DegronMD - Q96H15(TIMD4)

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.R128C	TCGA-06-0190	GBM	TCGA	ASTTT	DEG_SPOP_SBC_1	134:138	Mutation rewiring degron network	0.1667
p.R128C	TCGA-CG-4300	STAD	TCGA	ASTTT	DEG_SPOP_SBC_1	134:138	Mutation rewiring degron network	0.1667
p.R128C	DO10975	GBM	ICGC	ASTTT	DEG_SPOP_SBC_1	134:138	Mutation rewiring degron network	0.1667
p.R128C	DO38767	STAD	ICGC	ASTTT	DEG_SPOP_SBC_1	134:138	Mutation rewiring degron network	0.1667
p.R128C	SIDM00945	Colorectal Carcinoma	GDSC	ASTTT	DEG_SPOP_SBC_1	134:138	Mutation rewiring degron network	0.1667
p.R128C	SIDM00217	Colorectal Carcinoma	GDSC	ASTTT	DEG_SPOP_SBC_1	134:138	Mutation rewiring degron network	0.1667
p.R128C	ACH-000895	Colon/Colorectal Cancer	CCLE	ASTTT	DEG_SPOP_SBC_1	134:138	Mutation rewiring degron network	0.1667
p.R128C	ACH-000999	Colon/Colorectal Cancer	CCLE	ASTTT	DEG_SPOP_SBC_1	134:138	Mutation rewiring degron network	0.1667
p.R128C	SNU-1040	large intestine	COSMIC	ASTTT	DEG_SPOP_SBC_1	134:138	Mutation rewiring degron network	0.1667
p.R128C	CL-34	large intestine	COSMIC	ASTTT	DEG_SPOP_SBC_1	134:138	Mutation rewiring degron network	0.1667
p.G211V	TCGA-17-Z026	LUAD	TCGA	LLTPEPS	DEG_SCF_FBW7_1	212:218	Mutation rewiring degron network	0.3056
p.V172L	TCGA-17-Z031	LUAD	TCGA	VVTTPDLT	DEG_SCF_FBW7_1	171:178	Mutation altering degron motif	0.5654
p.R140K	TCGA-21-1079	LUSC	TCGA	ASTTT	DEG_SPOP_SBC_1	134:138	Mutation rewiring degron network	0.2778
p.R140K	TCGA-D3-A1Q6	SKCM	TCGA	ASTTT	DEG_SPOP_SBC_1	134:138	Mutation rewiring degron network	0.2778
p.R140K	DO26846	LUSC	ICGC	ASTTT	DEG_SPOP_SBC_1	134:138	Mutation rewiring degron network	0.2778
p.R140K	DO37450	SKCM	ICGC	ASTTT	DEG_SPOP_SBC_1	134:138	Mutation rewiring degron network	0.2778
p.T210I	TCGA-21-5787	LUSC	TCGA	LLTPEPS	DEG_SCF_FBW7_1	212:218	Mutation rewiring degron network	0.2778
p.T210I	DO26605	LUSC	ICGC	LLTPEPS	DEG_SCF_FBW7_1	212:218	Mutation rewiring degron network	0.2778
p.L249R	TCGA-44-2659	LUAD	TCGA	VESTS	DEG_SPOP_SBC_1	240:244	Mutation rewiring degron network	0.1944
p.L249R	DO23744	LUAD	ICGC	VESTS	DEG_SPOP_SBC_1	240:244	Mutation rewiring degron network	0.1944
p.P206Q	TCGA-55-7994	LUAD	TCGA	LLTPEPS	DEG_SCF_FBW7_1	212:218	Mutation rewiring degron network	0.1667
p.P206Q	DO45311	LUAD	ICGC	LLTPEPS	DEG_SCF_FBW7_1	212:218	Mutation rewiring degron network	0.1667
p.S203N	TCGA-56-1622	LUSC	TCGA	LLTPEPS	DEG_SCF_FBW7_1	212:218	Mutation rewiring degron network	0.0833
p.S203N	DO26461	LUSC	ICGC	LLTPEPS	DEG_SCF_FBW7_1	212:218	Mutation rewiring degron network	0.0833
p.Q132L	TCGA-77-8136	LUSC	TCGA	ASTTT	DEG_SPOP_SBC_1	134:138	Mutation rewiring degron network	0.2778
p.Q132L	DO26593	LUSC	ICGC	ASTTT	DEG_SPOP_SBC_1	134:138	Mutation rewiring degron network	0.2778
p.P217H	TCGA-77-A5G6	LUSC	TCGA	LLTPEPS	DEG_SCF_FBW7_1	212:218	Mutation altering degron motif	0.6583
p.P217H	DO50097	LUSC	ICGC	LLTPEPS	DEG_SCF_FBW7_1	212:218	Mutation altering degron motif	0.6583
p.P164L	TCGA-78-7146	LUAD	TCGA	VVTTPDLT	DEG_SCF_FBW7_1	171:178	Mutation rewiring degron network	0.1389
p.P164L	DO23717	LUAD	ICGC	VVTTPDLT	DEG_SCF_FBW7_1	171:178	Mutation rewiring degron network	0.1389
p.T137N	TCGA-86-7955	LUAD	TCGA	ASTTT	DEG_SPOP_SBC_1	134:138	Mutation altering degron motif	0.7055
p.T137N	DO229045	LICA	ICGC	ASTTT	DEG_SPOP_SBC_1	134:138	Mutation altering degron motif	0.7055
p.T137N	DO23612	LUAD	ICGC	ASTTT	DEG_SPOP_SBC_1	134:138	Mutation altering degron motif	0.7055
p.S239I	TCGA-92-8065	LUSC	TCGA	VESTS	DEG_SPOP_SBC_1	240:244	Mutation rewiring degron network	0.3056
p.S239I	DO27074	LUSC	ICGC	VESTS	DEG_SPOP_SBC_1	240:244	Mutation rewiring degron network	0.3056
p.R147H	TCGA-A5-A0GA	UCEC	TCGA	ASTTT	DEG_SPOP_SBC_1	134:138	Mutation rewiring degron network	0.0833
p.R147H	TCGA-D1-A15X	UCEC	TCGA	ASTTT	DEG_SPOP_SBC_1	134:138	Mutation rewiring degron network	0.0833
p.R147H	DO43274	UCEC	ICGC	ASTTT	DEG_SPOP_SBC_1	134:138	Mutation rewiring degron network	0.0833
p.R147H	DO43763	UCEC	ICGC	ASTTT	DEG_SPOP_SBC_1	134:138	Mutation rewiring degron network	0.0833
p.S244Y	TCGA-AJ-A3EK	UCEC	TCGA	VESTS	DEG_SPOP_SBC_1	240:244	Mutation altering degron motif	0.712
p.S244Y	DO41584	UCEC	ICGC	VESTS	DEG_SPOP_SBC_1	240:244	Mutation altering degron motif	0.712
p.D176N	TCGA-AP-A1DV	UCEC	TCGA	VVTTPDLT	DEG_SCF_FBW7_1	171:178	Mutation altering degron motif	0.5821
p.D176N	DO43186	UCEC	ICGC	VVTTPDLT	DEG_SCF_FBW7_1	171:178	Mutation altering degron motif	0.5821
p.T230A	TCGA-AX-A06F	UCEC	TCGA	VESTS	DEG_SPOP_SBC_1	240:244	Mutation rewiring degron network	0.0556
p.T230A	DO41752	UCEC	ICGC	VESTS	DEG_SPOP_SBC_1	240:244	Mutation rewiring degron network	0.0556
p.G180R	TCGA-AX-A3FT	UCEC	TCGA	VVTTPDLT	DEG_SCF_FBW7_1	171:178	Mutation rewiring degron network	0.2778
p.G180R	DO40801	UCEC	ICGC	VVTTPDLT	DEG_SCF_FBW7_1	171:178	Mutation rewiring degron network	0.2778
p.G180R	SIDM00449	B-Lymphoblastic Leukemia	GDSC	VVTTPDLT	DEG_SCF_FBW7_1	171:178	Mutation rewiring degron network	0.2778
p.G180R	SIDM00429	B-Lymphoblastic Leukemia	GDSC	VVTTPDLT	DEG_SCF_FBW7_1	171:178	Mutation rewiring degron network	0.2778
p.S252F	TCGA-B5-A3FC	UCEC	TCGA	VESTS	DEG_SPOP_SBC_1	240:244	Mutation rewiring degron network	0.1111
p.S252F	DO41871	UCEC	ICGC	VESTS	DEG_SPOP_SBC_1	240:244	Mutation rewiring degron network	0.1111
p.R147C	TCGA-BH-A18F	BRCA	TCGA	ASTTT	DEG_SPOP_SBC_1	134:138	Mutation rewiring degron network	0.0833
p.R147C	DO4074	BRCA	ICGC	ASTTT	DEG_SPOP_SBC_1	134:138	Mutation rewiring degron network	0.0833
p.R147C	DO233020	GACA	ICGC	ASTTT	DEG_SPOP_SBC_1	134:138	Mutation rewiring degron network	0.0833
p.R147C	DO227579	ORCA	ICGC	ASTTT	DEG_SPOP_SBC_1	134:138	Mutation rewiring degron network	0.0833
p.R147C	SIDM00150	Colorectal Carcinoma	GDSC	ASTTT	DEG_SPOP_SBC_1	134:138	Mutation rewiring degron network	0.0833
p.L205I	TCGA-CC-A8HT	LIHC	TCGA	LLTPEPS	DEG_SCF_FBW7_1	212:218	Mutation rewiring degron network	0.1389
p.L205I	DO52187	LIHC	ICGC	LLTPEPS	DEG_SCF_FBW7_1	212:218	Mutation rewiring degron network	0.1389
p.R128H	TCGA-CM-4750	COAD	TCGA	ASTTT	DEG_SPOP_SBC_1	134:138	Mutation rewiring degron network	0.1667
p.R128H	TCGA-L5-A8NE	ESCA	TCGA	ASTTT	DEG_SPOP_SBC_1	134:138	Mutation rewiring degron network	0.1667
p.R128H	DO9298	COAD	ICGC	ASTTT	DEG_SPOP_SBC_1	134:138	Mutation rewiring degron network	0.1667
p.R128H	DO232761	PBCA	ICGC	ASTTT	DEG_SPOP_SBC_1	134:138	Mutation rewiring degron network	0.1667
p.R133G	TCGA-CV-A463	HNSC	TCGA	ASTTT	DEG_SPOP_SBC_1	134:138	Mutation rewiring degron network	0.3056
p.R133G	DO52066	HNSC	ICGC	ASTTT	DEG_SPOP_SBC_1	134:138	Mutation rewiring degron network	0.3056
p.L183I	TCGA-D1-A103	UCEC	TCGA	VVTTPDLT	DEG_SCF_FBW7_1	171:178	Mutation rewiring degron network	0.1944
p.L183I	DO42312	UCEC	ICGC	VVTTPDLT	DEG_SCF_FBW7_1	171:178	Mutation rewiring degron network	0.1944
p.E208K	TCGA-D3-A2JP	SKCM	TCGA	LLTPEPS	DEG_SCF_FBW7_1	212:218	Mutation rewiring degron network	0.2222
p.E208K	DO229456	SKCA	ICGC	LLTPEPS	DEG_SCF_FBW7_1	212:218	Mutation rewiring degron network	0.2222
p.E208K	DO47407	SKCM	ICGC	LLTPEPS	DEG_SCF_FBW7_1	212:218	Mutation rewiring degron network	0.2222
p.A245T	TCGA-DM-A1D6	COAD	TCGA	VESTS	DEG_SPOP_SBC_1	240:244	Mutation rewiring degron network	0.3056
p.A245T	DO10686	COAD	ICGC	VESTS	DEG_SPOP_SBC_1	240:244	Mutation rewiring degron network	0.3056
p.A142T	TCGA-DU-7302	LGG	TCGA	ASTTT	DEG_SPOP_SBC_1	134:138	Mutation rewiring degron network	0.2222
p.A142T	DO22728	LGG	ICGC	ASTTT	DEG_SPOP_SBC_1	134:138	Mutation rewiring degron network	0.2222
p.P168S	TCGA-EE-A2GJ	SKCM	TCGA	VVTTPDLT	DEG_SCF_FBW7_1	171:178	Mutation rewiring degron network	0.25
p.P168S	TCGA-ER-A193	SKCM	TCGA	VVTTPDLT	DEG_SCF_FBW7_1	171:178	Mutation rewiring degron network	0.25
p.P168S	DO37746	SKCM	ICGC	VVTTPDLT	DEG_SCF_FBW7_1	171:178	Mutation rewiring degron network	0.25
p.P168S	DO47368	SKCM	ICGC	VVTTPDLT	DEG_SCF_FBW7_1	171:178	Mutation rewiring degron network	0.25
p.L232F	TCGA-EE-A2MS	SKCM	TCGA	VESTS	DEG_SPOP_SBC_1	240:244	Mutation rewiring degron network	0.1111
p.L232F	DO37567	SKCM	ICGC	VESTS	DEG_SPOP_SBC_1	240:244	Mutation rewiring degron network	0.1111
p.P175L	TCGA-FR-A7U9	SKCM	TCGA	VVTTPDLT	DEG_SCF_FBW7_1	171:178	Mutation altering degron motif	0.7582
p.P175L	DO48546	SKCM	ICGC	VVTTPDLT	DEG_SCF_FBW7_1	171:178	Mutation altering degron motif	0.7582
p.P164S	TCGA-FW-A3R5	SKCM	TCGA	VVTTPDLT	DEG_SCF_FBW7_1	171:178	Mutation rewiring degron network	0.1389
p.P164S	DO37406	SKCM	ICGC	VVTTPDLT	DEG_SCF_FBW7_1	171:178	Mutation rewiring degron network	0.1389
p.P202T	TCGA-NC-A5HI	LUSC	TCGA	LLTPEPS	DEG_SCF_FBW7_1	212:218	Mutation rewiring degron network	0.0556
p.P202T	DO45461	LUSC	ICGC	LLTPEPS	DEG_SCF_FBW7_1	212:218	Mutation rewiring degron network	0.0556
p.P202S	TCGA-R8-A6MO	LGG	TCGA	LLTPEPS	DEG_SCF_FBW7_1	212:218	Mutation rewiring degron network	0.0556
p.P202S	DO48508	LGG	ICGC	LLTPEPS	DEG_SCF_FBW7_1	212:218	Mutation rewiring degron network	0.0556
p.S228L	TCGA-T2-A6X0	HNSC	TCGA	LLTPEPS	DEG_SCF_FBW7_1	212:218	Mutation rewiring degron network	0.0556
p.S228L	DO219069	HNSC	ICGC	LLTPEPS	DEG_SCF_FBW7_1	212:218	Mutation rewiring degron network	0.0556
p.D235N	TCGA-W3-A825	SKCM	TCGA	VESTS	DEG_SPOP_SBC_1	240:244	Mutation rewiring degron network	0.1944
p.D235N	DO51272	SKCM	ICGC	VESTS	DEG_SPOP_SBC_1	240:244	Mutation rewiring degron network	0.1944
p.G221E	TCGA-Z2-A8RT	SKCM	TCGA	LLTPEPS	DEG_SCF_FBW7_1	212:218	Mutation rewiring degron network	0.25
p.G221E	DO51301	SKCM	ICGC	LLTPEPS	DEG_SCF_FBW7_1	212:218	Mutation rewiring degron network	0.25
p.V240A	DO229010	COCA	ICGC	VESTS	DEG_SPOP_SBC_1	240:244	Mutation altering degron motif	0.5825
p.V240A	DO229013	COCA	ICGC	VESTS	DEG_SPOP_SBC_1	240:244	Mutation altering degron motif	0.5825
p.V240A	DO229016	COCA	ICGC	VESTS	DEG_SPOP_SBC_1	240:244	Mutation altering degron motif	0.5825
p.V240A	DO229003	COCA	ICGC	VESTS	DEG_SPOP_SBC_1	240:244	Mutation altering degron motif	0.5825
p.V240A	DO229005	COCA	ICGC	VESTS	DEG_SPOP_SBC_1	240:244	Mutation altering degron motif	0.5825
p.E216A	DO217814	GACA	ICGC	LLTPEPS	DEG_SCF_FBW7_1	212:218	Mutation altering degron motif	0.659
p.V127M	DO233776	GACA	ICGC	ASTTT	DEG_SPOP_SBC_1	134:138	Mutation rewiring degron network	0.1389
p.R147S	DO228986	LICA	ICGC	ASTTT	DEG_SPOP_SBC_1	134:138	Mutation rewiring degron network	0.0833
p.R147S	DO50737	LICA	ICGC	ASTTT	DEG_SPOP_SBC_1	134:138	Mutation rewiring degron network	0.0833
p.A134D	DO228986	LICA	ICGC	ASTTT	DEG_SPOP_SBC_1	134:138	Mutation altering degron motif	0.7793
p.T141K	DO229008	LICA	ICGC	ASTTT	DEG_SPOP_SBC_1	134:138	Mutation rewiring degron network	0.25
p.P168Q	DO229008	LICA	ICGC	VVTTPDLT	DEG_SCF_FBW7_1	171:178	Mutation rewiring degron network	0.25
p.V172M	DO231072	LUSC	ICGC	VVTTPDLT	DEG_SCF_FBW7_1	171:178	Mutation altering degron motif	0.6097
p.V172M	SIDM00114	Non-Small Cell Lung Carcinoma	GDSC	VVTTPDLT	DEG_SCF_FBW7_1	171:178	Mutation altering degron motif	0.6097
p.P215S	DO220862	MELA	ICGC	LLTPEPS	DEG_SCF_FBW7_1	212:218	Mutation altering degron motif	0.6752
p.E220K	DO220877	MELA	ICGC	LLTPEPS	DEG_SCF_FBW7_1	212:218	Mutation rewiring degron network	0.2778
p.T145I	DO222595	MELA	ICGC	ASTTT	DEG_SPOP_SBC_1	134:138	Mutation rewiring degron network	0.1389
p.L250P	DO232832	NACA	ICGC	VESTS	DEG_SPOP_SBC_1	240:244	Mutation rewiring degron network	0.1667
p.T173A	DO232761	PBCA	ICGC	VVTTPDLT	DEG_SCF_FBW7_1	171:178	Mutation altering degron motif	0.6028
p.E207K	DO229446	SKCA	ICGC	LLTPEPS	DEG_SCF_FBW7_1	212:218	Mutation rewiring degron network	0.1944
p.Q132K	DO229232	THCA	ICGC	ASTTT	DEG_SPOP_SBC_1	134:138	Mutation rewiring degron network	0.2778
p.T204I	SIDM01104	Melanoma	GDSC	LLTPEPS	DEG_SCF_FBW7_1	212:218	Mutation rewiring degron network	0.1111
p.T204I	ACH-000640	Skin Cancer	CCLE	LLTPEPS	DEG_SCF_FBW7_1	212:218	Mutation rewiring degron network	0.1111
p.T204I	SK-MEL-31	skin	COSMIC	LLTPEPS	DEG_SCF_FBW7_1	212:218	Mutation rewiring degron network	0.1111
p.T162A	SIDM01090	Colorectal Carcinoma	GDSC	VVTTPDLT	DEG_SCF_FBW7_1	171:178	Mutation rewiring degron network	0.0833
p.T162A	ACH-000943	Colon/Colorectal Cancer	CCLE	VVTTPDLT	DEG_SCF_FBW7_1	171:178	Mutation rewiring degron network	0.0833
p.T162A	RKO	large intestine	COSMIC	VVTTPDLT	DEG_SCF_FBW7_1	171:178	Mutation rewiring degron network	0.0833
p.T179I	SIDM00855	Other Sarcomas	GDSC	VVTTPDLT	DEG_SCF_FBW7_1	171:178	Mutation rewiring degron network	0.3056
p.T179I	SIDM00656	Burkitt's Lymphoma	GDSC	VVTTPDLT	DEG_SCF_FBW7_1	171:178	Mutation rewiring degron network	0.3056
p.T179I	SIDM00633	Breast Carcinoma	GDSC	VVTTPDLT	DEG_SCF_FBW7_1	171:178	Mutation rewiring degron network	0.3056
p.T179I	SIDM00048	Non-Small Cell Lung Carcinoma	GDSC	VVTTPDLT	DEG_SCF_FBW7_1	171:178	Mutation rewiring degron network	0.3056
p.T179I	SIDM00254	Neuroblastoma	GDSC	VVTTPDLT	DEG_SCF_FBW7_1	171:178	Mutation rewiring degron network	0.3056
p.T179I	SIDM00844	Burkitt's Lymphoma	GDSC	VVTTPDLT	DEG_SCF_FBW7_1	171:178	Mutation rewiring degron network	0.3056
p.T179I	SIDM01133	Other Solid Cancers	GDSC	VVTTPDLT	DEG_SCF_FBW7_1	171:178	Mutation rewiring degron network	0.3056
p.T179I	SIDM01229	Neuroblastoma	GDSC	VVTTPDLT	DEG_SCF_FBW7_1	171:178	Mutation rewiring degron network	0.3056
p.T179I	SIDM00641	Burkitt's Lymphoma	GDSC	VVTTPDLT	DEG_SCF_FBW7_1	171:178	Mutation rewiring degron network	0.3056
p.T179I	SIDM01710	Squamous Cell Lung Carcinoma	GDSC	VVTTPDLT	DEG_SCF_FBW7_1	171:178	Mutation rewiring degron network	0.3056
p.T170K	SIDM00855	Other Sarcomas	GDSC	VVTTPDLT	DEG_SCF_FBW7_1	171:178	Mutation rewiring degron network	0.3056
p.T170K	SIDM00656	Burkitt's Lymphoma	GDSC	VVTTPDLT	DEG_SCF_FBW7_1	171:178	Mutation rewiring degron network	0.3056
p.T170K	SIDM00633	Breast Carcinoma	GDSC	VVTTPDLT	DEG_SCF_FBW7_1	171:178	Mutation rewiring degron network	0.3056
p.T170K	SIDM00654	Small Cell Lung Carcinoma	GDSC	VVTTPDLT	DEG_SCF_FBW7_1	171:178	Mutation rewiring degron network	0.3056
p.T170K	SIDM00210	Ovarian Carcinoma	GDSC	VVTTPDLT	DEG_SCF_FBW7_1	171:178	Mutation rewiring degron network	0.3056
p.T170K	SIDM00878	Breast Carcinoma	GDSC	VVTTPDLT	DEG_SCF_FBW7_1	171:178	Mutation rewiring degron network	0.3056
p.T170K	SIDM00048	Non-Small Cell Lung Carcinoma	GDSC	VVTTPDLT	DEG_SCF_FBW7_1	171:178	Mutation rewiring degron network	0.3056
p.T170K	SIDM00254	Neuroblastoma	GDSC	VVTTPDLT	DEG_SCF_FBW7_1	171:178	Mutation rewiring degron network	0.3056
p.T170K	SIDM00309	Mesothelioma	GDSC	VVTTPDLT	DEG_SCF_FBW7_1	171:178	Mutation rewiring degron network	0.3056
p.T170K	SIDM00844	Burkitt's Lymphoma	GDSC	VVTTPDLT	DEG_SCF_FBW7_1	171:178	Mutation rewiring degron network	0.3056
p.T170K	SIDM00032	Bladder Carcinoma	GDSC	VVTTPDLT	DEG_SCF_FBW7_1	171:178	Mutation rewiring degron network	0.3056
p.T170K	SIDM01133	Other Solid Cancers	GDSC	VVTTPDLT	DEG_SCF_FBW7_1	171:178	Mutation rewiring degron network	0.3056
p.T170K	SIDM01072	Squamous Cell Lung Carcinoma	GDSC	VVTTPDLT	DEG_SCF_FBW7_1	171:178	Mutation rewiring degron network	0.3056
p.T170K	SIDM00863	Burkitt's Lymphoma	GDSC	VVTTPDLT	DEG_SCF_FBW7_1	171:178	Mutation rewiring degron network	0.3056
p.T170K	SIDM01229	Neuroblastoma	GDSC	VVTTPDLT	DEG_SCF_FBW7_1	171:178	Mutation rewiring degron network	0.3056
p.T170K	SIDM00641	Burkitt's Lymphoma	GDSC	VVTTPDLT	DEG_SCF_FBW7_1	171:178	Mutation rewiring degron network	0.3056
p.T170K	SIDM01664	Prostate Carcinoma	GDSC	VVTTPDLT	DEG_SCF_FBW7_1	171:178	Mutation rewiring degron network	0.3056
p.T170K	SIDM01710	Squamous Cell Lung Carcinoma	GDSC	VVTTPDLT	DEG_SCF_FBW7_1	171:178	Mutation rewiring degron network	0.3056
p.E216K	SIDM00291	Melanoma	GDSC	LLTPEPS	DEG_SCF_FBW7_1	212:218	Mutation altering degron motif	0.591
p.E216K	SIDM01433	Kidney Carcinoma	GDSC	LLTPEPS	DEG_SCF_FBW7_1	212:218	Mutation altering degron motif	0.591
p.E216K	HMV-II	skin	COSMIC	LLTPEPS	DEG_SCF_FBW7_1	212:218	Mutation altering degron motif	0.591
p.V171A	SIDM00660	Colorectal Carcinoma	GDSC	VVTTPDLT	DEG_SCF_FBW7_1	171:178	Mutation altering degron motif	0.6936
p.V171A	ACH-000985	Colon/Colorectal Cancer	CCLE	VVTTPDLT	DEG_SCF_FBW7_1	171:178	Mutation altering degron motif	0.6936
p.V171A	LS-411N	large intestine	COSMIC	VVTTPDLT	DEG_SCF_FBW7_1	171:178	Mutation altering degron motif	0.6936
p.P175T	SIDM00364	B-Lymphoblastic Leukemia	GDSC	VVTTPDLT	DEG_SCF_FBW7_1	171:178	Mutation altering degron motif	0.7031
p.P175T	SIDM00164	Biliary Tract Carcinoma	GDSC	VVTTPDLT	DEG_SCF_FBW7_1	171:178	Mutation altering degron motif	0.7031
p.P175T	ACH-000209	Bile Duct Cancer	CCLE	VVTTPDLT	DEG_SCF_FBW7_1	171:178	Mutation altering degron motif	0.7031
p.P175T	ACH-002059	Leukemia	CCLE	VVTTPDLT	DEG_SCF_FBW7_1	171:178	Mutation altering degron motif	0.7031
p.P175T	P30-OHK	haematopoietic and lymphoid tissue	COSMIC	VVTTPDLT	DEG_SCF_FBW7_1	171:178	Mutation altering degron motif	0.7031
p.S236F	SIDM00444	Esophageal Carcinoma	GDSC	VESTS	DEG_SPOP_SBC_1	240:244	Mutation rewiring degron network	0.2222
p.S236F	OACM5-1	oesophagus	COSMIC	VESTS	DEG_SPOP_SBC_1	240:244	Mutation rewiring degron network	0.2222
p.T138M	SIDM00220	Ovarian Carcinoma	GDSC	ASTTT	DEG_SPOP_SBC_1	134:138	Mutation altering degron motif	0.7423
p.T138M	ACH-000962	Ovarian Cancer	CCLE	ASTTT	DEG_SPOP_SBC_1	134:138	Mutation altering degron motif	0.7423
p.T138M	ACH-001145	Ovarian Cancer	CCLE	ASTTT	DEG_SPOP_SBC_1	134:138	Mutation altering degron motif	0.7423
p.T138M	OC-314	ovary	COSMIC	ASTTT	DEG_SPOP_SBC_1	134:138	Mutation altering degron motif	0.7423
p.D246E	ACH-000700	Lung Cancer	CCLE	VESTS	DEG_SPOP_SBC_1	240:244	Mutation rewiring degron network	0.2778
p.P182S	ACH-002069	Bone Cancer	CCLE	VVTTPDLT	DEG_SCF_FBW7_1	171:178	Mutation rewiring degron network	0.2222

DegronMD: protein-targeted degradation, mutation and drug response to degrons

TIMD4

UniProt ID: Q96H15

Entrez ID: 91937

Protein name: T-cell immunoglobulin and mucin domain-containing protein 4 (TIMD-4) (T-cell immunoglobulin mucin receptor 4) (TIM-4) (T-cell membrane protein 4)

External links: UniprotKB HGNC RefSeq COSMIC

Data table is loading....

Kaplan plot for TIMD4 in