DegronMD

Uniprot ID: Q9NY43

Source protein: BarH-like 2 homeobox protein

Source gene: BARHL2

Class: DEG_SPOP_SBC_1

Location: 159:163

E3 ligase: SPOP

DEGRON score: 0.9217

ASA_SCORE: 80.06

COIL: 0.9076

CONS_SCORE: 0.3537

DSS_SCORE: 0.5258

HELIX: 0.0566

FCONS_SCORE: 0.9531

RIG_SCORE: 0.6375

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.L154V	TCGA-77-7337	LUSC	TCGA	PYSTS	DEG_SPOP_SBC_1	0.1944
p.L154V	DO27445	LUSC	ICGC	PYSTS	DEG_SPOP_SBC_1	0.1944
p.A158T	TCGA-FI-A2D5	UCEC	TCGA	PYSTS	DEG_SPOP_SBC_1	0.3056
p.A158T	DO41331	UCEC	ICGC	PYSTS	DEG_SPOP_SBC_1	0.3056
p.T162I	TCGA-FU-A23K	CESC	TCGA	PYSTS	DEG_SPOP_SBC_1	0.7078
p.T162I	DO6305	CESC	ICGC	PYSTS	DEG_SPOP_SBC_1	0.7078
p.A155V	DO233242	GACA	ICGC	PYSTS	DEG_SPOP_SBC_1	0.2222

DegronMD: protein-targeted degradation, mutation and drug response to degrons