Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS44010428HTLV-1ENSG00000166736.12protein_codingHTR3ANoNo3359P46098
TCGA Plot Options
Drug Information
GeneHTR3A
DrugBank IDDB01233
Drug NameMetoclopramide
Target IDBE0000311
UniProt IDP46098
Regulation Typeantagonist
PubMed IDs2955843; 21278804
CitationsCostall B, Gunning SJ, Naylor RJ, Tyers MB: The effect of GR38032F, novel 5-HT3-receptor antagonist on gastric emptying in the guinea-pig. Br J Pharmacol. 1987 Jun;91(2):263-4.@@Lee A, Kuo B: Metoclopramide in the treatment of diabetic gastroparesis. Expert Rev Endocrinol Metab. 2010;5(5):653-662.
GroupsApproved; Investigational
Direct ClassificationAminophenyl ethers
SMILESCCN(CC)CCNC(=O)C1=CC(Cl)=C(N)C=C1OC
Pathways
PharmGKBPA450475
ChEMBLCHEMBL86