DegronMD

Uniprot ID: Q6ZTA4

Source protein: Tripartite motif-containing protein 67

Source gene: TRIM67

Class: DEG_SCF_TRCP1_1

Location: 109:114

E3 ligase: BTRC

DEGRON score: 0.9957

ASA_SCORE: 64.0167

COIL: 0.7133

CONS_SCORE: 0.4215

DSS_SCORE: 0.4441

HELIX: 0.0567

FCONS_SCORE: 1.0588

RIG_SCORE: 0.6443

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.G111D	DO222494	MELA	ICGC	DSGYGS	DEG_SCF_TRCP1_1	0.7198
p.S110C	DO229151	THCA	ICGC	DSGYGS	DEG_SCF_TRCP1_1	0.7541
p.A99T	SIDM00949	T-Cell Non-Hodgkin's Lymphoma	GDSC	DSGYGS	DEG_SCF_TRCP1_1	0.0556
p.P120L	HCC1954	breast	COSMIC	DSGYGS	DEG_SCF_TRCP1_1	0.2778

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q9C026	E3 ubiquitin-protein ligase TRIM9	DEG_SCF_TRCP1_1	75:80	DSGYGS	BTRC	0.7947	More...
Q6ZTA4	Tripartite motif-containing protein 67	DEG_SCF_TRCP1_1	109:114	DSGYGS	BTRC	0.9957	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons