Gene: ZFHX4-AS1

100192378
-
ZFHX4 antisense RNA 1
ncRNA
8q21.13
Ensembl:ENSG00000253661
NC_000008.11
SNP Mapped
2   ANCO-SNPs
ND
0   
NA (AD)  NA (ND)   (Frontal_Cortex)
4.153e-1 (AD)  6.531e-2 (ND)

ANCO-SNPs

SNP ID Position Alleles Trait Variation Type
rs16939329chr8:76651943 (GRCh38.p7)G>A / G>Cnicotine dependenceSNV(Single Nucleotide Variation)
rs10504631chr8:76626252 (GRCh38.p7)A>Gnicotine dependenceSNV(Single Nucleotide Variation)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
DDO0.792
ACAA20.791
NPAS30.791
ETNPPL0.789
HSDL20.782
ZFHX40.766
HOGA10.764
PRTFDC10.758
ALDH7A10.757
DECR10.756

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
CACNA1F-0.516
AGMAT-0.486
OSBPL10-0.483
OPRD1-0.48
FHL2-0.479
KCNK9-0.479
TRABD2A-0.475
SLC36A1-0.474
TNFAIP8L1-0.473
MCHR1-0.47

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ZFHX4-AS1 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ZFHX4-AS1 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ZFHX4-AS1 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ZFHX4-AS1 mRNA"27188386
D016604Aflatoxin B1Aflatoxin B1 results in decreased methylation of ZFHX4-AS1 gene27153756
D018501Antirheumatic AgentsAntirheumatic Agents results in increased expression of ZFHX4-AS1 mRNA24449571
C487081belinostatbelinostat results in increased expression of ZFHX4-AS1 mRNA26272509
C004925methylmercuric chloridemethylmercuric chloride results in decreased expression of ZFHX4-AS1 mRNA28001369
C496932panobinostatpanobinostat results in increased expression of ZFHX4-AS1 mRNA26272509
D010662Phenylmercuric Acetate"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ZFHX4-AS1 mRNA"27188386
D014635Valproic Acid"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ZFHX4-AS1 mRNA"27188386
D014635Valproic AcidValproic Acid results in decreased expression of ZFHX4-AS1 mRNA26272509|2800136
D014635Valproic AcidValproic Acid results in increased expression of ZFHX4-AS1 mRNA24935251

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO ID GO Term Qualifier Evidence PubMed
GO ID GO Term Qualifier Evidence PubMed
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

There is no Interaction data for this gene.

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal