| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10001070 | HBV | ENSG00000171873.8 | protein_coding | ADRA1D | No | No | 146 | B0ZBE0 P25100 |
| TVIS10024274 | HBV | ENSG00000171873.8 | protein_coding | ADRA1D | No | No | 146 | B0ZBE0 P25100 |
| TVIS10028961 | HBV | ENSG00000171873.8 | protein_coding | ADRA1D | No | No | 146 | B0ZBE0 P25100 |
| TVIS30018439 | HIV | ENSG00000171873.8 | protein_coding | ADRA1D | No | No | 146 | B0ZBE0 P25100 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | ADRA1D |
|---|---|
| DrugBank ID | DB00368 |
| Drug Name | Norepinephrine |
| Target ID | BE0000715 |
| UniProt ID | P25100 |
| Regulation Type | agonist |
| PubMed IDs | 17139284; 17016423; 15451776; 7582530; 7674815; 17266602; 18064417 |
| Citations | Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.@@Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34.@@Cleary L, Slattery J, Bexis S, Docherty JR: Sympathectomy reveals alpha 1A- and alpha 1D-adrenoceptor components to contractions to noradrenaline in rat vas deferens. Br J Pharmacol. 2004 Nov;143(6):745-52. Epub 2004 Sep 27.@@Kenny BA, Chalmers DH, Philpott PC, Naylor AM: Characterization of an alpha 1D-adrenoceptor mediating the contractile response of rat aorta to noradrenaline. Br J Pharmacol. 1995 Jul;115(6):981-6.@@Testa R, Destefani C, Guarneri L, Poggesi E, Simonazzi I, Taddei C, Leonardi A: The alpha 1d-adrenoceptor subtype is involved in the noradrenaline-induced contractions of rat aorta. Life Sci. 1995;57(13):PL159-63.@@Bishop MJ: Recent advances in the discovery of alpha1-adrenoceptor agonists. Curr Top Med Chem. 2007;7(2):135-45.@@Gilsbach R, Hein L: Presynaptic metabotropic receptors for acetylcholine and adrenaline/noradrenaline. Handb Exp Pharmacol. 2008;(184):261-88. |
| Groups | Approved |
| Direct Classification | Catechols |
| SMILES | NC[C@H](O)C1=CC(O)=C(O)C=C1 |
| Pathways | Remifentanil Action Pathway; Hydrocodone Action Pathway; Sufentanil Action Pathway; Fluoxetine Action Pathway; Morphine Action Pathway; 3-Methylthiofentanyl Action Pathway; Benzocaine Action Pathway; Oxybuprocaine Action Pathway; Codeine Action Pathway; Alkaptonuria; Tyrosine Hydroxylase Deficiency; Ketobemidone Action Pathway; Propoxyphene Action Pathway; Dihydromorphine Action Pathway; Nicotine Action Pathway; Proparacaine Action Pathway; Methadyl Acetate Action Pathway; Hawkinsinuria; Oxymorphone Action Pathway; Dimethylthiambutene Action Pathway; Fentanyl Action Pathway; Dopamine beta-Hydroxylase Deficiency; Lidocaine (Local Anaesthetic) Action Pathway; Monoamine Oxidase-A Deficiency (MAO-A); Aromatic L-Aminoacid Decarboxylase Deficiency; Hydromorphone Action Pathway; Tyrosinemia, Transient, of the Newborn; Anileridine Action Pathway; Bupivacaine Action Pathway; Levallorphan Action Pathway |
| PharmGKB | PA450649 |
| ChEMBL | CHEMBL1437 |
