DegronMD

Uniprot ID: Q9BSK2

Source protein: Solute carrier family 25 member 33

Source gene: SLC25A33

Class: DEG_APCC_KENBOX_2

Location: 7:11

E3 ligase: APC,CDC20,FZR1

DEGRON score: 0.5427

ASA_SCORE: 98.28

COIL: 0.7224

CONS_SCORE: 0.3105

DSS_SCORE: 0.3298

HELIX: 0.259

FCONS_SCORE: 0.6558

RIG_SCORE: 0.7776

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.G19W	DO228974	LICA	ICGC	QKENT	DEG_APCC_KENBOX_2	0.1111
p.G19W	DO229026	LICA	ICGC	QKENT	DEG_APCC_KENBOX_2	0.1111
p.L15F	DO37719	SKCM	ICGC	QKENT	DEG_APCC_KENBOX_2	0.2222
p.L12Q	ACH-000982	Colon/Colorectal Cancer	CCLE	QKENT	DEG_APCC_KENBOX_2	0.3056
p.L12Q	ACH-001345	Colon/Colorectal Cancer	CCLE	QKENT	DEG_APCC_KENBOX_2	0.3056

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
P10242	Transcriptional activator Myb	DEG_APCC_KENBOX_2	444:448	QKENT	APC,CDC20,FZR1	0.9949	More...
Q9BSK2	Solute carrier family 25 member 33	DEG_APCC_KENBOX_2	7:11	QKENT	APC,CDC20,FZR1	0.5427	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons