DegronMD

Uniprot ID: Q5JV73

Source protein: FERM and PDZ domain-containing protein 3

Source gene: FRMPD3

Class: DEG_SCF_FBW7_1

Location: 795:800

E3 ligase: FBXW7

DEGRON score: 0.9064

ASA_SCORE: 88.2667

COIL: 0.9245

CONS_SCORE: 0.3758

DSS_SCORE: 0.5604

HELIX: 0.0247

FCONS_SCORE: 1.0736

RIG_SCORE: 0.686

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.I790S	TCGA-ND-A4WC	UCS	TCGA	ITPESS	DEG_SCF_FBW7_1	0.1944

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q8TBP0	TBC1 domain family member 16	DEG_SCF_FBW7_1	98:103	ITPESS	FBXW7	0.999	More...
Q5JV73	FERM and PDZ domain-containing protein 3	DEG_SCF_FBW7_1	795:800	ITPESS	FBXW7	0.9064	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons