DegronMD

Uniprot ID: Q8IZF6

Source protein: Adhesion G-protein coupled receptor G4

Source gene: ADGRG4

Class: DEG_SPOP_SBC_1

Location: 543:547

E3 ligase: SPOP

DEGRON score: 0.9609

ASA_SCORE: 74.2

COIL: 0.7806

CONS_SCORE: 0.7552

DSS_SCORE: 0.499

HELIX: 0.0978

FCONS_SCORE: 0.9967

RIG_SCORE: 0.7088

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.E548K	SNU-C5	large_intestine	COSMIC	AMSTS	DEG_SPOP_SBC_1	0.3056

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q8IZF6	Adhesion G-protein coupled receptor G4	DEG_SPOP_SBC_1	543:547	AMSTS	SPOP	0.9609	More...
Q8NET4	Retrotransposon Gag-like protein 9	DEG_SPOP_SBC_1	678:682	AMSTS	SPOP	0.9169	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons