DegronMD: protein-targeted degradation, mutation and drug response to degrons
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Degron:
SMSTGE
Uniprot ID:
Q5TZJ5
Source protein:
Spermatogenesis-associated protein 31A1
Source gene:
SPATA31A1
Class:
DEG_Kelch_Keap1_1
Location:
646:651
E3 ligase:
KEAP1
DEGRON score:
0.739
ASA_SCORE:
80.15
COIL:
0.841
CONS_SCORE:
0.3321
DSS_SCORE:
0.7091
HELIX:
0.1033
FCONS_SCORE:
0.8822
RIG_SCORE:
0.5662
Degron related mutations and impact score
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Degron
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Drug responses associated with SPATA31A1 mutations
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All proteins holding degron of SMSTGE
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Uniprot ID
Source protein
Degron class
Location
Hit
E3 ligase
Degron score
Detail
Q5TZJ5
Spermatogenesis-associated protein 31A1
DEG_Kelch_Keap1_1
646:651
SMSTGE
KEAP1
0.739
More...
Q5VYP0
Spermatogenesis-associated protein 31A3
DEG_Kelch_Keap1_1
646:651
SMSTGE
KEAP1
0.8689
More...
Q5VU36
Spermatogenesis-associated protein 31A5
DEG_Kelch_Keap1_1
646:651
SMSTGE
KEAP1
0.548
More...
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