DegronMD - Q96RK0(CIC)

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.A669V	TCGA-AD-6964	COAD	TCGA	PVSST	DEG_SPOP_SBC_1	678:682	Mutation rewiring degron network	0.0833
p.A669V	DO8360	COAD	ICGC	PVSST	DEG_SPOP_SBC_1	678:682	Mutation rewiring degron network	0.0833
p.R1277C	TCGA-BR-4184	STAD	TCGA	PSSSS	DEG_SPOP_SBC_1	1270:1274	Mutation rewiring degron network	0.25
p.R1277C	DO38328	STAD	ICGC	PSSSS	DEG_SPOP_SBC_1	1270:1274	Mutation rewiring degron network	0.25
p.S1267N	TCGA-CM-5861	COAD	TCGA	PSSSS	DEG_SPOP_SBC_1	1270:1274	Mutation rewiring degron network	0.25
p.S1267N	DO224971	BRCA	ICGC	PSSSS	DEG_SPOP_SBC_1	1270:1274	Mutation rewiring degron network	0.25
p.S1267N	DO52554	BRCA	ICGC	PSSSS	DEG_SPOP_SBC_1	1270:1274	Mutation rewiring degron network	0.25
p.S1267N	DO7918	COAD	ICGC	PSSSS	DEG_SPOP_SBC_1	1270:1274	Mutation rewiring degron network	0.25
p.F1095V	TCGA-D7-A6EY	STAD	TCGA	APTSS	DEG_SPOP_SBC_1	1101:1105	Mutation rewiring degron network	0.1667
p.F1095V	DO50118	STAD	ICGC	APTSS	DEG_SPOP_SBC_1	1101:1105	Mutation rewiring degron network	0.1667
p.P1135L	TCGA-DU-6407	LGG	TCGA	VATST	DEG_SPOP_SBC_1	1122:1126	Mutation rewiring degron network	0.0833
p.P1135L	DO22295	LGG	ICGC	VATST	DEG_SPOP_SBC_1	1122:1126	Mutation rewiring degron network	0.0833
p.S1104F	TCGA-EE-A181	SKCM	TCGA	APTSS	DEG_SPOP_SBC_1	1101:1105	Mutation altering degron motif	0.7982
p.R863C	TCGA-EE-A29D	SKCM	TCGA	APTTS	DEG_SPOP_SBC_1	857:861	Mutation rewiring degron network	0.2778
p.R863C	TCGA-EE-A29D	SKCM	TCGA	PGTST	DEG_SPOP_SBC_1	868:872	Mutation rewiring degron network	0.1944
p.R863C	DO38123	SKCM	ICGC	APTTS	DEG_SPOP_SBC_1	857:861	Mutation rewiring degron network	0.2778
p.R863C	DO38123	SKCM	ICGC	PGTST	DEG_SPOP_SBC_1	868:872	Mutation rewiring degron network	0.1944
p.R340W	TCGA-FI-A2D5	UCEC	TCGA	PGSSS	DEG_SPOP_SBC_1	331:335	Mutation rewiring degron network	0.1944
p.R340W	DO41331	UCEC	ICGC	PGSSS	DEG_SPOP_SBC_1	331:335	Mutation rewiring degron network	0.1944
p.R340W	SIDM00789	Colorectal Carcinoma	GDSC	PGSSS	DEG_SPOP_SBC_1	331:335	Mutation rewiring degron network	0.1944
p.R340W	HCT-15	large intestine	COSMIC	PGSSS	DEG_SPOP_SBC_1	331:335	Mutation rewiring degron network	0.1944
p.G1280W	TCGA-FS-A1ZQ	SKCM	TCGA	PSSSS	DEG_SPOP_SBC_1	1270:1274	Mutation rewiring degron network	0.1667
p.G1280W	DO37442	SKCM	ICGC	PSSSS	DEG_SPOP_SBC_1	1270:1274	Mutation rewiring degron network	0.1667
p.P1270H	TCGA-G2-A2EJ	BLCA	TCGA	PSSSS	DEG_SPOP_SBC_1	1270:1274	Mutation altering degron motif	0.7694
p.P1270H	DO554	BLCA	ICGC	PSSSS	DEG_SPOP_SBC_1	1270:1274	Mutation altering degron motif	0.7694
p.S335F	TCGA-GN-A8LK	SKCM	TCGA	PGSSS	DEG_SPOP_SBC_1	331:335	Mutation altering degron motif	0.9093
p.S335F	DO51259	SKCM	ICGC	PGSSS	DEG_SPOP_SBC_1	331:335	Mutation altering degron motif	0.9093
p.F864L	TCGA-KQ-A41N	BLCA	TCGA	APTTS	DEG_SPOP_SBC_1	857:861	Mutation rewiring degron network	0.25
p.F864L	TCGA-KQ-A41N	BLCA	TCGA	PGTST	DEG_SPOP_SBC_1	868:872	Mutation rewiring degron network	0.2222
p.F864L	DO223588	BLCA	ICGC	APTTS	DEG_SPOP_SBC_1	857:861	Mutation rewiring degron network	0.25
p.F864L	DO223588	BLCA	ICGC	PGTST	DEG_SPOP_SBC_1	868:872	Mutation rewiring degron network	0.2222
p.S543L	TCGA-KU-A6H7	HNSC	TCGA	PASSS	DEG_SPOP_SBC_1	539:543	Mutation altering degron motif	0.7667
p.S543L	DO52089	HNSC	ICGC	PASSS	DEG_SPOP_SBC_1	539:543	Mutation altering degron motif	0.7667
p.G525C	TCGA-XF-A9SI	BLCA	TCGA	APSSS	DEG_SPOP_SBC_1	531:535	Mutation rewiring degron network	0.1667
p.G525C	DO51914	BLCA	ICGC	APSSS	DEG_SPOP_SBC_1	531:535	Mutation rewiring degron network	0.1667
p.G525V	TCGA-XF-A9SI	BLCA	TCGA	APSSS	DEG_SPOP_SBC_1	531:535	Mutation rewiring degron network	0.1667
p.G525V	DO51914	BLCA	ICGC	APSSS	DEG_SPOP_SBC_1	531:535	Mutation rewiring degron network	0.1667
p.N1102Y	DO51866	BLCA	ICGC	APTSS	DEG_SPOP_SBC_1	1101:1105	Mutation altering degron motif	0.7059
p.E1095Q	DO456	BLCA	ICGC	APTSS	DEG_SPOP_SBC_1	1101:1105	Mutation rewiring degron network	0.1667
p.P540T	DO225048	BRCA	ICGC	PASSS	DEG_SPOP_SBC_1	539:543	Mutation altering degron motif	0.7031
p.S1103T	DO228483	BRCA	ICGC	APTSS	DEG_SPOP_SBC_1	1101:1105	Mutation altering degron motif	0.7116
p.S1103T	DO229005	COCA	ICGC	APTSS	DEG_SPOP_SBC_1	1101:1105	Mutation altering degron motif	0.7116
p.R1124W	DO222490	BTCA	ICGC	VATST	DEG_SPOP_SBC_1	1122:1126	Mutation altering degron motif	0.8634
p.R1124W	DO223732	CESC	ICGC	VATST	DEG_SPOP_SBC_1	1122:1126	Mutation altering degron motif	0.8634
p.R1124W	DO48508	LGG	ICGC	VATST	DEG_SPOP_SBC_1	1122:1126	Mutation altering degron motif	0.8634
p.R1124W	DO50211	LGG	ICGC	VATST	DEG_SPOP_SBC_1	1122:1126	Mutation altering degron motif	0.8634
p.R1124W	DO50147	LGG	ICGC	VATST	DEG_SPOP_SBC_1	1122:1126	Mutation altering degron motif	0.8634
p.R1124W	DO50252	LGG	ICGC	VATST	DEG_SPOP_SBC_1	1122:1126	Mutation altering degron motif	0.8634
p.R1124W	DO22163	LGG	ICGC	VATST	DEG_SPOP_SBC_1	1122:1126	Mutation altering degron motif	0.8634
p.R1124W	DO22199	LGG	ICGC	VATST	DEG_SPOP_SBC_1	1122:1126	Mutation altering degron motif	0.8634
p.R1124W	DO22315	LGG	ICGC	VATST	DEG_SPOP_SBC_1	1122:1126	Mutation altering degron motif	0.8634
p.R1124W	DO223698	LGG	ICGC	VATST	DEG_SPOP_SBC_1	1122:1126	Mutation altering degron motif	0.8634
p.R1124W	DO44585	LGG	ICGC	VATST	DEG_SPOP_SBC_1	1122:1126	Mutation altering degron motif	0.8634
p.A687T	DO222427	BTCA	ICGC	PVSST	DEG_SPOP_SBC_1	678:682	Mutation rewiring degron network	0.1944
p.A687T	DO229544	UTCA	ICGC	PVSST	DEG_SPOP_SBC_1	678:682	Mutation rewiring degron network	0.1944
p.A687T	SIDM00083	Glioblastoma	GDSC	PVSST	DEG_SPOP_SBC_1	678:682	Mutation rewiring degron network	0.1944
p.A687T	ACH-000273	Brain Cancer	CCLE	PVSST	DEG_SPOP_SBC_1	678:682	Mutation rewiring degron network	0.1944
p.R1122Q	DO222817	BTCA	ICGC	VATST	DEG_SPOP_SBC_1	1122:1126	Mutation altering degron motif	0.7329
p.R1122Q	DO40996	UCEC	ICGC	VATST	DEG_SPOP_SBC_1	1122:1126	Mutation altering degron motif	0.7329
p.R1122Q	DO41199	UCEC	ICGC	VATST	DEG_SPOP_SBC_1	1122:1126	Mutation altering degron motif	0.7329
p.N674S	DO223357	CLLE	ICGC	PVSST	DEG_SPOP_SBC_1	678:682	Mutation rewiring degron network	0.2222
p.R1130H	DO233634	GACA	ICGC	VATST	DEG_SPOP_SBC_1	1122:1126	Mutation rewiring degron network	0.2222
p.R1130H	DO38201	STAD	ICGC	VATST	DEG_SPOP_SBC_1	1122:1126	Mutation rewiring degron network	0.2222
p.R1130H	DO40808	UCEC	ICGC	VATST	DEG_SPOP_SBC_1	1122:1126	Mutation rewiring degron network	0.2222
p.R1124Q	DO50238	LGG	ICGC	VATST	DEG_SPOP_SBC_1	1122:1126	Mutation altering degron motif	0.7329
p.R1124Q	DO50198	LGG	ICGC	VATST	DEG_SPOP_SBC_1	1122:1126	Mutation altering degron motif	0.7329
p.R1124Q	DO50156	LGG	ICGC	VATST	DEG_SPOP_SBC_1	1122:1126	Mutation altering degron motif	0.7329
p.R1124Q	DO22324	LGG	ICGC	VATST	DEG_SPOP_SBC_1	1122:1126	Mutation altering degron motif	0.7329
p.R1124Q	ACH-000984	Endometrial/Uterine Cancer	CCLE	VATST	DEG_SPOP_SBC_1	1122:1126	Mutation altering degron motif	0.7329
p.R1110W	DO50210	LGG	ICGC	APTSS	DEG_SPOP_SBC_1	1101:1105	Mutation rewiring degron network	0.1944
p.R1110W	DO50188	LGG	ICGC	APTSS	DEG_SPOP_SBC_1	1101:1105	Mutation rewiring degron network	0.1944
p.R1110W	DO22634	LGG	ICGC	APTSS	DEG_SPOP_SBC_1	1101:1105	Mutation rewiring degron network	0.1944
p.R1110W	DO22199	LGG	ICGC	APTSS	DEG_SPOP_SBC_1	1101:1105	Mutation rewiring degron network	0.1944
p.R1110W	DO223674	LGG	ICGC	APTSS	DEG_SPOP_SBC_1	1101:1105	Mutation rewiring degron network	0.1944
p.R1110W	DO223698	LGG	ICGC	APTSS	DEG_SPOP_SBC_1	1101:1105	Mutation rewiring degron network	0.1944
p.R1111W	DO50196	LGG	ICGC	APTSS	DEG_SPOP_SBC_1	1101:1105	Mutation rewiring degron network	0.1667
p.R1111W	DO50252	LGG	ICGC	APTSS	DEG_SPOP_SBC_1	1101:1105	Mutation rewiring degron network	0.1667
p.R1111W	DO22235	LGG	ICGC	APTSS	DEG_SPOP_SBC_1	1101:1105	Mutation rewiring degron network	0.1667
p.R1111W	DO223690	LGG	ICGC	APTSS	DEG_SPOP_SBC_1	1101:1105	Mutation rewiring degron network	0.1667
p.R1111W	DO223696	LGG	ICGC	APTSS	DEG_SPOP_SBC_1	1101:1105	Mutation rewiring degron network	0.1667
p.P1112L	DO50177	LGG	ICGC	APTSS	DEG_SPOP_SBC_1	1101:1105	Mutation rewiring degron network	0.1389
p.P1112L	DO50177	LGG	ICGC	VATST	DEG_SPOP_SBC_1	1122:1126	Mutation rewiring degron network	0.0556
p.N1136I	DO50173	LGG	ICGC	VATST	DEG_SPOP_SBC_1	1122:1126	Mutation substituting flanking lysine	0.1667
p.P1112S	DO50146	LGG	ICGC	APTSS	DEG_SPOP_SBC_1	1101:1105	Mutation rewiring degron network	0.1389
p.P1112S	DO50146	LGG	ICGC	VATST	DEG_SPOP_SBC_1	1122:1126	Mutation rewiring degron network	0.0556
p.P1112S	DO22109	LGG	ICGC	APTSS	DEG_SPOP_SBC_1	1101:1105	Mutation rewiring degron network	0.1389
p.P1112S	DO22109	LGG	ICGC	VATST	DEG_SPOP_SBC_1	1122:1126	Mutation rewiring degron network	0.0556
p.R1122P	DO50252	LGG	ICGC	VATST	DEG_SPOP_SBC_1	1122:1126	Mutation altering degron motif	0.7512
p.F1119C	DO22496	LGG	ICGC	VATST	DEG_SPOP_SBC_1	1122:1126	Mutation rewiring degron network	0.25
p.N1114S	DO22443	LGG	ICGC	APTSS	DEG_SPOP_SBC_1	1101:1105	Mutation rewiring degron network	0.0833
p.N1114S	DO22443	LGG	ICGC	VATST	DEG_SPOP_SBC_1	1122:1126	Mutation rewiring degron network	0.1111
p.F1119L	DO48603	LGG	ICGC	VATST	DEG_SPOP_SBC_1	1122:1126	Mutation rewiring degron network	0.25
p.R1111Q	DO44595	LGG	ICGC	APTSS	DEG_SPOP_SBC_1	1101:1105	Mutation rewiring degron network	0.1667
p.V676L	DO228813	LICA	ICGC	PVSST	DEG_SPOP_SBC_1	678:682	Mutation rewiring degron network	0.2778
p.V1127F	DO228952	LICA	ICGC	VATST	DEG_SPOP_SBC_1	1122:1126	Mutation rewiring degron network	0.3056
p.G553C	DO228952	LICA	ICGC	PASSS	DEG_SPOP_SBC_1	539:543	Mutation rewiring degron network	0.0556
p.S1125I	DO228971	LICA	ICGC	VATST	DEG_SPOP_SBC_1	1122:1126	Mutation altering degron motif	0.7341
p.S1125I	DO229034	LICA	ICGC	VATST	DEG_SPOP_SBC_1	1122:1126	Mutation altering degron motif	0.7341
p.A330S	DO229018	LICA	ICGC	PGSSS	DEG_SPOP_SBC_1	331:335	Mutation rewiring degron network	0.3056
p.V1278F	DO229015	LICA	ICGC	PSSSS	DEG_SPOP_SBC_1	1270:1274	Mutation rewiring degron network	0.2222
p.R1277L	DO229026	LICA	ICGC	PSSSS	DEG_SPOP_SBC_1	1270:1274	Mutation rewiring degron network	0.25
p.R1277L	DO229041	LICA	ICGC	PSSSS	DEG_SPOP_SBC_1	1270:1274	Mutation rewiring degron network	0.25
p.S325I	DO229036	LICA	ICGC	PGSSS	DEG_SPOP_SBC_1	331:335	Mutation rewiring degron network	0.1667
p.R863L	DO229041	LICA	ICGC	APTTS	DEG_SPOP_SBC_1	857:861	Mutation rewiring degron network	0.2778
p.R863L	DO229041	LICA	ICGC	PGTST	DEG_SPOP_SBC_1	868:872	Mutation rewiring degron network	0.1944
p.A879S	DO229041	LICA	ICGC	PGTST	DEG_SPOP_SBC_1	868:872	Mutation rewiring degron network	0.1389
p.D537G	DO27334	LUSC	ICGC	APSSS	DEG_SPOP_SBC_1	531:535	Mutation rewiring degron network	0.2778
p.D537G	DO27334	LUSC	ICGC	PASSS	DEG_SPOP_SBC_1	539:543	Mutation rewiring degron network	0.2778
p.R688Q	DO228271	MALY	ICGC	PVSST	DEG_SPOP_SBC_1	678:682	Mutation rewiring degron network	0.1667
p.R688Q	ACH-000806	Lymphoma	CCLE	PVSST	DEG_SPOP_SBC_1	678:682	Mutation rewiring degron network	0.1667
p.S1274T	DO228861	MALY	ICGC	PSSSS	DEG_SPOP_SBC_1	1270:1274	Mutation altering degron motif	0.6005
p.T322I	DO220899	MELA	ICGC	PGSSS	DEG_SPOP_SBC_1	331:335	Mutation rewiring degron network	0.0833
p.R545Q	DO229139	NKTL	ICGC	APSSS	DEG_SPOP_SBC_1	531:535	Mutation rewiring degron network	0.0556
p.R545Q	DO229139	NKTL	ICGC	PASSS	DEG_SPOP_SBC_1	539:543	Mutation rewiring degron network	0.2778
p.R523H	DO35083	PACA	ICGC	APSSS	DEG_SPOP_SBC_1	531:535	Mutation rewiring degron network	0.1111
p.L341P	DO51474	PACA	ICGC	PGSSS	DEG_SPOP_SBC_1	331:335	Mutation rewiring degron network	0.1667
p.R340Q	DO228138	PBCA	ICGC	PGSSS	DEG_SPOP_SBC_1	331:335	Mutation rewiring degron network	0.1944
p.S333N	DO232761	PBCA	ICGC	PGSSS	DEG_SPOP_SBC_1	331:335	Mutation altering degron motif	0.818
p.C336R	DO232519	PBCA	ICGC	PGSSS	DEG_SPOP_SBC_1	331:335	Mutation rewiring degron network	0.3056
p.S1094F	DO229446	SKCA	ICGC	APTSS	DEG_SPOP_SBC_1	1101:1105	Mutation rewiring degron network	0.1389
p.P858L	DO218863	SKCA	ICGC	APTTS	DEG_SPOP_SBC_1	857:861	Mutation altering degron motif	0.6471
p.S1103F	DO37444	SKCM	ICGC	APTSS	DEG_SPOP_SBC_1	1101:1105	Mutation altering degron motif	0.7982
p.A851E	DO229259	THCA	ICGC	APTTS	DEG_SPOP_SBC_1	857:861	Mutation rewiring degron network	0.1667
p.V684M	DO229234	THCA	ICGC	PVSST	DEG_SPOP_SBC_1	678:682	Mutation rewiring degron network	0.2778
p.R1130C	DO42280	UCEC	ICGC	VATST	DEG_SPOP_SBC_1	1122:1126	Mutation rewiring degron network	0.2222
p.R1099C	DO41823	UCEC	ICGC	APTSS	DEG_SPOP_SBC_1	1101:1105	Mutation rewiring degron network	0.2778
p.R1099C	ACH-000398	Lymphoma	CCLE	APTSS	DEG_SPOP_SBC_1	1101:1105	Mutation rewiring degron network	0.2778
p.G1098E	DO41361	UCEC	ICGC	APTSS	DEG_SPOP_SBC_1	1101:1105	Mutation rewiring degron network	0.25
p.V672L	SIDM01964	Esophageal Carcinoma	GDSC	PVSST	DEG_SPOP_SBC_1	678:682	Mutation rewiring degron network	0.1667
p.S1104T	SIDM00615	Hepatocellular Carcinoma	GDSC	APTSS	DEG_SPOP_SBC_1	1101:1105	Mutation altering degron motif	0.6005
p.S1104T	SIDM01028	Esophageal Squamous Cell Carcinoma	GDSC	APTSS	DEG_SPOP_SBC_1	1101:1105	Mutation altering degron motif	0.6005
p.S1104T	SIDM00060	Ovarian Carcinoma	GDSC	APTSS	DEG_SPOP_SBC_1	1101:1105	Mutation altering degron motif	0.6005
p.S1104T	SIDM00618	Hepatocellular Carcinoma	GDSC	APTSS	DEG_SPOP_SBC_1	1101:1105	Mutation altering degron motif	0.6005
p.S1104T	SIDM00603	Head and Neck Carcinoma	GDSC	APTSS	DEG_SPOP_SBC_1	1101:1105	Mutation altering degron motif	0.6005
p.S1104T	SIDM01611	Endometrial Carcinoma	GDSC	APTSS	DEG_SPOP_SBC_1	1101:1105	Mutation altering degron motif	0.6005
p.S1104T	SIDM01690	Plasma Cell Myeloma	GDSC	APTSS	DEG_SPOP_SBC_1	1101:1105	Mutation altering degron motif	0.6005
p.S1097P	SIDM00845	Burkitt's Lymphoma	GDSC	APTSS	DEG_SPOP_SBC_1	1101:1105	Mutation rewiring degron network	0.2222
p.S1097P	SIDM01519	Head and Neck Carcinoma	GDSC	APTSS	DEG_SPOP_SBC_1	1101:1105	Mutation rewiring degron network	0.2222
p.V1278I	SIDM00781	Colorectal Carcinoma	GDSC	PSSSS	DEG_SPOP_SBC_1	1270:1274	Mutation rewiring degron network	0.2222
p.V1278I	SIDM00780	Colorectal Carcinoma	GDSC	PSSSS	DEG_SPOP_SBC_1	1270:1274	Mutation rewiring degron network	0.2222
p.V1278I	SNU-C2B	large intestine	COSMIC	PSSSS	DEG_SPOP_SBC_1	1270:1274	Mutation rewiring degron network	0.2222
p.P1102L	SIDM00217	Colorectal Carcinoma	GDSC	APTSS	DEG_SPOP_SBC_1	1101:1105	Mutation altering degron motif	0.6471
p.L552V	SIDM01764	Non-Small Cell Lung Carcinoma	GDSC	PASSS	DEG_SPOP_SBC_1	539:543	Mutation rewiring degron network	0.0833
p.P683L	ACH-000131	Non-Cancerous	CCLE	PVSST	DEG_SPOP_SBC_1	678:682	Mutation rewiring degron network	0.3056
p.R340S	ACH-000260	Neuroblastoma	CCLE	PGSSS	DEG_SPOP_SBC_1	331:335	Mutation rewiring degron network	0.1944
p.E326K	ACH-000462	Leukemia	CCLE	PGSSS	DEG_SPOP_SBC_1	331:335	Mutation rewiring degron network	0.1944
p.C521Y	ACH-000777	Esophageal Cancer	CCLE	APSSS	DEG_SPOP_SBC_1	531:535	Mutation rewiring degron network	0.0556
p.A874G	ACH-000867	Lung Cancer	CCLE	PGTST	DEG_SPOP_SBC_1	868:872	Mutation rewiring degron network	0.2778
p.R340L	ACH-000870	Lung Cancer	CCLE	PGSSS	DEG_SPOP_SBC_1	331:335	Mutation rewiring degron network	0.1944
p.P857H	ACH-000907	Kidney Cancer	CCLE	APTTS	DEG_SPOP_SBC_1	857:861	Mutation altering degron motif	0.7694
p.V672M	ACH-000941	Endometrial/Uterine Cancer	CCLE	PVSST	DEG_SPOP_SBC_1	678:682	Mutation rewiring degron network	0.1667
p.V672M	ACH-000954	Endometrial/Uterine Cancer	CCLE	PVSST	DEG_SPOP_SBC_1	678:682	Mutation rewiring degron network	0.1667
p.A1125V	ACH-000942	Leukemia	CCLE	VATST	DEG_SPOP_SBC_1	1122:1126	Mutation altering degron motif	0.6936
p.P850L	ACH-000953	Leukemia	CCLE	APTTS	DEG_SPOP_SBC_1	857:861	Mutation rewiring degron network	0.1389
p.T1127P	ACH-000956	Prostate Cancer	CCLE	VATST	DEG_SPOP_SBC_1	1122:1126	Mutation rewiring degron network	0.3056
p.A543T	ACH-000967	Colon/Colorectal Cancer	CCLE	PASSS	DEG_SPOP_SBC_1	539:543	Mutation altering degron motif	0.7139
p.K669R	ACH-000978	Endometrial/Uterine Cancer	CCLE	PVSST	DEG_SPOP_SBC_1	678:682	Mutation rewiring degron network	0.0833
p.N1114D	ACH-000990	Endometrial/Uterine Cancer	CCLE	APTSS	DEG_SPOP_SBC_1	1101:1105	Mutation rewiring degron network	0.0833
p.N1114D	ACH-000990	Endometrial/Uterine Cancer	CCLE	VATST	DEG_SPOP_SBC_1	1122:1126	Mutation rewiring degron network	0.1111
p.N1102D	ACH-000998	Colon/Colorectal Cancer	CCLE	APTSS	DEG_SPOP_SBC_1	1101:1105	Mutation altering degron motif	0.6932
p.N1102D	CW-2	large intestine	COSMIC	APTSS	DEG_SPOP_SBC_1	1101:1105	Mutation altering degron motif	0.6932
p.R333H	ACH-000999	Colon/Colorectal Cancer	CCLE	PGSSS	DEG_SPOP_SBC_1	331:335	Mutation altering degron motif	0.8244
p.G1274S	ACH-000999	Colon/Colorectal Cancer	CCLE	PSSSS	DEG_SPOP_SBC_1	1270:1274	Mutation altering degron motif	0.6993
p.G1274S	SNU-1040	large intestine	COSMIC	PSSSS	DEG_SPOP_SBC_1	1270:1274	Mutation altering degron motif	0.6993
p.V1276I	SNU-C2B	large intestine	COSMIC	PSSSS	DEG_SPOP_SBC_1	1270:1274	Mutation rewiring degron network	0.2778
p.R1104Q	NCI-SNU-16	stomach	COSMIC	APTSS	DEG_SPOP_SBC_1	1101:1105	Mutation altering degron motif	0.7329

DegronMD: protein-targeted degradation, mutation and drug response to degrons

CIC

UniProt ID: Q96RK0

Entrez ID: 23152

Protein name: Protein capicua homolog

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for CIC in