p.V388M | TCGA-53-7626 | LUAD | TCGA | RHYLHPE | LIG_APCC_ABBAyCdc20_2 | 397:403 | Mutation rewiring degron network | 0.0833 |
p.V388M | SIDM00889 | Cervical Carcinoma | GDSC | RHYLHPE | LIG_APCC_ABBAyCdc20_2 | 397:403 | Mutation rewiring degron network | 0.0833 |
p.V388M | SIDM00351 | Oral Cavity Carcinoma | GDSC | RHYLHPE | LIG_APCC_ABBAyCdc20_2 | 397:403 | Mutation rewiring degron network | 0.0833 |
p.V388M | ACH-001333 | Cervical Cancer | CCLE | RHYLHPE | LIG_APCC_ABBAyCdc20_2 | 397:403 | Mutation rewiring degron network | 0.0833 |
p.V388M | ACH-002029 | Head and Neck Cancer | CCLE | RHYLHPE | LIG_APCC_ABBAyCdc20_2 | 397:403 | Mutation rewiring degron network | 0.0833 |
p.V388M | SAS | upper aerodigestive tract | COSMIC | RHYLHPE | LIG_APCC_ABBAyCdc20_2 | 397:403 | Mutation rewiring degron network | 0.0833 |
p.V388M | C-33-A | cervix | COSMIC | RHYLHPE | LIG_APCC_ABBAyCdc20_2 | 397:403 | Mutation rewiring degron network | 0.0833 |
p.V1223M | TCGA-55-5899 | LUAD | TCGA | SRASLIEVD | DEG_APCC_DBOX_1 | 1229:1237 | Mutation rewiring degron network | 0.1667 |
p.V1223M | TCGA-D1-A16F | UCEC | TCGA | SRASLIEVD | DEG_APCC_DBOX_1 | 1229:1237 | Mutation rewiring degron network | 0.1667 |
p.V1223M | DO26042 | LUAD | ICGC | SRASLIEVD | DEG_APCC_DBOX_1 | 1229:1237 | Mutation rewiring degron network | 0.1667 |
p.V1223M | DO42408 | UCEC | ICGC | SRASLIEVD | DEG_APCC_DBOX_1 | 1229:1237 | Mutation rewiring degron network | 0.1667 |
p.V1223M | SIDM00789 | Colorectal Carcinoma | GDSC | SRASLIEVD | DEG_APCC_DBOX_1 | 1229:1237 | Mutation rewiring degron network | 0.1667 |
p.V1223M | ACH-000997 | Colon/Colorectal Cancer | CCLE | SRASLIEVD | DEG_APCC_DBOX_1 | 1229:1237 | Mutation rewiring degron network | 0.1667 |
p.V1223M | ACH-001061 | Colon/Colorectal Cancer | CCLE | SRASLIEVD | DEG_APCC_DBOX_1 | 1229:1237 | Mutation rewiring degron network | 0.1667 |
p.V1223M | HCT-15 | large intestine | COSMIC | SRASLIEVD | DEG_APCC_DBOX_1 | 1229:1237 | Mutation rewiring degron network | 0.1667 |
p.R1119G | TCGA-61-2113 | OV | TCGA | PTPSVE | DEG_SCF_FBW7_2 | 1123:1128 | Mutation rewiring degron network | 0.2222 |
p.R1119G | DO29328 | OV | ICGC | PTPSVE | DEG_SCF_FBW7_2 | 1123:1128 | Mutation rewiring degron network | 0.2222 |
p.S1126N | TCGA-66-2770 | LUSC | TCGA | PTPSVE | DEG_SCF_FBW7_2 | 1123:1128 | Mutation altering degron motif | 0.5958 |
p.S1126N | DO27556 | LUSC | ICGC | PTPSVE | DEG_SCF_FBW7_2 | 1123:1128 | Mutation altering degron motif | 0.5958 |
p.R1119Q | TCGA-AG-A002 | READ | TCGA | PTPSVE | DEG_SCF_FBW7_2 | 1123:1128 | Mutation rewiring degron network | 0.2222 |
p.R1119Q | TCGA-AX-A2HC | UCEC | TCGA | PTPSVE | DEG_SCF_FBW7_2 | 1123:1128 | Mutation rewiring degron network | 0.2222 |
p.R1119Q | DO41572 | UCEC | ICGC | PTPSVE | DEG_SCF_FBW7_2 | 1123:1128 | Mutation rewiring degron network | 0.2222 |
p.S1220I | TCGA-AX-A2HD | UCEC | TCGA | SRASLIEVD | DEG_APCC_DBOX_1 | 1229:1237 | Mutation rewiring degron network | 0.0833 |
p.S1220I | TCGA-AX-A2HD | UCEC | TCGA | VGSSS | DEG_SPOP_SBC_1 | 1208:1212 | Mutation rewiring degron network | 0.1111 |
p.S1220I | DO42608 | UCEC | ICGC | SRASLIEVD | DEG_APCC_DBOX_1 | 1229:1237 | Mutation rewiring degron network | 0.0833 |
p.S1220I | DO42608 | UCEC | ICGC | VGSSS | DEG_SPOP_SBC_1 | 1208:1212 | Mutation rewiring degron network | 0.1111 |
p.A1243P | TCGA-BR-4362 | STAD | TCGA | SRASLIEVD | DEG_APCC_DBOX_1 | 1229:1237 | Mutation rewiring degron network | 0.1667 |
p.A1243P | DO38336 | STAD | ICGC | SRASLIEVD | DEG_APCC_DBOX_1 | 1229:1237 | Mutation rewiring degron network | 0.1667 |
p.D1240A | TCGA-D7-A4YT | STAD | TCGA | SRASLIEVD | DEG_APCC_DBOX_1 | 1229:1237 | Mutation rewiring degron network | 0.25 |
p.D1240A | DO47723 | STAD | ICGC | SRASLIEVD | DEG_APCC_DBOX_1 | 1229:1237 | Mutation rewiring degron network | 0.25 |
p.E1377Q | TCGA-DG-A2KK | CESC | TCGA | DSGTKCS | DEG_SCF_TRCP1_1 | 1381:1387 | Mutation rewiring degron network | 0.2222 |
p.E1377Q | DO51595 | CESC | ICGC | DSGTKCS | DEG_SCF_TRCP1_1 | 1381:1387 | Mutation rewiring degron network | 0.2222 |
p.T1129M | TCGA-DU-6392 | LGG | TCGA | PTPSVE | DEG_SCF_FBW7_2 | 1123:1128 | Mutation rewiring degron network | 0.3056 |
p.T1129M | DO22237 | LGG | ICGC | PTPSVE | DEG_SCF_FBW7_2 | 1123:1128 | Mutation rewiring degron network | 0.3056 |
p.T1129M | DO35210 | PACA | ICGC | PTPSVE | DEG_SCF_FBW7_2 | 1123:1128 | Mutation rewiring degron network | 0.3056 |
p.D1245N | TCGA-E6-A1LX | UCEC | TCGA | SRASLIEVD | DEG_APCC_DBOX_1 | 1229:1237 | Mutation rewiring degron network | 0.1111 |
p.D1245N | DO41020 | UCEC | ICGC | SRASLIEVD | DEG_APCC_DBOX_1 | 1229:1237 | Mutation rewiring degron network | 0.1111 |
p.D1245N | SIDM00758 | Non-Small Cell Lung Carcinoma | GDSC | SRASLIEVD | DEG_APCC_DBOX_1 | 1229:1237 | Mutation rewiring degron network | 0.1111 |
p.D1245N | SIDM00757 | Non-Small Cell Lung Carcinoma | GDSC | SRASLIEVD | DEG_APCC_DBOX_1 | 1229:1237 | Mutation rewiring degron network | 0.1111 |
p.D1245N | ACH-000590 | Lung Cancer | CCLE | SRASLIEVD | DEG_APCC_DBOX_1 | 1229:1237 | Mutation rewiring degron network | 0.1111 |
p.D1245N | ACH-001137 | Lung Cancer | CCLE | SRASLIEVD | DEG_APCC_DBOX_1 | 1229:1237 | Mutation rewiring degron network | 0.1111 |
p.D1245N | NCI-H1993 | lung | COSMIC | SRASLIEVD | DEG_APCC_DBOX_1 | 1229:1237 | Mutation rewiring degron network | 0.1111 |
p.P1137S | TCGA-EE-A29E | SKCM | TCGA | PTPSVE | DEG_SCF_FBW7_2 | 1123:1128 | Mutation rewiring degron network | 0.0833 |
p.P1137S | DO37831 | SKCM | ICGC | PTPSVE | DEG_SCF_FBW7_2 | 1123:1128 | Mutation rewiring degron network | 0.0833 |
p.P1131S | TCGA-EM-A3FK | THCA | TCGA | PTPSVE | DEG_SCF_FBW7_2 | 1123:1128 | Mutation rewiring degron network | 0.25 |
p.P1131S | DO48064 | THCA | ICGC | PTPSVE | DEG_SCF_FBW7_2 | 1123:1128 | Mutation rewiring degron network | 0.25 |
p.E1246K | TCGA-EO-A3AZ | UCEC | TCGA | SRASLIEVD | DEG_APCC_DBOX_1 | 1229:1237 | Mutation rewiring degron network | 0.0833 |
p.E1246K | DO50078 | UCEC | ICGC | SRASLIEVD | DEG_APCC_DBOX_1 | 1229:1237 | Mutation rewiring degron network | 0.0833 |
p.Q1115H | TCGA-FI-A2D5 | UCEC | TCGA | PTPSVE | DEG_SCF_FBW7_2 | 1123:1128 | Mutation rewiring degron network | 0.1111 |
p.Q1115H | DO41331 | UCEC | ICGC | PTPSVE | DEG_SCF_FBW7_2 | 1123:1128 | Mutation rewiring degron network | 0.1111 |
p.P1137L | TCGA-QH-A6CW | LGG | TCGA | PTPSVE | DEG_SCF_FBW7_2 | 1123:1128 | Mutation rewiring degron network | 0.0833 |
p.P1137L | DO50170 | LGG | ICGC | PTPSVE | DEG_SCF_FBW7_2 | 1123:1128 | Mutation rewiring degron network | 0.0833 |
p.P1244A | TCGA-ZF-A9RE | BLCA | TCGA | SRASLIEVD | DEG_APCC_DBOX_1 | 1229:1237 | Mutation rewiring degron network | 0.1389 |
p.P1244A | DO219072 | BLCA | ICGC | SRASLIEVD | DEG_APCC_DBOX_1 | 1229:1237 | Mutation rewiring degron network | 0.1389 |
p.S1216L | DO229013 | COCA | ICGC | VGSSS | DEG_SPOP_SBC_1 | 1208:1212 | Mutation rewiring degron network | 0.2222 |
p.T1124M | DO234444 | ESAD | ICGC | PTPSVE | DEG_SCF_FBW7_2 | 1123:1128 | Mutation altering degron motif | 0.8534 |
p.P1222S | DO233944 | GACA | ICGC | SRASLIEVD | DEG_APCC_DBOX_1 | 1229:1237 | Mutation rewiring degron network | 0.1389 |
p.P1222S | DO233944 | GACA | ICGC | VGSSS | DEG_SPOP_SBC_1 | 1208:1212 | Mutation rewiring degron network | 0.0556 |
p.P1222S | DO220855 | MELA | ICGC | SRASLIEVD | DEG_APCC_DBOX_1 | 1229:1237 | Mutation rewiring degron network | 0.1389 |
p.P1222S | DO220855 | MELA | ICGC | VGSSS | DEG_SPOP_SBC_1 | 1208:1212 | Mutation rewiring degron network | 0.0556 |
p.P1222T | DO229022 | LICA | ICGC | SRASLIEVD | DEG_APCC_DBOX_1 | 1229:1237 | Mutation rewiring degron network | 0.1389 |
p.P1222T | DO229022 | LICA | ICGC | VGSSS | DEG_SPOP_SBC_1 | 1208:1212 | Mutation rewiring degron network | 0.0556 |
p.T1389N | DO229026 | LICA | ICGC | DSGTKCS | DEG_SCF_TRCP1_1 | 1381:1387 | Mutation blocking phosphorylation signal | 0.7222 |
p.Y410C | DO228901 | LICA | ICGC | RHYLHPE | LIG_APCC_ABBAyCdc20_2 | 397:403 | Mutation substituting flanking lysine | 0.25 |
p.V399M | DO23774 | LUAD | ICGC | RHYLHPE | LIG_APCC_ABBAyCdc20_2 | 397:403 | Mutation altering degron motif | 0.7208 |
p.V399M | C-33-A | cervix | COSMIC | RHYLHPE | LIG_APCC_ABBAyCdc20_2 | 397:403 | Mutation altering degron motif | 0.7208 |
p.V399M | SAS | upper aerodigestive tract | COSMIC | RHYLHPE | LIG_APCC_ABBAyCdc20_2 | 397:403 | Mutation altering degron motif | 0.7208 |
p.E1207K | DO23786 | LUAD | ICGC | VGSSS | DEG_SPOP_SBC_1 | 1208:1212 | Mutation rewiring degron network | 0.3056 |
p.R1113M | DO231141 | LUSC | ICGC | PTPSVE | DEG_SCF_FBW7_2 | 1123:1128 | Mutation rewiring degron network | 0.0556 |
p.P1222L | DO220859 | MELA | ICGC | SRASLIEVD | DEG_APCC_DBOX_1 | 1229:1237 | Mutation rewiring degron network | 0.1389 |
p.P1222L | DO220859 | MELA | ICGC | VGSSS | DEG_SPOP_SBC_1 | 1208:1212 | Mutation rewiring degron network | 0.0556 |
p.VP1221VS | DO220855 | MELA | ICGC | SRASLIEVD | DEG_APCC_DBOX_1 | 1229:1237 | Mutation rewiring degron network | 0 |
p.VP1221VS | DO220855 | MELA | ICGC | VGSSS | DEG_SPOP_SBC_1 | 1208:1212 | Mutation rewiring degron network | 0 |
p.S1212F | DO220877 | MELA | ICGC | VGSSS | DEG_SPOP_SBC_1 | 1208:1212 | Mutation altering degron motif | 0.7982 |
p.T1389I | DO220898 | MELA | ICGC | DSGTKCS | DEG_SCF_TRCP1_1 | 1381:1387 | Mutation blocking phosphorylation signal | 0.7222 |
p.S1117F | DO220906 | MELA | ICGC | PTPSVE | DEG_SCF_FBW7_2 | 1123:1128 | Mutation rewiring degron network | 0.1667 |
p.S1378L | DO222775 | MELA | ICGC | DSGTKCS | DEG_SCF_TRCP1_1 | 1381:1387 | Mutation blocking phosphorylation signal | 0.6944 |
p.S1388Y | DO232052 | ORCA | ICGC | DSGTKCS | DEG_SCF_TRCP1_1 | 1381:1387 | Mutation blocking phosphorylation signal | 0.75 |
p.D1247E | DO47012 | RECA | ICGC | SRASLIEVD | DEG_APCC_DBOX_1 | 1229:1237 | Mutation rewiring degron network | 0.0556 |
p.P1244L | DO219878 | SKCA | ICGC | SRASLIEVD | DEG_APCC_DBOX_1 | 1229:1237 | Mutation rewiring degron network | 0.1389 |
p.G1383A | DO229475 | SKCA | ICGC | DSGTKCS | DEG_SCF_TRCP1_1 | 1381:1387 | Mutation altering degron motif | 0.754 |
p.P1137A | SIDM01123 | Prostate Carcinoma | GDSC | PTPSVE | DEG_SCF_FBW7_2 | 1123:1128 | Mutation rewiring degron network | 0.0833 |
p.P1137A | ACH-000177 | Prostate Cancer | CCLE | PTPSVE | DEG_SCF_FBW7_2 | 1123:1128 | Mutation rewiring degron network | 0.0833 |
p.P1137A | NCI-H660 | prostate | COSMIC | PTPSVE | DEG_SCF_FBW7_2 | 1123:1128 | Mutation rewiring degron network | 0.0833 |
p.S1204N | SIDM00434 | Plasma Cell Myeloma | GDSC | VGSSS | DEG_SPOP_SBC_1 | 1208:1212 | Mutation blocking phosphorylation signal | 0.6667 |
p.S1204N | SIDM00216 | Colorectal Carcinoma | GDSC | VGSSS | DEG_SPOP_SBC_1 | 1208:1212 | Mutation blocking phosphorylation signal | 0.6667 |
p.S1204N | SIDM00958 | Chronic Myelogenous Leukemia | GDSC | VGSSS | DEG_SPOP_SBC_1 | 1208:1212 | Mutation blocking phosphorylation signal | 0.6667 |
p.S1204N | SIDM00267 | Biliary Tract Carcinoma | GDSC | VGSSS | DEG_SPOP_SBC_1 | 1208:1212 | Mutation blocking phosphorylation signal | 0.6667 |
p.S1204N | SIDM00238 | Ovarian Carcinoma | GDSC | VGSSS | DEG_SPOP_SBC_1 | 1208:1212 | Mutation blocking phosphorylation signal | 0.6667 |
p.S1204N | SIDM00619 | Thyroid Gland Carcinoma | GDSC | VGSSS | DEG_SPOP_SBC_1 | 1208:1212 | Mutation blocking phosphorylation signal | 0.6667 |
p.S1204N | SIDM00287 | B-Lymphoblastic Leukemia | GDSC | VGSSS | DEG_SPOP_SBC_1 | 1208:1212 | Mutation blocking phosphorylation signal | 0.6667 |
p.S1204N | SIDM00556 | Neuroblastoma | GDSC | VGSSS | DEG_SPOP_SBC_1 | 1208:1212 | Mutation blocking phosphorylation signal | 0.6667 |
p.S1204N | SIDM00358 | Gastric Carcinoma | GDSC | VGSSS | DEG_SPOP_SBC_1 | 1208:1212 | Mutation blocking phosphorylation signal | 0.6667 |
p.S1204N | SIDM01172 | Acute Myeloid Leukemia | GDSC | VGSSS | DEG_SPOP_SBC_1 | 1208:1212 | Mutation blocking phosphorylation signal | 0.6667 |
p.S1204N | SIDM00487 | Colorectal Carcinoma | GDSC | VGSSS | DEG_SPOP_SBC_1 | 1208:1212 | Mutation blocking phosphorylation signal | 0.6667 |
p.S1204N | SIDM00375 | Head and Neck Carcinoma | GDSC | VGSSS | DEG_SPOP_SBC_1 | 1208:1212 | Mutation blocking phosphorylation signal | 0.6667 |
p.S1204N | SIDM00250 | Esophageal Squamous Cell Carcinoma | GDSC | VGSSS | DEG_SPOP_SBC_1 | 1208:1212 | Mutation blocking phosphorylation signal | 0.6667 |
p.S1204N | SIDM00550 | Esophageal Squamous Cell Carcinoma | GDSC | VGSSS | DEG_SPOP_SBC_1 | 1208:1212 | Mutation blocking phosphorylation signal | 0.6667 |
p.S1204N | SIDM00997 | Thyroid Gland Carcinoma | GDSC | VGSSS | DEG_SPOP_SBC_1 | 1208:1212 | Mutation blocking phosphorylation signal | 0.6667 |
p.S1204N | SIDM00609 | Kidney Carcinoma | GDSC | VGSSS | DEG_SPOP_SBC_1 | 1208:1212 | Mutation blocking phosphorylation signal | 0.6667 |
p.S1204N | SIDM00970 | Bladder Carcinoma | GDSC | VGSSS | DEG_SPOP_SBC_1 | 1208:1212 | Mutation blocking phosphorylation signal | 0.6667 |
p.S1204N | SIDM00566 | Oral Cavity Carcinoma | GDSC | VGSSS | DEG_SPOP_SBC_1 | 1208:1212 | Mutation blocking phosphorylation signal | 0.6667 |
p.S1204N | SIDM00543 | Melanoma | GDSC | VGSSS | DEG_SPOP_SBC_1 | 1208:1212 | Mutation blocking phosphorylation signal | 0.6667 |
p.S1204N | SIDM01511 | Gastric Carcinoma | GDSC | VGSSS | DEG_SPOP_SBC_1 | 1208:1212 | Mutation blocking phosphorylation signal | 0.6667 |
p.S1204N | SIDM01770 | Gastric Carcinoma | GDSC | VGSSS | DEG_SPOP_SBC_1 | 1208:1212 | Mutation blocking phosphorylation signal | 0.6667 |
p.S1204N | SIDM01781 | Gastric Carcinoma | GDSC | VGSSS | DEG_SPOP_SBC_1 | 1208:1212 | Mutation blocking phosphorylation signal | 0.6667 |
p.S1204N | SIDM01573 | Plasma Cell Myeloma | GDSC | VGSSS | DEG_SPOP_SBC_1 | 1208:1212 | Mutation blocking phosphorylation signal | 0.6667 |
p.S1204N | SIDM01685 | B-Lymphoblastic Leukemia | GDSC | VGSSS | DEG_SPOP_SBC_1 | 1208:1212 | Mutation blocking phosphorylation signal | 0.6667 |
p.S1204N | SIDM01391 | Neuroblastoma | GDSC | VGSSS | DEG_SPOP_SBC_1 | 1208:1212 | Mutation blocking phosphorylation signal | 0.6667 |
p.Y399H | SIDM00656 | Burkitt's Lymphoma | GDSC | RHYLHPE | LIG_APCC_ABBAyCdc20_2 | 397:403 | Mutation altering degron motif | 0.6118 |
p.Y399H | SIDM00529 | Breast Carcinoma | GDSC | RHYLHPE | LIG_APCC_ABBAyCdc20_2 | 397:403 | Mutation altering degron motif | 0.6118 |
p.Y399H | SIDM01039 | Other Solid Cancers | GDSC | RHYLHPE | LIG_APCC_ABBAyCdc20_2 | 397:403 | Mutation altering degron motif | 0.6118 |
p.Y399H | SIDM00878 | Breast Carcinoma | GDSC | RHYLHPE | LIG_APCC_ABBAyCdc20_2 | 397:403 | Mutation altering degron motif | 0.6118 |
p.Y399H | SIDM00493 | Other Solid Cancers | GDSC | RHYLHPE | LIG_APCC_ABBAyCdc20_2 | 397:403 | Mutation altering degron motif | 0.6118 |
p.Y399H | SIDM00048 | Non-Small Cell Lung Carcinoma | GDSC | RHYLHPE | LIG_APCC_ABBAyCdc20_2 | 397:403 | Mutation altering degron motif | 0.6118 |
p.Y399H | SIDM00641 | Burkitt's Lymphoma | GDSC | RHYLHPE | LIG_APCC_ABBAyCdc20_2 | 397:403 | Mutation altering degron motif | 0.6118 |
p.S1378W | SIDM01162 | Kidney Carcinoma | GDSC | DSGTKCS | DEG_SCF_TRCP1_1 | 1381:1387 | Mutation blocking phosphorylation signal | 0.6944 |
p.S1378W | ACH-001398 | Kidney Cancer | CCLE | DSGTKCS | DEG_SCF_TRCP1_1 | 1381:1387 | Mutation blocking phosphorylation signal | 0.6944 |
p.L408P | SIDM00333 | Endometrial Carcinoma | GDSC | RHYLHPE | LIG_APCC_ABBAyCdc20_2 | 397:403 | Mutation rewiring degron network | 0.1944 |
p.L408P | MFE-319 | endometrium | COSMIC | RHYLHPE | LIG_APCC_ABBAyCdc20_2 | 397:403 | Mutation rewiring degron network | 0.1944 |
p.S1220C | SIDM00739 | Non-Small Cell Lung Carcinoma | GDSC | SRASLIEVD | DEG_APCC_DBOX_1 | 1229:1237 | Mutation rewiring degron network | 0.0833 |
p.S1220C | SIDM00739 | Non-Small Cell Lung Carcinoma | GDSC | VGSSS | DEG_SPOP_SBC_1 | 1208:1212 | Mutation rewiring degron network | 0.1111 |
p.S1220C | ACH-000675 | Lung Cancer | CCLE | SRASLIEVD | DEG_APCC_DBOX_1 | 1229:1237 | Mutation rewiring degron network | 0.0833 |
p.S1220C | ACH-000675 | Lung Cancer | CCLE | VGSSS | DEG_SPOP_SBC_1 | 1208:1212 | Mutation rewiring degron network | 0.1111 |
p.S1220C | NCI-H1734 | lung | COSMIC | SRASLIEVD | DEG_APCC_DBOX_1 | 1229:1237 | Mutation rewiring degron network | 0.0833 |
p.S1220C | NCI-H1734 | lung | COSMIC | VGSSS | DEG_SPOP_SBC_1 | 1208:1212 | Mutation rewiring degron network | 0.1111 |
p.D1247G | SIDM01135 | Pancreatic Carcinoma | GDSC | SRASLIEVD | DEG_APCC_DBOX_1 | 1229:1237 | Mutation rewiring degron network | 0.0556 |
p.D1247G | ACH-000060 | Pancreatic Cancer | CCLE | SRASLIEVD | DEG_APCC_DBOX_1 | 1229:1237 | Mutation rewiring degron network | 0.0556 |
p.D1247G | PANC-10-05 | pancreas | COSMIC | SRASLIEVD | DEG_APCC_DBOX_1 | 1229:1237 | Mutation rewiring degron network | 0.0556 |
p.C1379Y | SIDM00951 | T-Lymphoblastic Leukemia | GDSC | DSGTKCS | DEG_SCF_TRCP1_1 | 1381:1387 | Mutation rewiring degron network | 0.2778 |
p.C1379Y | ACH-001737 | Leukemia | CCLE | DSGTKCS | DEG_SCF_TRCP1_1 | 1381:1387 | Mutation rewiring degron network | 0.2778 |
p.C1379Y | ACH-002222 | Leukemia | CCLE | DSGTKCS | DEG_SCF_TRCP1_1 | 1381:1387 | Mutation rewiring degron network | 0.2778 |
p.A397T | CCRF-CEM | haematopoietic and lymphoid tissue | COSMIC | RHYLHPE | LIG_APCC_ABBAyCdc20_2 | 397:403 | Mutation altering degron motif | 0.7139 |
p.A388S | LS-411N | large intestine | COSMIC | RHYLHPE | LIG_APCC_ABBAyCdc20_2 | 397:403 | Mutation rewiring degron network | 0.0833 |
p.V1234M | HCT-15 | large intestine | COSMIC | SRASLIEVD | DEG_APCC_DBOX_1 | 1229:1237 | Mutation altering degron motif | 0.7208 |
p.P1372R | RO82-W-1 | thyroid | COSMIC | DSGTKCS | DEG_SCF_TRCP1_1 | 1381:1387 | Mutation blocking phosphorylation signal | 0.5278 |
p.S1231C | NCI-H1734 | lung | COSMIC | SRASLIEVD | DEG_APCC_DBOX_1 | 1229:1237 | Mutation altering degron motif | 0.7541 |
p.R1239C | SNU-1040 | large intestine | COSMIC | SRASLIEVD | DEG_APCC_DBOX_1 | 1229:1237 | Mutation blocking phosphorylation signal | 0.7222 |
p.S1203L | RVH-421 | skin | COSMIC | VGSSS | DEG_SPOP_SBC_1 | 1208:1212 | Mutation rewiring degron network | 0.1944 |