DegronMD: protein-targeted degradation, mutation and drug response to degrons
Home
(current)
Browse
Proteins/Degrons
Mutations
Drug response
Network-rewiring
Drug resistance
Search
Tutorial
Download
Contact
Links
BSML
CPH
CGC
Degron:
LASTPSAT
Uniprot ID:
P0C874
Source protein:
Spermatogenesis-associated protein 31D3
Source gene:
SPATA31D3
Class:
DEG_SCF_FBW7_1
Location:
169:176
E3 ligase:
FBXW7
DEGRON score:
0.8379
ASA_SCORE:
71.4875
COIL:
0.9
CONS_SCORE:
0.3442
DSS_SCORE:
0.546
HELIX:
0.0634
FCONS_SCORE:
1.0177
RIG_SCORE:
0.6114
Degron related mutations and impact score
Mutation
Sample
Cancer
Dataset
Degron
Degron class
Impact score
Drug responses associated with SPATA31D3 mutations
Sample
Cancer
Mutation (In Degron?)
Dataset
Drug
IC50
All proteins holding degron of LASTPSAT
Uniprot ID
Source protein
Degron class
Location
Hit
E3 ligase
Degron score
Detail
P0C874
Spermatogenesis-associated protein 31D3
DEG_SCF_FBW7_1
169:176
LASTPSAT
FBXW7
0.8379
More...
Q6ZQQ2
Spermatogenesis-associated protein 31D1
DEG_SCF_FBW7_1
172:179
LASTPSAT
FBXW7
0.992
More...
Q6ZUB0
Spermatogenesis-associated protein 31D4
DEG_SCF_FBW7_1
169:176
LASTPSAT
FBXW7
0.8197
More...