DegronMD

Uniprot ID: P21127

Source protein: Cyclin-dependent kinase 11B

Source gene: CDK11B

Class: DEG_APCC_DBOX_1

Location: 272:280

E3 ligase: APC,CDC20,FZR1

DEGRON score: 0.9664

ASA_SCORE: 108.5222

COIL: 0.4972

CONS_SCORE: 0.3154

DSS_SCORE: 0.6912

HELIX: 0.4953

FCONS_SCORE: 1.1902

RIG_SCORE: 0.7387

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.Q268R	DO229264	THCA	ICGC	ERDLLSDLQ	DEG_APCC_DBOX_1	0.2222

DegronMD: protein-targeted degradation, mutation and drug response to degrons