| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS44010428 | HTLV-1 | ENSG00000166736.12 | protein_coding | HTR3A | No | No | 3359 | P46098 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | HTR3A |
|---|---|
| DrugBank ID | DB01156 |
| Drug Name | Bupropion |
| Target ID | BE0000311 |
| UniProt ID | P46098 |
| Regulation Type | negative modulator |
| PubMed IDs | 27671323 |
| Citations | Pandhare A, Pappu AS, Wilms H, Blanton MP, Jansen M: The antidepressant bupropion is a negative allosteric modulator of serotonin type 3A receptors. Neuropharmacology. 2017 Feb;113(Pt A):89-99. doi: 10.1016/j.neuropharm.2016.09.021. Epub 2016 Sep 24. |
| Groups | Approved |
| Direct Classification | Alkyl-phenylketones |
| SMILES | CC(NC(C)(C)C)C(=O)C1=CC(Cl)=CC=C1 |
| Pathways | |
| PharmGKB | PA448687 |
| ChEMBL | CHEMBL894 |
