DegronMD - P30305(CDC25B)

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.L77Q	TCGA-06-1801	GBM	TCGA	SRSRLTHLS	DEG_APCC_DBOX_1	81:89	Mutation rewiring degron network	0.2222
p.L77Q	DO11986	GBM	ICGC	SRSRLTHLS	DEG_APCC_DBOX_1	81:89	Mutation rewiring degron network	0.2222
p.E464D	TCGA-06-5416	GBM	TCGA	IAPCSLDKRVILIF	DEG_ODPH_VHL_1	472:485	Mutation rewiring degron network	0.1111
p.E464D	DO10880	GBM	ICGC	IAPCSLDKRVILIF	DEG_ODPH_VHL_1	472:485	Mutation rewiring degron network	0.1111
p.S89Y	TCGA-22-4601	LUSC	TCGA	SRSRLTHLS	DEG_APCC_DBOX_1	81:89	Mutation altering degron motif	0.712
p.E193D	TCGA-2W-A8YY	CESC	TCGA	DKEND	DEG_APCC_KENBOX_2	191:195	Mutation altering degron motif	0.6758
p.T86M	TCGA-61-1906	OV	TCGA	SRSRLTHLS	DEG_APCC_DBOX_1	81:89	Mutation altering degron motif	0.7423
p.T86M	DO30070	OV	ICGC	SRSRLTHLS	DEG_APCC_DBOX_1	81:89	Mutation altering degron motif	0.7423
p.D191H	TCGA-98-A53I	LUSC	TCGA	DKEND	DEG_APCC_KENBOX_2	191:195	Mutation altering degron motif	0.6577
p.M545T	TCGA-A8-A081	BRCA	TCGA	DYR	CBL_MET	541:543	Mutation rewiring degron network	0.2778
p.M545T	DO2943	BRCA	ICGC	DYR	CBL_MET	541:543	Mutation rewiring degron network	0.2778
p.R92Q	TCGA-AC-A62V	BRCA	TCGA	SRSRLTHLS	DEG_APCC_DBOX_1	81:89	Mutation rewiring degron network	0.25
p.R493C	TCGA-AX-A06F	UCEC	TCGA	IAPCSLDKRVILIF	DEG_ODPH_VHL_1	472:485	Mutation rewiring degron network	0.1111
p.R493C	SIDM01307	Colorectal Carcinoma	GDSC	IAPCSLDKRVILIF	DEG_ODPH_VHL_1	472:485	Mutation rewiring degron network	0.1111
p.E96K	TCGA-B5-A11E	UCEC	TCGA	SRSRLTHLS	DEG_APCC_DBOX_1	81:89	Mutation rewiring degron network	0.1389
p.E96K	TCGA-EY-A1GI	UCEC	TCGA	SRSRLTHLS	DEG_APCC_DBOX_1	81:89	Mutation rewiring degron network	0.1389
p.F489L	TCGA-B5-A11N	UCEC	TCGA	IAPCSLDKRVILIF	DEG_ODPH_VHL_1	472:485	Mutation rewiring degron network	0.2222
p.F489L	DO41458	UCEC	ICGC	IAPCSLDKRVILIF	DEG_ODPH_VHL_1	472:485	Mutation rewiring degron network	0.2222
p.R82H	TCGA-B5-A3FC	UCEC	TCGA	SRSRLTHLS	DEG_APCC_DBOX_1	81:89	Mutation altering degron motif	0.8244
p.R82H	DO41871	UCEC	ICGC	SRSRLTHLS	DEG_APCC_DBOX_1	81:89	Mutation altering degron motif	0.8244
p.R543Q	TCGA-B5-A3FC	UCEC	TCGA	DYR	CBL_MET	541:543	Mutation altering degron motif	0.7329
p.R543Q	DO41871	UCEC	ICGC	DYR	CBL_MET	541:543	Mutation altering degron motif	0.7329
p.P331A	TCGA-BA-6868	HNSC	TCGA	IRPILKRLE	DEG_APCC_DBOX_1	329:337	Mutation altering degron motif	0.6392
p.R338Q	TCGA-BR-7707	STAD	TCGA	IRPILKRLE	DEG_APCC_DBOX_1	329:337	Mutation rewiring degron network	0.3056
p.R338Q	DO38487	STAD	ICGC	IRPILKRLE	DEG_APCC_DBOX_1	329:337	Mutation rewiring degron network	0.3056
p.P339L	TCGA-D5-6928	COAD	TCGA	IRPILKRLE	DEG_APCC_DBOX_1	329:337	Mutation rewiring degron network	0.2778
p.P339L	DO7776	COAD	ICGC	IRPILKRLE	DEG_APCC_DBOX_1	329:337	Mutation rewiring degron network	0.2778
p.A463V	TCGA-EB-A3XB	SKCM	TCGA	IAPCSLDKRVILIF	DEG_ODPH_VHL_1	472:485	Mutation rewiring degron network	0.0833
p.A463V	DO37856	SKCM	ICGC	IAPCSLDKRVILIF	DEG_ODPH_VHL_1	472:485	Mutation rewiring degron network	0.0833
p.P531H	TCGA-EW-A1P0	BRCA	TCGA	DYR	CBL_MET	541:543	Mutation rewiring degron network	0.0556
p.R84H	TCGA-FI-A2D5	UCEC	TCGA	SRSRLTHLS	DEG_APCC_DBOX_1	81:89	Mutation altering degron motif	0.7133
p.P345L	TCGA-GN-A8LK	SKCM	TCGA	IRPILKRLE	DEG_APCC_DBOX_1	329:337	Mutation rewiring degron network	0.1111
p.E198Q	DO219032	BLCA	ICGC	DKEND	DEG_APCC_KENBOX_2	191:195	Mutation rewiring degron network	0.25
p.E198Q	DO219032	BLCA	ICGC	AASSS	DEG_SPOP_SBC_1	184:188	Mutation rewiring degron network	0.0556
p.P467H	DO3007	BRCA	ICGC	IAPCSLDKRVILIF	DEG_ODPH_VHL_1	472:485	Mutation rewiring degron network	0.1944
p.D204H	DO49976	CESC	ICGC	DKEND	DEG_APCC_KENBOX_2	191:195	Mutation blocking ubiquitination signal	0.5278
p.S96I	DO223732	CESC	ICGC	SRSRLTHLS	DEG_APCC_DBOX_1	81:89	Mutation rewiring degron network	0.1389
p.E548K	DO230334	COCA	ICGC	DYR	CBL_MET	541:543	Mutation rewiring degron network	0.1944
p.E548K	SIDM00194	Colorectal Carcinoma	GDSC	DYR	CBL_MET	541:543	Mutation rewiring degron network	0.1944
p.E548K	SIDM01005	Acute Myeloid Leukemia	GDSC	DYR	CBL_MET	541:543	Mutation rewiring degron network	0.1944
p.E548K	SIDM01196	Hepatocellular Carcinoma	GDSC	DYR	CBL_MET	541:543	Mutation rewiring degron network	0.1944
p.E548K	SIDM00380	Acute Myeloid Leukemia	GDSC	DYR	CBL_MET	541:543	Mutation rewiring degron network	0.1944
p.E548K	SIDM01472	Hepatocellular Carcinoma	GDSC	DYR	CBL_MET	541:543	Mutation rewiring degron network	0.1944
p.T492I	DO222596	COCA	ICGC	IAPCSLDKRVILIF	DEG_ODPH_VHL_1	472:485	Mutation rewiring degron network	0.1389
p.N535K	DO50315	ESAD	ICGC	DYR	CBL_MET	541:543	Mutation rewiring degron network	0.1667
p.T195S	DO234330	ESAD	ICGC	DKEND	DEG_APCC_KENBOX_2	191:195	Mutation altering degron motif	0.7116
p.E464Q	DO48256	ESCA	ICGC	IAPCSLDKRVILIF	DEG_ODPH_VHL_1	472:485	Mutation rewiring degron network	0.1111
p.R543L	DO228581	GACA	ICGC	DYR	CBL_MET	541:543	Mutation altering degron motif	0.8428
p.R543L	DO229022	LICA	ICGC	DYR	CBL_MET	541:543	Mutation altering degron motif	0.8428
p.R543W	DO233867	GACA	ICGC	DYR	CBL_MET	541:543	Mutation altering degron motif	0.8634
p.V98L	DO228390	LICA	ICGC	SRSRLTHLS	DEG_APCC_DBOX_1	81:89	Mutation rewiring degron network	0.0833
p.A335S	DO229029	LICA	ICGC	IRPILKRLE	DEG_APCC_DBOX_1	329:337	Mutation altering degron motif	0.7588
p.A335S	DO229009	LICA	ICGC	IRPILKRLE	DEG_APCC_DBOX_1	329:337	Mutation altering degron motif	0.7588
p.R73L	DO229022	LICA	ICGC	SRSRLTHLS	DEG_APCC_DBOX_1	81:89	Mutation rewiring degron network	0.1111
p.C473F	DO229031	LICA	ICGC	IAPCSLDKRVILIF	DEG_ODPH_VHL_1	472:485	Mutation altering degron motif	0.7108
p.N319D	DO22950	LIHC	ICGC	IRPILKRLE	DEG_APCC_DBOX_1	329:337	Mutation rewiring degron network	0.0556
p.S96C	DO52205	LIHC	ICGC	SRSRLTHLS	DEG_APCC_DBOX_1	81:89	Mutation rewiring degron network	0.1389
p.M324R	DO231189	LUSC	ICGC	IRPILKRLE	DEG_APCC_DBOX_1	329:337	Mutation rewiring degron network	0.1944
p.D342Y	DO26447	LUSC	ICGC	IRPILKRLE	DEG_APCC_DBOX_1	329:337	Mutation rewiring degron network	0.1944
p.R320C	DO222415	MELA	ICGC	IRPILKRLE	DEG_APCC_DBOX_1	329:337	Mutation rewiring degron network	0.0833
p.V181M	DO220252	SARC	ICGC	DKEND	DEG_APCC_KENBOX_2	191:195	Mutation rewiring degron network	0.0556
p.V181M	DO220252	SARC	ICGC	AASSS	DEG_SPOP_SBC_1	184:188	Mutation rewiring degron network	0.25
p.Q346K	DO47578	SKCM	ICGC	IRPILKRLE	DEG_APCC_DBOX_1	329:337	Mutation rewiring degron network	0.0833
p.D462N	SIDM02038	Colorectal Carcinoma	GDSC	IAPCSLDKRVILIF	DEG_ODPH_VHL_1	472:485	Mutation rewiring degron network	0.0556
p.S89T	SIDM00524	Small Cell Lung Carcinoma	GDSC	SRSRLTHLS	DEG_APCC_DBOX_1	81:89	Mutation altering degron motif	0.7116
p.S89T	ACH-000703	Lung Cancer	CCLE	SRSRLTHLS	DEG_APCC_DBOX_1	81:89	Mutation altering degron motif	0.7116
p.S89T	DMS-79	lung	COSMIC	SRSRLTHLS	DEG_APCC_DBOX_1	81:89	Mutation altering degron motif	0.7116
p.D343N	SIDM00135	Breast Carcinoma	GDSC	IRPILKRLE	DEG_APCC_DBOX_1	329:337	Mutation rewiring degron network	0.1667
p.D343N	ACH-000148	Breast Cancer	CCLE	IRPILKRLE	DEG_APCC_DBOX_1	329:337	Mutation rewiring degron network	0.1667
p.D343N	Hs-578-T	breast	COSMIC	IRPILKRLE	DEG_APCC_DBOX_1	329:337	Mutation rewiring degron network	0.1667
p.A473V	SIDM00773	Non-Cancerous	GDSC	IAPCSLDKRVILIF	DEG_ODPH_VHL_1	472:485	Mutation altering degron motif	0.6936
p.A473V	SIDM00774	Breast Carcinoma	GDSC	IAPCSLDKRVILIF	DEG_ODPH_VHL_1	472:485	Mutation altering degron motif	0.6936
p.V481I	SIDM00845	Burkitt's Lymphoma	GDSC	IAPCSLDKRVILIF	DEG_ODPH_VHL_1	472:485	Mutation altering degron motif	0.5965
p.R543P	SIDM00495	B-Cell Non-Hodgkin's Lymphoma	GDSC	DYR	CBL_MET	541:543	Mutation altering degron motif	0.7512
p.R543P	ACH-000697	Lymphoma	CCLE	DYR	CBL_MET	541:543	Mutation altering degron motif	0.7512
p.R543P	A3-KAW	haematopoietic and lymphoid tissue	COSMIC	DYR	CBL_MET	541:543	Mutation altering degron motif	0.7512
p.S178N	SIDM01183	Other Solid Cancers	GDSC	AASSS	DEG_SPOP_SBC_1	184:188	Mutation blocking phosphorylation signal	0.6111
p.S178N	ACH-001417	Lung Cancer	CCLE	AASSS	DEG_SPOP_SBC_1	184:188	Mutation blocking phosphorylation signal	0.6111
p.S178N	UMC-11	lung	COSMIC	AASSS	DEG_SPOP_SBC_1	184:188	Mutation blocking phosphorylation signal	0.6111
p.K479R	SIDM01162	Kidney Carcinoma	GDSC	IAPCSLDKRVILIF	DEG_ODPH_VHL_1	472:485	Mutation altering degron motif	0.6126
p.K479R	ACH-001398	Kidney Cancer	CCLE	IAPCSLDKRVILIF	DEG_ODPH_VHL_1	472:485	Mutation altering degron motif	0.6126
p.K479R	SW156	kidney	COSMIC	IAPCSLDKRVILIF	DEG_ODPH_VHL_1	472:485	Mutation altering degron motif	0.6126
p.R175Q	SIDM00094	Kidney Carcinoma	GDSC	AASSS	DEG_SPOP_SBC_1	184:188	Mutation rewiring degron network	0.0833
p.R175Q	SIDM00327	Hodgkin's Lymphoma	GDSC	AASSS	DEG_SPOP_SBC_1	184:188	Mutation rewiring degron network	0.0833
p.P539L	SIDM01068	Non-Small Cell Lung Carcinoma	GDSC	DYR	CBL_MET	541:543	Mutation rewiring degron network	0.2778
p.P539L	ACH-000562	Lung Cancer	CCLE	DYR	CBL_MET	541:543	Mutation rewiring degron network	0.2778
p.P539L	HCC-78	lung	COSMIC	DYR	CBL_MET	541:543	Mutation rewiring degron network	0.2778
p.P331S	SIDM01146	Gastric Carcinoma	GDSC	IRPILKRLE	DEG_APCC_DBOX_1	329:337	Mutation altering degron motif	0.5641
p.P331S	ACH-000932	Gastric Cancer	CCLE	IRPILKRLE	DEG_APCC_DBOX_1	329:337	Mutation altering degron motif	0.5641
p.P331S	NCI-SNU-1	stomach	COSMIC	IRPILKRLE	DEG_APCC_DBOX_1	329:337	Mutation altering degron motif	0.5641
p.P205L	SIDM00999	Bladder Carcinoma	GDSC	DKEND	DEG_APCC_KENBOX_2	191:195	Mutation rewiring degron network	0.0556
p.P205L	ACH-000973	Bladder Cancer	CCLE	DKEND	DEG_APCC_KENBOX_2	191:195	Mutation rewiring degron network	0.0556
p.P205L	639-V	urinary tract	COSMIC	DKEND	DEG_APCC_KENBOX_2	191:195	Mutation rewiring degron network	0.0556
p.C537Y	SIDM00145	T-Lymphoblastic Leukemia	GDSC	DYR	CBL_MET	541:543	Mutation rewiring degron network	0.2222
p.C537Y	ACH-001127	Leukemia	CCLE	DYR	CBL_MET	541:543	Mutation rewiring degron network	0.2222
p.C537Y	MOLT-4	haematopoietic and lymphoid tissue	COSMIC	DYR	CBL_MET	541:543	Mutation rewiring degron network	0.2222
p.E488K	SIDM00688	B-Cell Non-Hodgkin's Lymphoma	GDSC	IAPCSLDKRVILIF	DEG_ODPH_VHL_1	472:485	Mutation rewiring degron network	0.25
p.E488K	ACH-002253	Lymphoma	CCLE	IAPCSLDKRVILIF	DEG_ODPH_VHL_1	472:485	Mutation rewiring degron network	0.25
p.E488K	JSC-1	haematopoietic and lymphoid tissue	COSMIC	IAPCSLDKRVILIF	DEG_ODPH_VHL_1	472:485	Mutation rewiring degron network	0.25
p.E179K	SIDM00220	Ovarian Carcinoma	GDSC	AASSS	DEG_SPOP_SBC_1	184:188	Mutation rewiring degron network	0.1944
p.E179K	SIDM00224	Mesothelioma	GDSC	AASSS	DEG_SPOP_SBC_1	184:188	Mutation rewiring degron network	0.1944
p.E179K	IST-MES1	pleura	COSMIC	AASSS	DEG_SPOP_SBC_1	184:188	Mutation rewiring degron network	0.1944
p.E179K	OC-314	ovary	COSMIC	AASSS	DEG_SPOP_SBC_1	184:188	Mutation rewiring degron network	0.1944
p.R93Q	SIDM00079	Ovarian Carcinoma	GDSC	SRSRLTHLS	DEG_APCC_DBOX_1	81:89	Mutation rewiring degron network	0.2222
p.R93Q	ACH-000811	Ovarian Cancer	CCLE	SRSRLTHLS	DEG_APCC_DBOX_1	81:89	Mutation rewiring degron network	0.2222
p.R93Q	SK-OV-3	ovary	COSMIC	SRSRLTHLS	DEG_APCC_DBOX_1	81:89	Mutation rewiring degron network	0.2222
p.E193Q	SIDM00381	Cervical Carcinoma	GDSC	DKEND	DEG_APCC_KENBOX_2	191:195	Mutation altering degron motif	0.6744
p.E193Q	ACH-002020	Cervical Cancer	CCLE	DKEND	DEG_APCC_KENBOX_2	191:195	Mutation altering degron motif	0.6744
p.E193Q	SKG-IIIa	cervix	COSMIC	DKEND	DEG_APCC_KENBOX_2	191:195	Mutation altering degron motif	0.6744
p.V328M	SIDM01608	Endometrial Carcinoma	GDSC	IRPILKRLE	DEG_APCC_DBOX_1	329:337	Mutation rewiring degron network	0.3056
p.K71T	SIDM01611	Endometrial Carcinoma	GDSC	SRSRLTHLS	DEG_APCC_DBOX_1	81:89	Mutation blocking ubiquitination signal	0.5
p.K71T	ACH-000996	Endometrial/Uterine Cancer	CCLE	SRSRLTHLS	DEG_APCC_DBOX_1	81:89	Mutation blocking ubiquitination signal	0.5
p.K71E	ACH-001421	Eye Cancer	CCLE	SRSRLTHLS	DEG_APCC_DBOX_1	81:89	Mutation blocking ubiquitination signal	0.5
p.D541N	ACH-001573	Leukemia	CCLE	DYR	CBL_MET	541:543	Mutation altering degron motif	0.6932
p.S95Y	ACH-002396	Bone Cancer	CCLE	SRSRLTHLS	DEG_APCC_DBOX_1	81:89	Mutation rewiring degron network	0.1667
p.S95Y	Sarc9371	bone	COSMIC	SRSRLTHLS	DEG_APCC_DBOX_1	81:89	Mutation rewiring degron network	0.1667
p.P191L	639-V	urinary tract	COSMIC	DKEND	DEG_APCC_KENBOX_2	191:195	Mutation altering degron motif	0.7582
p.R179H	SNU-1040	large intestine	COSMIC	AASSS	DEG_SPOP_SBC_1	184:188	Mutation rewiring degron network	0.1944
p.Q539R	SNU-475	liver	COSMIC	DYR	CBL_MET	541:543	Mutation rewiring degron network	0.2778
p.Q539R	MKN45	stomach	COSMIC	DYR	CBL_MET	541:543	Mutation rewiring degron network	0.2778
p.Q539R	TC-YIK	cervix	COSMIC	DYR	CBL_MET	541:543	Mutation rewiring degron network	0.2778
p.Q539R	OSC-20	upper aerodigestive tract	COSMIC	DYR	CBL_MET	541:543	Mutation rewiring degron network	0.2778
p.Q539R	EN	endometrium	COSMIC	DYR	CBL_MET	541:543	Mutation rewiring degron network	0.2778
p.E202K	BT-474	breast	COSMIC	DKEND	DEG_APCC_KENBOX_2	191:195	Mutation rewiring degron network	0.1389
p.Q489R	OSC-20	upper aerodigestive tract	COSMIC	IAPCSLDKRVILIF	DEG_ODPH_VHL_1	472:485	Mutation rewiring degron network	0.2222
p.Q489R	EN	endometrium	COSMIC	IAPCSLDKRVILIF	DEG_ODPH_VHL_1	472:485	Mutation rewiring degron network	0.2222
p.Q489R	SNU-475	liver	COSMIC	IAPCSLDKRVILIF	DEG_ODPH_VHL_1	472:485	Mutation rewiring degron network	0.2222
p.Q489R	MKN45	stomach	COSMIC	IAPCSLDKRVILIF	DEG_ODPH_VHL_1	472:485	Mutation rewiring degron network	0.2222
p.Q489R	TC-YIK	cervix	COSMIC	IAPCSLDKRVILIF	DEG_ODPH_VHL_1	472:485	Mutation rewiring degron network	0.2222
p.S86L	JHU-011	upper aerodigestive tract	COSMIC	SRSRLTHLS	DEG_APCC_DBOX_1	81:89	Mutation altering degron motif	0.7667
p.R79Q	SK-OV-3	ovary	COSMIC	SRSRLTHLS	DEG_APCC_DBOX_1	81:89	Mutation rewiring degron network	0.2778
p.A188V	LIM1215	large intestine	COSMIC	AASSS	DEG_SPOP_SBC_1	184:188	Mutation altering degron motif	0.6936
p.K465R	SW156	kidney	COSMIC	IAPCSLDKRVILIF	DEG_ODPH_VHL_1	472:485	Mutation blocking phosphorylation signal	0.5833
p.W203S	MOLT-4	haematopoietic and lymphoid tissue	COSMIC	DKEND	DEG_APCC_KENBOX_2	191:195	Mutation rewiring degron network	0.1111
p.C473Y	MOLT-4	haematopoietic and lymphoid tissue	COSMIC	IAPCSLDKRVILIF	DEG_ODPH_VHL_1	472:485	Mutation altering degron motif	0.7087
p.F192L	NUGC-3	stomach	COSMIC	DKEND	DEG_APCC_KENBOX_2	191:195	Mutation altering degron motif	0.6981
p.R328C	PSN1	pancreas	COSMIC	IRPILKRLE	DEG_APCC_DBOX_1	329:337	Mutation rewiring degron network	0.3056
p.W176S	MOLT-4	haematopoietic and lymphoid tissue	COSMIC	AASSS	DEG_SPOP_SBC_1	184:188	Mutation rewiring degron network	0.1111
p.S75T	DMS-79	lung	COSMIC	SRSRLTHLS	DEG_APCC_DBOX_1	81:89	Mutation rewiring degron network	0.1667
p.N468S	RPMI-8866	haematopoietic and lymphoid tissue	COSMIC	IAPCSLDKRVILIF	DEG_ODPH_VHL_1	472:485	Mutation rewiring degron network	0.2222
p.E175K	BT-474	breast	COSMIC	AASSS	DEG_SPOP_SBC_1	184:188	Mutation rewiring degron network	0.0833
p.V329I	LS-411N	large intestine	COSMIC	IRPILKRLE	DEG_APCC_DBOX_1	329:337	Mutation altering degron motif	0.7076
p.E474K	JSC-1	haematopoietic and lymphoid tissue	COSMIC	IAPCSLDKRVILIF	DEG_ODPH_VHL_1	472:485	Mutation altering degron motif	0.7022
p.E179Q	SKG-IIIa	cervix	COSMIC	AASSS	DEG_SPOP_SBC_1	184:188	Mutation rewiring degron network	0.1944
p.R479P	A3-KAW	haematopoietic and lymphoid tissue	COSMIC	IAPCSLDKRVILIF	DEG_ODPH_VHL_1	472:485	Mutation altering degron motif	0.7512
p.V90A	EN	endometrium	COSMIC	SRSRLTHLS	DEG_APCC_DBOX_1	81:89	Mutation rewiring degron network	0.3056
p.D329N	Hs-578-T	breast	COSMIC	IRPILKRLE	DEG_APCC_DBOX_1	329:337	Mutation altering degron motif	0.6932
p.P475L	HCC-78	lung	COSMIC	IAPCSLDKRVILIF	DEG_ODPH_VHL_1	472:485	Mutation altering degron motif	0.7582
p.R482H	SNU-81	large intestine	COSMIC	IAPCSLDKRVILIF	DEG_ODPH_VHL_1	472:485	Mutation altering degron motif	0.8244
p.V341L	MOLT-4	haematopoietic and lymphoid tissue	COSMIC	IRPILKRLE	DEG_APCC_DBOX_1	329:337	Mutation rewiring degron network	0.2222
p.N495S	RPMI-8866	haematopoietic and lymphoid tissue	COSMIC	IAPCSLDKRVILIF	DEG_ODPH_VHL_1	472:485	Mutation rewiring degron network	0.0556
p.S81Y	Sarc9371	bone	COSMIC	SRSRLTHLS	DEG_APCC_DBOX_1	81:89	Mutation altering degron motif	0.6009

DegronMD: protein-targeted degradation, mutation and drug response to degrons

CDC25B

UniProt ID: P30305

Entrez ID: 994

Protein name: M-phase inducer phosphatase 2 (EC 3.1.3.48) (Dual specificity phosphatase Cdc25B)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for CDC25B in