DegronMD

Uniprot ID: Q9Y4E1

Source protein: WASH complex subunit 2C

Source gene: WASHC2C

Class: LIG_APCC_ABBA_1

Location: 801:806

E3 ligase: APC,CDC20,FZR1

DEGRON score: 0.9951

ASA_SCORE: 79.75

COIL: 0.5865

CONS_SCORE: 0.4922

DSS_SCORE: 0.5649

HELIX: 0.281

FCONS_SCORE: 1.4076

RIG_SCORE: 0.804

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.S815Y	SNU-407	large_intestine	COSMIC	LSLFDE	LIG_APCC_ABBA_1	0.0833

DegronMD: protein-targeted degradation, mutation and drug response to degrons