DegronMD

Uniprot ID: Q9HBZ2

Source protein: Aryl hydrocarbon receptor nuclear translocator 2

Source gene: ARNT2

Class: LIG_APCC_ABBA_1

Location: 712:717

E3 ligase: APC,CDC20,FZR1

DEGRON score: 0.9804

ASA_SCORE: 95.4

COIL: 0.9485

CONS_SCORE: 0.389

DSS_SCORE: 0.839

HELIX: 0.0357

FCONS_SCORE: 1.1737

RIG_SCORE: 0.7509

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.R704W	GOTO	autonomic_ganglia	COSMIC	FPPFSE	LIG_APCC_ABBA_1	0.1111

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
P27540	Aryl hydrocarbon receptor nuclear translocator	LIG_APCC_ABBA_1	784:789	FPPFSE	APC,CDC20,FZR1	0.8894	More...
Q9HBZ2	Aryl hydrocarbon receptor nuclear translocator 2	LIG_APCC_ABBA_1	712:717	FPPFSE	APC,CDC20,FZR1	0.9804	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons