Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS10001070HBVENSG00000171873.8protein_codingADRA1DNoNo146B0ZBE0
P25100
TVIS10024274HBVENSG00000171873.8protein_codingADRA1DNoNo146B0ZBE0
P25100
TVIS10028961HBVENSG00000171873.8protein_codingADRA1DNoNo146B0ZBE0
P25100
TVIS30018439HIVENSG00000171873.8protein_codingADRA1DNoNo146B0ZBE0
P25100
TCGA Plot Options
Drug Information
GeneADRA1D
DrugBank IDDB00321
Drug NameAmitriptyline
Target IDBE0000715
UniProt IDP25100
Regulation Typeantagonist
PubMed IDs20363235
CitationsNojimoto FD, Mueller A, Hebeler-Barbosa F, Akinaga J, Lima V, Kiguti LR, Pupo AS: The tricyclic antidepressants amitriptyline, nortriptyline and imipramine are weak antagonists of human and rat alpha1B-adrenoceptors. Neuropharmacology. 2010 Jul-Aug;59(1-2):49-57. doi: 10.1016/j.neuropharm.2010.03.015. Epub 2010 Apr 2.
GroupsApproved
Direct ClassificationDibenzocycloheptenes
SMILESCN(C)CCC=C1C2=CC=CC=C2CCC2=CC=CC=C12
Pathways
PharmGKBPA448385
ChEMBLCHEMBL629