DegronMD

Uniprot ID: Q9ULI3

Source protein: Protein HEG homolog 1

Source gene: HEG1

Class: DEG_SCF_FBW7_1

Location: 75:81

E3 ligase: FBXW7

DEGRON score: 0.9608

ASA_SCORE: 86.0571

COIL: 0.9646

CONS_SCORE: 0.2776

DSS_SCORE: 0.8692

HELIX: 0.0187

FCONS_SCORE: 0.9477

RIG_SCORE: 0.4809

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.A90P	ACH-000997	Colon/Colorectal Cancer	CCLE	PATPGPS	DEG_SCF_FBW7_1	0.0833

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q9BXL8	Cell division cycle-associated protein 4	DEG_SCF_FBW7_1	215:221	PATPGPS	FBXW7	0.986	More...
Q9ULI3	Protein HEG homolog 1	DEG_SCF_FBW7_1	75:81	PATPGPS	FBXW7	0.9608	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons