Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS44047170HTLV-1ENSG00000140009.19protein_codingESR2NoNo2100Q92731
TCGA Plot Options
Drug Information
GeneESR2
DrugBank IDDB04468
Drug NameAfimoxifene
Target IDBE0000792
UniProt IDQ92731
Regulation Type
PubMed IDs15846122
CitationsReed CA, Berndtson AK, Nephew KP: Dose-dependent effects of 4-hydroxytamoxifen, the active metabolite of tamoxifen, on estrogen receptor-alpha expression in the rat uterus. Anticancer Drugs. 2005 Jun;16(5):559-67.
GroupsInvestigational
Direct ClassificationStilbenes
SMILESCCC(=C(/C1=CC=C(O)C=C1)C1=CC=C(OCCN(C)C)C=C1)C1=CC=CC=C1
Pathways
PharmGKB
ChEMBLCHEMBL489