DegronMD - P49418(AMPH)

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.Q317K	TCGA-05-4382	LUAD	TCGA	SFFEDNFVPEI	DEG_COP1_1	322:332	Mutation rewiring degron network	0.1944
p.Q317K	TCGA-05-4382	LUAD	TCGA	PKVTPTKE	DEG_SCF_FBW7_2	307:314	Mutation rewiring degron network	0.25
p.Q317K	DO24900	LUAD	ICGC	SFFEDNFVPEI	DEG_COP1_1	322:332	Mutation rewiring degron network	0.1944
p.Q317K	DO24900	LUAD	ICGC	PKVTPTKE	DEG_SCF_FBW7_2	307:314	Mutation rewiring degron network	0.25
p.S377F	TCGA-18-3409	LUSC	TCGA	PEVTPAGS	DEG_SCF_FBW7_1	361:368	Mutation rewiring degron network	0.0833
p.S377F	DO26444	LUSC	ICGC	PEVTPAGS	DEG_SCF_FBW7_1	361:368	Mutation rewiring degron network	0.0833
p.K308N	TCGA-22-1005	LUSC	TCGA	PKVTPTKE	DEG_SCF_FBW7_2	307:314	Mutation altering degron motif	0.5806
p.K308N	DO26632	LUSC	ICGC	PKVTPTKE	DEG_SCF_FBW7_2	307:314	Mutation altering degron motif	0.5806
p.S377C	TCGA-22-4599	LUSC	TCGA	PEVTPAGS	DEG_SCF_FBW7_1	361:368	Mutation rewiring degron network	0.0833
p.S377C	DO26945	LUSC	ICGC	PEVTPAGS	DEG_SCF_FBW7_1	361:368	Mutation rewiring degron network	0.0833
p.S377C	ACH-001591	Lung Cancer	CCLE	PEVTPAGS	DEG_SCF_FBW7_1	361:368	Mutation rewiring degron network	0.0833
p.S377C	NCI-H1417	lung	COSMIC	PEVTPAGS	DEG_SCF_FBW7_1	361:368	Mutation rewiring degron network	0.0833
p.A443S	TCGA-34-2596	LUSC	TCGA	EPLAAVTPA	DEG_SIAH_1	439:447	Mutation altering degron motif	0.6477
p.A443S	DO26508	LUSC	ICGC	EPLAAVTPA	DEG_SIAH_1	439:447	Mutation altering degron motif	0.6477
p.Q339L	TCGA-44-5644	LUAD	TCGA	TTPSQNEVPEV	DEG_COP1_1	335:345	Mutation altering degron motif	0.6654
p.Q339L	DO25153	LUAD	ICGC	TTPSQNEVPEV	DEG_COP1_1	335:345	Mutation altering degron motif	0.6654
p.V363G	TCGA-77-8009	LUSC	TCGA	PEVTPAGS	DEG_SCF_FBW7_1	361:368	Mutation altering degron motif	0.6421
p.V363G	DO27200	LUSC	ICGC	PEVTPAGS	DEG_SCF_FBW7_1	361:368	Mutation altering degron motif	0.6421
p.D355Y	TCGA-77-8133	LUSC	TCGA	TTPSQNEVPEV	DEG_COP1_1	335:345	Mutation rewiring degron network	0.0556
p.D355Y	TCGA-77-8133	LUSC	TCGA	PEVTPAGS	DEG_SCF_FBW7_1	361:368	Mutation rewiring degron network	0.1667
p.D355Y	DO27039	LUSC	ICGC	TTPSQNEVPEV	DEG_COP1_1	335:345	Mutation rewiring degron network	0.0556
p.D355Y	DO27039	LUSC	ICGC	PEVTPAGS	DEG_SCF_FBW7_1	361:368	Mutation rewiring degron network	0.1667
p.P337H	TCGA-78-7148	LUAD	TCGA	TTPSQNEVPEV	DEG_COP1_1	335:345	Mutation altering degron motif	0.6583
p.P337H	DO26112	LUAD	ICGC	TTPSQNEVPEV	DEG_COP1_1	335:345	Mutation altering degron motif	0.6583
p.G300R	TCGA-90-A4ED	LUSC	TCGA	PKVTPTKE	DEG_SCF_FBW7_2	307:314	Mutation rewiring degron network	0.1389
p.G300R	DO45482	LUSC	ICGC	PKVTPTKE	DEG_SCF_FBW7_2	307:314	Mutation rewiring degron network	0.1389
p.E434A	TCGA-A5-A0G1	UCEC	TCGA	EPLAAVTPA	DEG_SIAH_1	439:447	Mutation rewiring degron network	0.1944
p.E434A	DO42472	UCEC	ICGC	EPLAAVTPA	DEG_SIAH_1	439:447	Mutation rewiring degron network	0.1944
p.K313N	TCGA-A5-A0GP	UCEC	TCGA	PKVTPTKE	DEG_SCF_FBW7_2	307:314	Mutation altering degron motif	0.5806
p.K313N	DO41109	UCEC	ICGC	PKVTPTKE	DEG_SCF_FBW7_2	307:314	Mutation altering degron motif	0.5806
p.L354M	TCGA-A5-A2K5	UCEC	TCGA	TTPSQNEVPEV	DEG_COP1_1	335:345	Mutation rewiring degron network	0.0833
p.L354M	TCGA-A5-A2K5	UCEC	TCGA	PEVTPAGS	DEG_SCF_FBW7_1	361:368	Mutation rewiring degron network	0.1389
p.L354M	DO41379	UCEC	ICGC	TTPSQNEVPEV	DEG_COP1_1	335:345	Mutation rewiring degron network	0.0833
p.L354M	DO41379	UCEC	ICGC	PEVTPAGS	DEG_SCF_FBW7_1	361:368	Mutation rewiring degron network	0.1389
p.P330L	TCGA-A6-5667	COAD	TCGA	SFFEDNFVPEI	DEG_COP1_1	322:332	Mutation altering degron motif	0.7582
p.P330L	DO9868	COAD	ICGC	SFFEDNFVPEI	DEG_COP1_1	322:332	Mutation altering degron motif	0.7582
p.F359L	TCGA-AO-A03M	BRCA	TCGA	PEVTPAGS	DEG_SCF_FBW7_1	361:368	Mutation rewiring degron network	0.2778
p.F359L	DO2216	BRCA	ICGC	PEVTPAGS	DEG_SCF_FBW7_1	361:368	Mutation rewiring degron network	0.2778
p.F359L	DO221545	PACA	ICGC	PEVTPAGS	DEG_SCF_FBW7_1	361:368	Mutation rewiring degron network	0.2778
p.K346N	TCGA-AX-A2HC	UCEC	TCGA	TTPSQNEVPEV	DEG_COP1_1	335:345	Mutation rewiring degron network	0.3056
p.K346N	DO41572	UCEC	ICGC	TTPSQNEVPEV	DEG_COP1_1	335:345	Mutation rewiring degron network	0.3056
p.K347N	TCGA-BR-8059	STAD	TCGA	TTPSQNEVPEV	DEG_COP1_1	335:345	Mutation rewiring degron network	0.2778
p.K347N	DO38443	STAD	ICGC	TTPSQNEVPEV	DEG_COP1_1	335:345	Mutation rewiring degron network	0.2778
p.A447T	TCGA-C5-A1BL	CESC	TCGA	EPLAAVTPA	DEG_SIAH_1	439:447	Mutation altering degron motif	0.6028
p.A447T	DO48986	CESC	ICGC	EPLAAVTPA	DEG_SIAH_1	439:447	Mutation altering degron motif	0.6028
p.D357Y	TCGA-EE-A20C	SKCM	TCGA	PEVTPAGS	DEG_SCF_FBW7_1	361:368	Mutation rewiring degron network	0.2222
p.D357Y	DO47665	SKCM	ICGC	PEVTPAGS	DEG_SCF_FBW7_1	361:368	Mutation rewiring degron network	0.2222
p.P343H	TCGA-EE-A2GN	SKCM	TCGA	TTPSQNEVPEV	DEG_COP1_1	335:345	Mutation altering degron motif	0.7694
p.P343H	DO37896	SKCM	ICGC	TTPSQNEVPEV	DEG_COP1_1	335:345	Mutation altering degron motif	0.7694
p.E331Q	TCGA-EK-A3GK	CESC	TCGA	SFFEDNFVPEI	DEG_COP1_1	322:332	Mutation altering degron motif	0.6744
p.E331Q	DO49964	CESC	ICGC	SFFEDNFVPEI	DEG_COP1_1	322:332	Mutation altering degron motif	0.6744
p.D455N	TCGA-FR-A8YC	SKCM	TCGA	EPLAAVTPA	DEG_SIAH_1	439:447	Mutation rewiring degron network	0.1111
p.D455N	DO50301	SKCM	ICGC	EPLAAVTPA	DEG_SIAH_1	439:447	Mutation rewiring degron network	0.1111
p.E325K	TCGA-G2-A3IB	BLCA	TCGA	SFFEDNFVPEI	DEG_COP1_1	322:332	Mutation altering degron motif	0.7022
p.E325K	DO512	BLCA	ICGC	SFFEDNFVPEI	DEG_COP1_1	322:332	Mutation altering degron motif	0.7022
p.E325K	SIDM00773	Non-Cancerous	GDSC	SFFEDNFVPEI	DEG_COP1_1	322:332	Mutation altering degron motif	0.7022
p.E325K	SIDM00855	Other Sarcomas	GDSC	SFFEDNFVPEI	DEG_COP1_1	322:332	Mutation altering degron motif	0.7022
p.E325K	SIDM00774	Breast Carcinoma	GDSC	SFFEDNFVPEI	DEG_COP1_1	322:332	Mutation altering degron motif	0.7022
p.I320N	TCGA-G3-AAV3	LIHC	TCGA	SFFEDNFVPEI	DEG_COP1_1	322:332	Mutation rewiring degron network	0.2778
p.I320N	TCGA-G3-AAV3	LIHC	TCGA	PKVTPTKE	DEG_SCF_FBW7_2	307:314	Mutation rewiring degron network	0.1667
p.I320N	DO52297	LIHC	ICGC	SFFEDNFVPEI	DEG_COP1_1	322:332	Mutation rewiring degron network	0.2778
p.I320N	DO52297	LIHC	ICGC	PKVTPTKE	DEG_SCF_FBW7_2	307:314	Mutation rewiring degron network	0.1667
p.A430P	TCGA-G3-AAV6	LIHC	TCGA	EPLAAVTPA	DEG_SIAH_1	439:447	Mutation rewiring degron network	0.0833
p.A430P	DO52299	LIHC	ICGC	EPLAAVTPA	DEG_SIAH_1	439:447	Mutation rewiring degron network	0.0833
p.P304S	TCGA-GN-A266	SKCM	TCGA	PKVTPTKE	DEG_SCF_FBW7_2	307:314	Mutation rewiring degron network	0.25
p.P304S	DO37432	SKCM	ICGC	PKVTPTKE	DEG_SCF_FBW7_2	307:314	Mutation rewiring degron network	0.25
p.E344K	TCGA-GV-A3QK	BLCA	TCGA	TTPSQNEVPEV	DEG_COP1_1	335:345	Mutation altering degron motif	0.7022
p.E344K	DO563	BLCA	ICGC	TTPSQNEVPEV	DEG_COP1_1	335:345	Mutation altering degron motif	0.7022
p.E344K	DO50388	ESAD	ICGC	TTPSQNEVPEV	DEG_COP1_1	335:345	Mutation altering degron motif	0.7022
p.P361L	TCGA-IB-7651	PAAD	TCGA	PEVTPAGS	DEG_SCF_FBW7_1	361:368	Mutation altering degron motif	0.6471
p.P361L	DO46657	PAAD	ICGC	PEVTPAGS	DEG_SCF_FBW7_1	361:368	Mutation altering degron motif	0.6471
p.P302S	TCGA-OR-A5JF	ACC	TCGA	PKVTPTKE	DEG_SCF_FBW7_2	307:314	Mutation rewiring degron network	0.1944
p.V329F	TCGA-UB-A7MB	LIHC	TCGA	SFFEDNFVPEI	DEG_COP1_1	322:332	Mutation altering degron motif	0.7068
p.V329F	DO52318	LIHC	ICGC	SFFEDNFVPEI	DEG_COP1_1	322:332	Mutation altering degron motif	0.7068
p.V329F	DO229213	THCA	ICGC	SFFEDNFVPEI	DEG_COP1_1	322:332	Mutation altering degron motif	0.7068
p.H373Q	TCGA-UF-A71B	HNSC	TCGA	PEVTPAGS	DEG_SCF_FBW7_1	361:368	Mutation rewiring degron network	0.1944
p.H373Q	DO52107	HNSC	ICGC	PEVTPAGS	DEG_SCF_FBW7_1	361:368	Mutation rewiring degron network	0.1944
p.T310S	TCGA-VQ-A8PH	STAD	TCGA	PKVTPTKE	DEG_SCF_FBW7_2	307:314	Mutation altering degron motif	0.8227
p.T310S	DO222349	STAD	ICGC	PKVTPTKE	DEG_SCF_FBW7_2	307:314	Mutation altering degron motif	0.8227
p.E314K	TCGA-W3-A828	SKCM	TCGA	PKVTPTKE	DEG_SCF_FBW7_2	307:314	Mutation altering degron motif	0.7022
p.E314K	DO51273	SKCM	ICGC	PKVTPTKE	DEG_SCF_FBW7_2	307:314	Mutation altering degron motif	0.7022
p.P431S	TCGA-ZF-AA51	BLCA	TCGA	EPLAAVTPA	DEG_SIAH_1	439:447	Mutation rewiring degron network	0.1111
p.P431S	DO219093	BLCA	ICGC	EPLAAVTPA	DEG_SIAH_1	439:447	Mutation rewiring degron network	0.1111
p.A429V	DO8842	COAD	ICGC	EPLAAVTPA	DEG_SIAH_1	439:447	Mutation rewiring degron network	0.0556
p.A452V	DO8898	COAD	ICGC	EPLAAVTPA	DEG_SIAH_1	439:447	Mutation rewiring degron network	0.1944
p.A452V	DO41644	UCEC	ICGC	EPLAAVTPA	DEG_SIAH_1	439:447	Mutation rewiring degron network	0.1944
p.A452V	DO41871	UCEC	ICGC	EPLAAVTPA	DEG_SIAH_1	439:447	Mutation rewiring degron network	0.1944
p.K454T	DO229016	COCA	ICGC	EPLAAVTPA	DEG_SIAH_1	439:447	Mutation rewiring degron network	0.1389
p.K454T	DO229003	COCA	ICGC	EPLAAVTPA	DEG_SIAH_1	439:447	Mutation rewiring degron network	0.1389
p.K454T	DO229505	LAML	ICGC	EPLAAVTPA	DEG_SIAH_1	439:447	Mutation rewiring degron network	0.1389
p.K454T	DO230525	LUSC	ICGC	EPLAAVTPA	DEG_SIAH_1	439:447	Mutation rewiring degron network	0.1389
p.K454T	DO230535	LUSC	ICGC	EPLAAVTPA	DEG_SIAH_1	439:447	Mutation rewiring degron network	0.1389
p.K454T	DO230538	LUSC	ICGC	EPLAAVTPA	DEG_SIAH_1	439:447	Mutation rewiring degron network	0.1389
p.E331K	DO233147	GACA	ICGC	SFFEDNFVPEI	DEG_COP1_1	322:332	Mutation altering degron motif	0.7022
p.E349D	DO233758	GACA	ICGC	TTPSQNEVPEV	DEG_COP1_1	335:345	Mutation rewiring degron network	0.2222
p.P431L	DO233888	GACA	ICGC	EPLAAVTPA	DEG_SIAH_1	439:447	Mutation rewiring degron network	0.1111
p.A441V	DO14156	HNSC	ICGC	EPLAAVTPA	DEG_SIAH_1	439:447	Mutation altering degron motif	0.6936
p.P330T	DO231983	LICA	ICGC	SFFEDNFVPEI	DEG_COP1_1	322:332	Mutation altering degron motif	0.7031
p.P365T	DO228976	LICA	ICGC	PEVTPAGS	DEG_SCF_FBW7_1	361:368	Mutation altering degron motif	0.7031
p.P365T	SIDM00210	Ovarian Carcinoma	GDSC	PEVTPAGS	DEG_SCF_FBW7_1	361:368	Mutation altering degron motif	0.7031
p.P365T	ACH-000657	Ovarian Cancer	CCLE	PEVTPAGS	DEG_SCF_FBW7_1	361:368	Mutation altering degron motif	0.7031
p.P365T	A2780	ovary	COSMIC	PEVTPAGS	DEG_SCF_FBW7_1	361:368	Mutation altering degron motif	0.7031
p.T456N	DO229015	LICA	ICGC	EPLAAVTPA	DEG_SIAH_1	439:447	Mutation blocking phosphorylation signal	0.5278
p.T364K	DO229028	LICA	ICGC	PEVTPAGS	DEG_SCF_FBW7_1	361:368	Mutation altering degron motif	0.7306
p.P301T	DO229022	LICA	ICGC	PKVTPTKE	DEG_SCF_FBW7_2	307:314	Mutation rewiring degron network	0.1667
p.D451E	DO229038	LICA	ICGC	EPLAAVTPA	DEG_SIAH_1	439:447	Mutation rewiring degron network	0.2222
p.T335K	DO229045	LICA	ICGC	TTPSQNEVPEV	DEG_COP1_1	335:345	Mutation altering degron motif	0.7306
p.A437T	DO229054	LICA	ICGC	EPLAAVTPA	DEG_SIAH_1	439:447	Mutation rewiring degron network	0.2778
p.V342F	DO45233	LIRI	ICGC	TTPSQNEVPEV	DEG_COP1_1	335:345	Mutation altering degron motif	0.7068
p.E439K	DO220877	MELA	ICGC	EPLAAVTPA	DEG_SIAH_1	439:447	Mutation altering degron motif	0.591
p.D355N	DO220891	MELA	ICGC	TTPSQNEVPEV	DEG_COP1_1	335:345	Mutation rewiring degron network	0.0556
p.D355N	DO220891	MELA	ICGC	PEVTPAGS	DEG_SCF_FBW7_1	361:368	Mutation rewiring degron network	0.1667
p.E362K	DO222420	MELA	ICGC	PEVTPAGS	DEG_SCF_FBW7_1	361:368	Mutation altering degron motif	0.591
p.E362K	SIDM01442	Glioma	GDSC	PEVTPAGS	DEG_SCF_FBW7_1	361:368	Mutation altering degron motif	0.591
p.E362K	ACH-000807	Brain Cancer	CCLE	PEVTPAGS	DEG_SCF_FBW7_1	361:368	Mutation altering degron motif	0.591
p.P358S	DO222868	MELA	ICGC	PEVTPAGS	DEG_SCF_FBW7_1	361:368	Mutation rewiring degron network	0.25
p.P330S	DO222843	MELA	ICGC	SFFEDNFVPEI	DEG_COP1_1	322:332	Mutation altering degron motif	0.6752
p.P330A	DO46538	OV	ICGC	SFFEDNFVPEI	DEG_COP1_1	322:332	Mutation altering degron motif	0.7503
p.E318D	DO33037	PACA	ICGC	SFFEDNFVPEI	DEG_COP1_1	322:332	Mutation rewiring degron network	0.2222
p.E318D	DO33037	PACA	ICGC	PKVTPTKE	DEG_SCF_FBW7_2	307:314	Mutation rewiring degron network	0.2222
p.L441M	DO52124	PAEN	ICGC	EPLAAVTPA	DEG_SIAH_1	439:447	Mutation altering degron motif	0.5999
p.D432N	DO51740	STAD	ICGC	EPLAAVTPA	DEG_SIAH_1	439:447	Mutation rewiring degron network	0.1389
p.A445V	DO47903	STAD	ICGC	EPLAAVTPA	DEG_SIAH_1	439:447	Mutation altering degron motif	0.6936
p.F328L	DO229221	THCA	ICGC	SFFEDNFVPEI	DEG_COP1_1	322:332	Mutation altering degron motif	0.587
p.A455T	DO43306	UCEC	ICGC	EPLAAVTPA	DEG_SIAH_1	439:447	Mutation rewiring degron network	0.1111
p.A431D	DO41379	UCEC	ICGC	EPLAAVTPA	DEG_SIAH_1	439:447	Mutation rewiring degron network	0.1111
p.E344G	SIDM02021	Esophageal Carcinoma	GDSC	TTPSQNEVPEV	DEG_COP1_1	335:345	Mutation altering degron motif	0.7199
p.M376I	SIDM00672	Hepatocellular Carcinoma	GDSC	PEVTPAGS	DEG_SCF_FBW7_1	361:368	Mutation rewiring degron network	0.1111
p.M376I	SIDM00926	Non-Small Cell Lung Carcinoma	GDSC	PEVTPAGS	DEG_SCF_FBW7_1	361:368	Mutation rewiring degron network	0.1111
p.M376I	SIDM00969	Ovarian Carcinoma	GDSC	PEVTPAGS	DEG_SCF_FBW7_1	361:368	Mutation rewiring degron network	0.1111
p.M376I	SIDM00690	Head and Neck Carcinoma	GDSC	PEVTPAGS	DEG_SCF_FBW7_1	361:368	Mutation rewiring degron network	0.1111
p.M376I	SIDM00210	Ovarian Carcinoma	GDSC	PEVTPAGS	DEG_SCF_FBW7_1	361:368	Mutation rewiring degron network	0.1111
p.M376I	SIDM00928	Breast Carcinoma	GDSC	PEVTPAGS	DEG_SCF_FBW7_1	361:368	Mutation rewiring degron network	0.1111
p.M376I	SIDM01039	Other Solid Cancers	GDSC	PEVTPAGS	DEG_SCF_FBW7_1	361:368	Mutation rewiring degron network	0.1111
p.M376I	SIDM00879	Breast Carcinoma	GDSC	PEVTPAGS	DEG_SCF_FBW7_1	361:368	Mutation rewiring degron network	0.1111
p.M376I	SIDM00052	Esophageal Squamous Cell Carcinoma	GDSC	PEVTPAGS	DEG_SCF_FBW7_1	361:368	Mutation rewiring degron network	0.1111
p.M376I	SIDM00849	Kidney Carcinoma	GDSC	PEVTPAGS	DEG_SCF_FBW7_1	361:368	Mutation rewiring degron network	0.1111
p.M376I	SIDM01147	Gastric Carcinoma	GDSC	PEVTPAGS	DEG_SCF_FBW7_1	361:368	Mutation rewiring degron network	0.1111
p.M376I	SIDM01072	Squamous Cell Lung Carcinoma	GDSC	PEVTPAGS	DEG_SCF_FBW7_1	361:368	Mutation rewiring degron network	0.1111
p.M376I	SIDM00956	Esophageal Squamous Cell Carcinoma	GDSC	PEVTPAGS	DEG_SCF_FBW7_1	361:368	Mutation rewiring degron network	0.1111
p.M376I	SIDM01387	Small Cell Lung Carcinoma	GDSC	PEVTPAGS	DEG_SCF_FBW7_1	361:368	Mutation rewiring degron network	0.1111
p.P304Q	SIDM00663	Melanoma	GDSC	PKVTPTKE	DEG_SCF_FBW7_2	307:314	Mutation rewiring degron network	0.25
p.P304Q	ACH-000814	Skin Cancer	CCLE	PKVTPTKE	DEG_SCF_FBW7_2	307:314	Mutation rewiring degron network	0.25
p.P304Q	Hs939-T	skin	COSMIC	PKVTPTKE	DEG_SCF_FBW7_2	307:314	Mutation rewiring degron network	0.25
p.D455G	SIDM00608	Plasma Cell Myeloma	GDSC	EPLAAVTPA	DEG_SIAH_1	439:447	Mutation rewiring degron network	0.1111
p.D455G	SIDM00217	Colorectal Carcinoma	GDSC	EPLAAVTPA	DEG_SIAH_1	439:447	Mutation rewiring degron network	0.1111
p.D455G	ACH-000714	Myeloma	CCLE	EPLAAVTPA	DEG_SIAH_1	439:447	Mutation rewiring degron network	0.1111
p.D455G	ACH-000999	Colon/Colorectal Cancer	CCLE	EPLAAVTPA	DEG_SIAH_1	439:447	Mutation rewiring degron network	0.1111
p.D455G	KMS-11	haematopoietic and lymphoid tissue	COSMIC	EPLAAVTPA	DEG_SIAH_1	439:447	Mutation rewiring degron network	0.1111
p.D455G	SNU-1040	large intestine	COSMIC	EPLAAVTPA	DEG_SIAH_1	439:447	Mutation rewiring degron network	0.1111
p.S333N	SIDM00845	Burkitt's Lymphoma	GDSC	SFFEDNFVPEI	DEG_COP1_1	322:332	Mutation rewiring degron network	0.3056
p.S333N	SIDM00845	Burkitt's Lymphoma	GDSC	TTPSQNEVPEV	DEG_COP1_1	335:345	Mutation rewiring degron network	0.2778
p.T310N	SIDM01176	B-Lymphoblastic Leukemia	GDSC	PKVTPTKE	DEG_SCF_FBW7_2	307:314	Mutation altering degron motif	0.8166
p.T310N	ACH-000059	Leukemia	CCLE	PKVTPTKE	DEG_SCF_FBW7_2	307:314	Mutation altering degron motif	0.8166
p.T310N	SUP-B15	haematopoietic and lymphoid tissue	COSMIC	PKVTPTKE	DEG_SCF_FBW7_2	307:314	Mutation altering degron motif	0.8166
p.P375A	SIDM00810	Non-Small Cell Lung Carcinoma	GDSC	PEVTPAGS	DEG_SCF_FBW7_1	361:368	Mutation rewiring degron network	0.1389
p.P375A	ACH-000757	Lung Cancer	CCLE	PEVTPAGS	DEG_SCF_FBW7_1	361:368	Mutation rewiring degron network	0.1389
p.P375A	A427	lung	COSMIC	PEVTPAGS	DEG_SCF_FBW7_1	361:368	Mutation rewiring degron network	0.1389
p.E434D	SIDM00966	Ovarian Carcinoma	GDSC	EPLAAVTPA	DEG_SIAH_1	439:447	Mutation rewiring degron network	0.1944
p.E434D	ACH-002182	Ovarian Cancer	CCLE	EPLAAVTPA	DEG_SIAH_1	439:447	Mutation rewiring degron network	0.1944
p.E434D	OVCA433	ovary	COSMIC	EPLAAVTPA	DEG_SIAH_1	439:447	Mutation rewiring degron network	0.1944
p.E325D	SIDM00384	B-Cell Non-Hodgkin's Lymphoma	GDSC	SFFEDNFVPEI	DEG_COP1_1	322:332	Mutation altering degron motif	0.5647
p.E325D	ACH-001642	Lymphoma	CCLE	SFFEDNFVPEI	DEG_COP1_1	322:332	Mutation altering degron motif	0.5647
p.E325D	SCC-3	haematopoietic and lymphoid tissue	COSMIC	SFFEDNFVPEI	DEG_COP1_1	322:332	Mutation altering degron motif	0.5647
p.P302T	SIDM00208	Glioblastoma	GDSC	PKVTPTKE	DEG_SCF_FBW7_2	307:314	Mutation rewiring degron network	0.1944
p.P302T	ACH-002229	Brain Cancer	CCLE	PKVTPTKE	DEG_SCF_FBW7_2	307:314	Mutation rewiring degron network	0.1944
p.P302T	D-502MG	central nervous system	COSMIC	PKVTPTKE	DEG_SCF_FBW7_2	307:314	Mutation rewiring degron network	0.1944
p.R298W	ACH-000490	Cervical Cancer	CCLE	PKVTPTKE	DEG_SCF_FBW7_2	307:314	Mutation rewiring degron network	0.0833

DegronMD: protein-targeted degradation, mutation and drug response to degrons

AMPH

UniProt ID: P49418

Entrez ID: 273

Protein name: Amphiphysin

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for AMPH in