DegronMD - Q641Q2(WASHC2A)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.G449D	SIDM00661	B-Cell Non-Hodgkin's Lymphoma	GDSC	PTPRKS	DEG_SCF_FBW7_1	436:441	Mutation rewiring degron network	0.1111
p.P442S	SIDM00461	Acute Myeloid Leukemia	GDSC	PTPRKS	DEG_SCF_FBW7_1	436:441	Mutation rewiring degron network	0.3056
p.E949K	SIDM00606	Squamous Cell Lung Carcinoma	GDSC	PETPQDS	DEG_SCF_FBW7_1	933:939	Mutation rewiring degron network	0.0556
p.T1138M	SIDM00429	B-Lymphoblastic Leukemia	GDSC	DSGDIFS	DEG_SCF_TRCP1_1	1131:1137	Mutation rewiring degron network	0.3056
p.A656V	SIDM01029	Esophageal Squamous Cell Carcinoma	GDSC	KTSLFEE	LIG_APCC_ABBAyCdc20_2	661:667	Mutation rewiring degron network	0.1944
p.D1131N	SIDM00628	Breast Carcinoma	GDSC	DSGDIFS	DEG_SCF_TRCP1_1	1131:1137	Mutation altering degron motif	0.6932
p.N581T	SIDM01611	Endometrial Carcinoma	GDSC	VSLFDD	LIG_APCC_ABBA_1	570:575	Mutation rewiring degron network	0.1667
p.D672A	SIDM01588	Endometrial Carcinoma	GDSC	KTSLFEE	LIG_APCC_ABBAyCdc20_2	661:667	Mutation rewiring degron network	0.1944

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons