Gene: RBM18

92400
-
RNA binding motif protein 18
protein-coding
9q33.2
Ensembl:ENSG00000119446 Vega:OTTHUMG00000020602 UniprotKB:Q96H35
NC_000009.12
SNP Mapped
2   ANCO-SNPs
AD
0   
NA (AD)  NA (ND)   (Frontal_Cortex)
6.946e-1 (AD)  1.247e-1 (ND)

ANCO-SNPs

SNP ID Position Alleles Trait Variation Type
rs7042018chr9:122241249 (GRCh38.p7)A>Galcohol dependenceSNV(Single Nucleotide Variation)
rs10733657chr9:122239706 (GRCh38.p7)C>Talcohol dependenceSNV(Single Nucleotide Variation)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
RNF60.958
AFTPH0.957
RANBP60.957
SHOC20.957
CAND10.956
PPP2R5E0.956
CUL30.955
NUS10.955
ATG50.955
MOB40.954

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
OR4F5-0.587
OR4F29-0.537
CSAG1-0.403
ANPEP-0.35
MAGEA12-0.346
VNN3-0.344
FZD10-0.335
MYL3-0.328
MYOM1-0.328
MTRNR2L10-0.321

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C0095054,4'-diaminodiphenylmethane"4,4'-diaminodiphenylmethane results in increased expression of RBM18 mRNA"18648102
C517041(4-amino-1,4-dihydro-3-(2-pyridyl)-5-thioxo-1,2,4-triazole)copper(II)"(4-amino-1,4-dihydro-3-(2-pyridyl)-5-thioxo-1,2,4-triazole)copper(II) results in increased expression of RBM18 mRNA"19561079
D000082AcetaminophenAcetaminophen affects the expression of RBM18 mRNA17562736
D020106AcrylamideAcrylamide results in increased expression of RBM18 mRNA28959563
D016604Aflatoxin B1Aflatoxin B1 results in increased methylation of RBM18 gene27153756
D016604Aflatoxin B1Aflatoxin B1 results in increased expression of RBM18 mRNA19770486
D001280AtrazineAtrazine results in increased expression of RBM18 mRNA22378314
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of RBM18 mRNA22228805
C044887beta-methylcholinebeta-methylcholine affects the expression of RBM18 mRNA21179406
C006780bisphenol Abisphenol A results in increased expression of RBM18 mRNA25181051
D003300Copper[Disulfiram binds to Copper] which results in decreased expression of RBM18 mRNA24690739
D019327Copper SulfateCopper Sulfate results in increased expression of RBM18 mRNA19549813
D016572CyclosporineCyclosporine results in increased expression of RBM18 mRNA25562108
C089595cylindrospermopsincylindrospermopsin results in increased expression of RBM18 mRNA24921660
D003703DemecolcineDemecolcine results in increased expression of RBM18 mRNA23649840
D003993Dibutyl PhthalateDibutyl Phthalate results in increased expression of RBM18 mRNA21266533
D003993Dibutyl PhthalateDibutyl Phthalate results in increased expression of RBM18 mRNA21266533
D002945CisplatinCisplatin results in increased expression of RBM18 mRNA19561079
C000944dicrotophosdicrotophos results in decreased expression of RBM18 mRNA28302478
D004221Disulfiram[Disulfiram binds to Copper] which results in decreased expression of RBM18 mRNA24690739
D005020Ethyl MethanesulfonateEthyl Methanesulfonate results in increased expression of RBM18 mRNA23649840
D005557FormaldehydeFormaldehyde results in increased expression of RBM18 mRNA23649840
D006861Hydrogen PeroxideHydrogen Peroxide affects the expression of RBM18 mRNA20044591
D006997Hypochlorous AcidHypochlorous Acid results in increased expression of RBM18 mRNA19376150
C492448ICG 001ICG 001 results in increased expression of RBM18 mRNA26191083
C544151jinfukangjinfukang results in decreased expression of RBM18 mRNA27392435
C004925methylmercuric chloridemethylmercuric chloride results in decreased expression of RBM18 mRNA28001369
D008741Methyl MethanesulfonateMethyl Methanesulfonate results in increased expression of RBM18 mRNA23649840
D010426Pentosan Sulfuric PolyesterPentosan Sulfuric Polyester results in increased expression of RBM18 mRNA28973697
D010634PhenobarbitalPhenobarbital affects the expression of RBM18 mRNA19159669
D000952Antigens, Polyomavirus Transforming"Antigens, Polyomavirus Transforming results in increased expression of RBM18 mRNA"26680231
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of RBM18 mRNA21570461
C012589trichostatin Atrichostatin A results in decreased expression of RBM18 mRNA26272509
D014635Valproic AcidValproic Acid results in decreased expression of RBM18 mRNA28001369
D014635Valproic AcidValproic Acid results in decreased methylation of RBM18 gene29154799
D014635Valproic AcidValproic Acid results in increased expression of RBM18 mRNA29154799
D001335Vehicle EmissionsVehicle Emissions results in decreased methylation of RBM18 gene25560391
D014750VincristineVincristine results in increased expression of RBM18 mRNA23649840

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0003723RNA binding-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO ID GO Term Qualifier Evidence PubMed
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal