DegronMD

Uniprot ID: Q9UQ88

Source protein: Cyclin-dependent kinase 11A

Source gene: CDK11A

Class: DEG_APCC_DBOX_1

Location: 260:268

E3 ligase: APC,CDC20,FZR1

DEGRON score: 0.9522

ASA_SCORE: 110.2556

COIL: 0.5699

CONS_SCORE: 0.2668

DSS_SCORE: 0.6912

HELIX: 0.4112

FCONS_SCORE: 0.9902

RIG_SCORE: 0.7387

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.Q268R	DO229264	THCA	ICGC	ERDLLSDLQ	DEG_APCC_DBOX_1	0.6218

DegronMD: protein-targeted degradation, mutation and drug response to degrons