Gene: CNBD1

168975
-
cyclic nucleotide binding domain containing 1
protein-coding
8q21.3
Ensembl:ENSG00000176571 Vega:OTTHUMG00000163743 UniprotKB:Q8NA66
NC_000008.11
SNP Mapped
4   ANCO-SNPs
AD
0   
NA (AD)  NA (ND)   (Frontal_Cortex)
3.711e-1 (AD)  6.058e-1 (ND)

ANCO-SNPs

SNP ID Position Alleles Trait Variation Type
rs7833568chr8:87249563 (GRCh38.p7)T>A / T>Calcohol dependenceSNV(Single Nucleotide Variation)
rs2336981chr8:87243736 (GRCh38.p7)G>Aalcohol dependenceSNV(Single Nucleotide Variation)
rs719779chr8:87113490 (GRCh38.p7)T>Calcohol dependenceSNV(Single Nucleotide Variation)
rs4526378chr8:86922204 (GRCh38.p7)G>Talcohol dependenceSNV(Single Nucleotide Variation)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
HTN10.927
TAAR20.912
OR12D20.912
OR10W10.906
OR4A150.906
OR4C120.902
KRTAP6-20.902
OR5T20.902
CDY2A0.902
OR5M10.902

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
FUT9-0.286
SLC1A4-0.282
TMEM221-0.274
NOG-0.272
ADCY2-0.269
MMP15-0.264
B3GALT1-0.263
DBP-0.259
CORO2B-0.258
PURG-0.258

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C006780bisphenol Abisphenol A results in increased expression of CNBD1 mRNA29275510
C006780bisphenol Abisphenol A results in decreased expression of CNBD1 mRNA25181051
D002392Catechin[Catechin co-treated with Grape Seed Proanthocyanidins] results in decreased expression of CNBD1 mRNA24763279
C511402Grape Seed Proanthocyanidins[Catechin co-treated with Grape Seed Proanthocyanidins] results in decreased expression of CNBD1 mRNA24763279
D014635Valproic AcidValproic Acid results in decreased methylation of CNBD1 gene29154799

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO ID GO Term Qualifier Evidence PubMed
GO ID GO Term Qualifier Evidence PubMed
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal