CC=CC2=C1C1=CC=CC=C1N2 |
| Pathways | Carvedilol Action Pathway |
| PharmGKB | PA448817 |
| ChEMBL | CHEMBL723 |
