DegronMD

Uniprot ID: Q6AWC2

Source protein: Protein WWC2

Source gene: WWC2

Class: DEG_SCF_TRCP1_1

Location: 609:614

E3 ligase: BTRC

DEGRON score: 0.9733

ASA_SCORE: 65.2

COIL: 0.846

CONS_SCORE: 0.3803

DSS_SCORE: 0.4708

HELIX: 0.1178

FCONS_SCORE: 1.2575

RIG_SCORE: 0.5975

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.I599V	SNU-1040	large_intestine	COSMIC	DSGGAS	DEG_SCF_TRCP1_1	0.0556

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q15772	Striated muscle preferentially expressed protein kinase	DEG_SCF_TRCP1_1	2476:2481	DSGGAS	BTRC	0.9406	More...
Q6AWC2	Protein WWC2	DEG_SCF_TRCP1_1	609:614	DSGGAS	BTRC	0.9733	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons