| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10001070 | HBV | ENSG00000171873.8 | protein_coding | ADRA1D | No | No | 146 | B0ZBE0 P25100 |
| TVIS10024274 | HBV | ENSG00000171873.8 | protein_coding | ADRA1D | No | No | 146 | B0ZBE0 P25100 |
| TVIS10028961 | HBV | ENSG00000171873.8 | protein_coding | ADRA1D | No | No | 146 | B0ZBE0 P25100 |
| TVIS30018439 | HIV | ENSG00000171873.8 | protein_coding | ADRA1D | No | No | 146 | B0ZBE0 P25100 |
Target Gene Table
▼
TCGA Plot Options
▼
Drug Information
▼
| Gene | ADRA1D |
|---|---|
| DrugBank ID | DB01142 |
| Drug Name | Doxepin |
| Target ID | BE0000715 |
| UniProt ID | P25100 |
| Regulation Type | antagonist |
| PubMed IDs | 7855217; 19179941; 6086881 |
| Citations | Cusack B, Nelson A, Richelson E: Binding of antidepressants to human brain receptors: focus on newer generation compounds. Psychopharmacology (Berl). 1994 May;114(4):559-65.@@Stahl SM: Selective histamine H1 antagonism: novel hypnotic and pharmacologic actions challenge classical notions of antihistamines. CNS Spectr. 2008 Dec;13(12):1027-38.@@Richelson E, Nelson A: Antagonism by antidepressants of neurotransmitter receptors of normal human brain in vitro. J Pharmacol Exp Ther. 1984 Jul;230(1):94-102. |
| Groups | Approved; Investigational |
| Direct Classification | Dibenzoxepines |
| SMILES | [H]C(CCN(C)C)=C1C2=CC=CC=C2COC2=CC=CC=C12 |
| Pathways | Doxepin Metabolism Pathway; Doxepin H1-Antihistamine Action |
| PharmGKB | PA449409 |
| ChEMBL | CHEMBL1628227 |
