Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS44047170HTLV-1ENSG00000140009.19protein_codingESR2NoNo2100Q92731
TCGA Plot Options
Drug Information
GeneESR2
DrugBank IDDB00655
Drug NameEstrone
Target IDBE0000792
UniProt IDQ92731
Regulation Type
PubMed IDs11518614; 19913605
CitationsGutendorf B, Westendorf J: Comparison of an array of in vitro assays for the assessment of the estrogenic potential of natural and synthetic estrogens, phytoestrogens and xenoestrogens. Toxicology. 2001 Sep 14;166(1-2):79-89.@@Dang Z: Comparison of relative binding affinities to fish and mammalian estrogen receptors: the regulatory implications. Toxicol Lett. 2010 Feb 15;192(3):298-315. doi: 10.1016/j.toxlet.2009.11.004. Epub 2009 Nov 12.
GroupsApproved
Direct ClassificationEstrogens and derivatives
SMILES[H][C@@]12CCC(=O)[C@@]1(C)CC[C@]1([H])C3=C(CC[C@@]21[H])C=C(O)C=C3
PathwaysAndrostenedione Metabolism; Sulfite Oxidase Deficiency; Estrone Metabolism; Aromatase Deficiency; 17-beta Hydroxysteroid Dehydrogenase III Deficiency; Androgen and Estrogen Metabolism; Sulfate/Sulfite Metabolism
PharmGKBPA449512
ChEMBLCHEMBL1405