Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS44047170HTLV-1ENSG00000140009.19protein_codingESR2NoNo2100Q92731
TCGA Plot Options
Drug Information
GeneESR2
DrugBank IDDB04574
Drug NameEstrone sulfate
Target IDBE0000792
UniProt IDQ92731
Regulation Typeagonist
PubMed IDs17464340; 2011412
CitationsVijayanathan V, Greenfield NJ, Thomas TJ, Ivanova MM, Tyulmenkov VV, Klinge CM, Gallo MA, Thomas T: Effects of estradiol and 4-hydroxytamoxifen on the conformation, thermal stability, and DNA recognition of estrogen receptor beta. Biochem Cell Biol. 2007 Feb;85(1):1-10.@@Sasson S: Equilibrium binding analysis of estrogen agonists and antagonists: relation to the activation of the estrogen receptor. Pathol Biol (Paris). 1991 Jan;39(1):59-69.
GroupsApproved
Direct ClassificationSulfated steroids
SMILES[H][C@@]12CCC(=O)[C@@]1(C)CC[C@]1([H])C3=C(CC[C@@]21[H])C=C(OS(O)(=O)=O)C=C3
PathwaysSulfite Oxidase Deficiency; Estrone Metabolism; Aromatase Deficiency; 17-beta Hydroxysteroid Dehydrogenase III Deficiency; Androgen and Estrogen Metabolism; Sulfate/Sulfite Metabolism
PharmGKBPA165958342
ChEMBLCHEMBL494753