Gene: LHFPL6

10186
LHFP
LHFPL tetraspan subfamily member 6
protein-coding
13q13.3-q14.11
Ensembl:ENSG00000183722 MIM:606710 Vega:OTTHUMG00000016767 UniprotKB:Q9Y693
NC_000013.11
SNP Mapped
2   ANCO-SNPs
AD
0   
NA (AD)  NA (ND)   (Frontal_Cortex)
9.722e-2 (AD)  2.066e-1 (ND)

ANCO-SNPs

SNP ID Position Alleles Trait Variation Type
rs7317775chr13:39440781 (GRCh38.p7)T>Aalcohol dependenceSNV(Single Nucleotide Variation)
rs9594332chr13:39434823 (GRCh38.p7)G>Aalcohol dependenceSNV(Single Nucleotide Variation)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with entinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of LHFPL6 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of LHFPL6 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with panobinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of LHFPL6 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of LHFPL6 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of LHFPL6 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of LHFPL6 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with entinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of LHFPL6 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of LHFPL6 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with panobinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of LHFPL6 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of LHFPL6 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of LHFPL6 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of LHFPL6 mRNA"27188386
D000082AcetaminophenAcetaminophen results in decreased expression of LHFPL6 mRNA22230336
D000447AldehydesAldehydes results in increased expression of LHFPL6 mRNA25014914
C006632arsenic trioxidearsenic trioxide results in decreased expression of LHFPL6 mRNA15070760|1576101
D0151237,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide"7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased expression of LHFPL6 mRNA"20382639
C038328BEP protocolBEP protocol results in increased expression of LHFPL6 mRNA18987330
C006780bisphenol Abisphenol A affects the expression of LHFPL6 mRNA25181051
C018475butyraldehydebutyraldehyde results in increased expression of LHFPL6 mRNA26079696
C584509C646 compoundC646 compound results in decreased expression of LHFPL6 mRNA26191083
D002104CadmiumCadmium results in decreased expression of LHFPL6 mRNA24376830
D002220CarbamazepineCarbamazepine affects the expression of LHFPL6 mRNA25979313
C012843cinnamic aldehydecinnamic aldehyde results in increased expression of LHFPL6 mRNA19524605
C018021cobaltous chloridecobaltous chloride results in decreased expression of LHFPL6 mRNA19320972
D003300Copper[NSC 689534 binds to Copper] which results in increased expression of LHFPL6 mRNA20971185
D016572CyclosporineCyclosporine results in increased expression of LHFPL6 mRNA20106945
C089595cylindrospermopsincylindrospermopsin results in increased expression of LHFPL6 mRNA24921660
D003561CytarabineCytarabine results in increased expression of LHFPL6 mRNA21198554
C010902decabromobiphenyl etherdecabromobiphenyl ether results in decreased expression of LHFPL6 mRNA23640034
D002945Cisplatin[Cisplatin co-treated with jinfukang] results in decreased expression of LHFPL6 mRNA27392435
D002945CisplatinCisplatin results in decreased expression of LHFPL6 mRNA19561079
D004147DioxinsDioxins affects the expression of LHFPL6 mRNA20463971
D004237DiuronDiuron results in decreased expression of LHFPL6 mRNA25152437
D004237DiuronDiuron results in increased expression of LHFPL6 mRNA21551480
C118739entinostatentinostat results in increased expression of LHFPL6 mRNA26272509
C118739entinostat"[NOG protein co-treated with entinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of LHFPL6 mRNA"27188386
C045651epigallocatechin gallate[potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of LHFPL6 mRNA22079256
D005485FlutamideFlutamide results in decreased expression of LHFPL6 mRNA24136188
D004397FonofosFonofos results in increased methylation of LHFPL6 promoter22847954
C069837fullerene C60fullerene C60 results in decreased expression of LHFPL6 mRNA19167457
D006861Hydrogen Peroxide[Hydrogen Peroxide co-treated with Theophylline] results in increased expression of LHFPL6 protein18951874
D007213IndomethacinIndomethacin results in decreased expression of LHFPL6 mRNA28201806
D015759Ionomycin[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of LHFPL6 mRNA25613284
C544151jinfukang[Cisplatin co-treated with jinfukang] results in decreased expression of LHFPL6 mRNA27392435
D008070LipopolysaccharidesLipopolysaccharides results in decreased expression of LHFPL6 mRNA25613284
C042720mercuric bromidemercuric bromide results in increased expression of LHFPL6 mRNA26272509
C042720mercuric bromide"[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of LHFPL6 mRNA"27188386
C004925methylmercuric chloridemethylmercuric chloride results in increased expression of LHFPL6 mRNA23179753|2718838
D008741Methyl MethanesulfonateMethyl Methanesulfonate results in decreased expression of LHFPL6 mRNA26011545
D0156551-Methyl-4-phenylpyridinium1-Methyl-4-phenylpyridinium results in decreased expression of LHFPL6 mRNA24810058
C028007nickel monoxidenickel monoxide results in decreased expression of LHFPL6 mRNA19167457
C558013NSC 689534[NSC 689534 binds to Copper] which results in increased expression of LHFPL6 mRNA20971185
C030110oxaliplatin[oxaliplatin co-treated with Topotecan] results in increased expression of LHFPL6 mRNA25729387
C030110oxaliplatinoxaliplatin results in increased expression of LHFPL6 mRNA25729387
C496932panobinostat"[NOG protein co-treated with panobinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of LHFPL6 mRNA"27188386
C496932panobinostatpanobinostat results in increased expression of LHFPL6 mRNA26272509
D010278ParathionParathion results in increased methylation of LHFPL6 promoter22847954
C046012pentanalpentanal results in increased expression of LHFPL6 mRNA26079696
D010662Phenylmercuric Acetate"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of LHFPL6 mRNA"27188386
D010662Phenylmercuric AcetatePhenylmercuric Acetate results in increased expression of LHFPL6 mRNA26272509
C027373potassium chromate(VI)[potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of LHFPL6 mRNA22079256
C027373potassium chromate(VI)potassium chromate(VI) results in decreased expression of LHFPL6 mRNA22079256|2271453
D011374ProgesteroneProgesterone results in increased expression of LHFPL6 mRNA20864642|2154024
C005556propionaldehydepropionaldehyde results in increased expression of LHFPL6 mRNA26079696
D011441PropylthiouracilPropylthiouracil results in decreased expression of LHFPL6 mRNA24780913
D015474IsotretinoinIsotretinoin results in increased expression of LHFPL6 mRNA20436886
D012822Silicon DioxideSilicon Dioxide analog results in increased expression of LHFPL6 mRNA25895662
D012822Silicon DioxideSilicon Dioxide results in increased expression of LHFPL6 mRNA25351596
D012999SomanSoman results in increased expression of LHFPL6 mRNA19281266
C012568terbufosterbufos results in increased methylation of LHFPL6 promoter22847954
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of LHFPL6 mRNA22298810
D013755Tetradecanoylphorbol Acetate[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of LHFPL6 mRNA25613284
D019284ThapsigarginThapsigargin results in increased expression of LHFPL6 mRNA22378314
D013806Theophylline[Hydrogen Peroxide co-treated with Theophylline] results in increased expression of LHFPL6 protein18951874
D013806TheophyllineTheophylline results in decreased expression of LHFPL6 mRNA18951874
D013893ThiramThiram results in increased expression of LHFPL6 mRNA20530235
D019772Topotecan[oxaliplatin co-treated with Topotecan] results in increased expression of LHFPL6 mRNA25729387
D019772TopotecanTopotecan results in increased expression of LHFPL6 mRNA25729387
C012589trichostatin A"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of LHFPL6 mRNA"27188386
C012589trichostatin Atrichostatin A results in increased expression of LHFPL6 mRNA24935251|2627250
D014635Valproic Acid"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of LHFPL6 mRNA"27188386
D014635Valproic AcidValproic Acid affects the expression of LHFPL6 mRNA25979313
D014635Valproic AcidValproic Acid results in increased expression of LHFPL6 mRNA19101580|2317975
D014638VanadatesVanadates results in increased expression of LHFPL6 mRNA22714537
C025643vinclozolinvinclozolin results in decreased expression of LHFPL6 mRNA23034163
C111237vorinostatvorinostat results in increased expression of LHFPL6 mRNA26272509
C088658zoledronic acidzoledronic acid results in increased expression of LHFPL6 mRNA24714768

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO ID GO Term Qualifier Evidence PubMed
GO ID GO Term Qualifier Evidence PubMed
GO:0016021integral component of membrane-IEA-  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal