Gene: CEP83

51134
CCDC41|NPHP18|NY-REN-58
centrosomal protein 83
protein-coding
12q22
Ensembl:ENSG00000173588 MIM:615847 Vega:OTTHUMG00000170242 UniprotKB:Q9Y592
NG_051825.1
SNP Mapped
3   ANCO-SNPs
AD
0   
NA (AD)  NA (ND)   (Frontal_Cortex)
6.297e-1 (AD)  5.621e-1 (ND)

ANCO-SNPs

SNP ID Position Alleles Trait Variation Type
rs7138291chr12:94347930 (GRCh38.p7)T>Calcohol dependenceSNV(Single Nucleotide Variation)
rs4761605chr12:94335801 (GRCh38.p7)C>Talcohol dependenceSNV(Single Nucleotide Variation)
rs4761601chr12:94278226 (GRCh38.p7)G>Aalcohol dependenceSNV(Single Nucleotide Variation)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C02017516 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione"16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione results in decreased expression of CEP83 mRNA"20519331
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of CEP83 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of CEP83 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of CEP83 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of CEP83 mRNA"27188386
D000082AcetaminophenAcetaminophen affects the expression of CEP83 mRNA17562736
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of CEP83 mRNA20106945|2163298
D002104CadmiumCadmium results in increased expression of CEP83 mRNA24067728
D002251Carbon TetrachlorideCarbon Tetrachloride results in increased expression of CEP83 mRNA27339419
D020245p-Chloromercuribenzoic Acid"[NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of CEP83 mRNA"27188386
D020245p-Chloromercuribenzoic Acidp-Chloromercuribenzoic Acid results in decreased expression of CEP83 mRNA26272509
D019327Copper SulfateCopper Sulfate results in decreased expression of CEP83 mRNA19549813
C015835dimethyl-4-toluidinedimethyl-4-toluidine results in decreased expression of CEP83 mRNA27638505
C045651epigallocatechin gallate[potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of CEP83 mRNA22079256
D004997Ethinyl EstradiolEthinyl Estradiol affects the expression of CEP83 mRNA17555576
D004997Ethinyl EstradiolEthinyl Estradiol results in decreased expression of CEP83 mRNA29097150
C000499ferric oxideferric oxide analog results in decreased expression of CEP83 mRNA24525745
C043562flavoneflavone results in increased expression of CEP83 protein14750173
C004312glycidolglycidol results in decreased expression of CEP83 mRNA24915197
D017313FenretinideFenretinide results in increased expression of CEP83 mRNA28973697
C492448ICG 001ICG 001 results in increased expression of CEP83 mRNA26191083
C016517indole-3-carbinolindole-3-carbinol affects the expression of CEP83 mRNA21396975
C002385linsidominelinsidomine results in increased oxidation of CEP83 protein28086193
D058185Magnetite NanoparticlesMagnetite Nanoparticles results in decreased expression of CEP83 mRNA24525745
C004925methylmercuric chloridemethylmercuric chloride results in decreased expression of CEP83 mRNA28001369
D008741Methyl MethanesulfonateMethyl Methanesulfonate results in increased expression of CEP83 mRNA23649840
D009020MorphineMorphine results in increased expression of CEP83 mRNA20144693
C030110oxaliplatin[oxaliplatin co-treated with Topotecan] results in decreased expression of CEP83 mRNA25729387
C086401pentabromodiphenyl etherpentabromodiphenyl ether analog results in increased expression of CEP83 mRNA19095052
C076994perfluorooctane sulfonic acidperfluorooctane sulfonic acid results in decreased expression of CEP83 mRNA27153767
D010662Phenylmercuric Acetate"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of CEP83 mRNA"27188386
C006253pirinixic acid[pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of CEP83 mRNA19710929
D010936Plant ExtractsPlant Extracts results in increased expression of CEP83 mRNA23557933
C027373potassium chromate(VI)[potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of CEP83 mRNA22079256
C027373potassium chromate(VI)potassium chromate(VI) results in decreased expression of CEP83 mRNA22079256
D011794QuercetinQuercetin results in decreased expression of CEP83 mRNA21632981
D013629TamoxifenTamoxifen affects the expression of CEP83 mRNA17555576
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of CEP83 mRNA20106945|2163298
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of CEP83 mRNA21570461|2637764
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of CEP83 mRNA21215274
D019772Topotecan[oxaliplatin co-treated with Topotecan] results in decreased expression of CEP83 mRNA25729387
C015559trimellitic anhydridetrimellitic anhydride results in increased expression of CEP83 mRNA19042947
C406224valdecoxibvaldecoxib results in increased expression of CEP83 mRNA24136188
D014635Valproic AcidValproic Acid results in decreased expression of CEP83 mRNA23179753
D014635Valproic AcidValproic Acid results in decreased methylation of CEP83 gene29154799
C029297vinylidene chloridevinylidene chloride results in increased expression of CEP83 mRNA26682919

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0003674molecular_function-ND-  
GO:0005515protein binding-IPI23530209  
GO ID GO Term Qualifier Evidence PubMed
GO:0048278vesicle docking-IMP23530209  
GO:0060271cilium assembly-IMP23348840  23530209  
GO:0071539protein localization to centrosome-IMP23348840  23530209  
GO:0097711ciliary basal body-plasma membrane docking-TAS-  
GO ID GO Term Qualifier Evidence PubMed
GO:0005794Golgi apparatus-IDA23530209  
GO:0005814centriole-IDA23348840  23530209  
GO:0005829cytosol-TAS-  
GO:0097539ciliary transition fiber-IDA23348840  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence
R-HSA-1852241Organelle biogenesis and maintenanceTAS
R-HSA-5617833Cilium AssemblyTAS
R-HSA-5620912Anchoring of the basal body to the plasma membraneTAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal