DegronMD

Uniprot ID: Q711Q0

Source protein: Cardiac-enriched FHL2-interacting protein

Source gene: CEFIP

Class: DEG_SCF_FBW7_1

Location: 841:846

E3 ligase: FBXW7

DEGRON score: 0.9985

ASA_SCORE: 85.4833

COIL: 0.9567

CONS_SCORE: 0.5605

DSS_SCORE: 0.5715

HELIX: 0.0237

FCONS_SCORE: 0.9641

RIG_SCORE: 0.6451

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.A838S	DO229038	LICA	ICGC	LTPSPS	DEG_SCF_FBW7_1	0.25
p.A838P	SIDM00753	Squamous Cell Lung Carcinoma	GDSC	LTPSPS	DEG_SCF_FBW7_1	0.25

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q8TE56	A disintegrin and metalloproteinase with thrombospondin motifs 17	DEG_SCF_FBW7_1	186:191	LTPSPS	FBXW7	0.9711	More...
Q711Q0	Cardiac-enriched FHL2-interacting protein	DEG_SCF_FBW7_1	841:846	LTPSPS	FBXW7	0.9985	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons