p.P363L | TCGA-18-3410 | LUSC | TCGA | DSGKST | DEG_SCF_TRCP1_1 | 373:378 | Mutation rewiring degron network | 0.0556 |
p.E372K | TCGA-22-1016 | LUSC | TCGA | DSGKST | DEG_SCF_TRCP1_1 | 373:378 | Mutation blocking phosphorylation signal | 0.75 |
p.D381H | TCGA-29-2429 | OV | TCGA | DSGKST | DEG_SCF_TRCP1_1 | 373:378 | Mutation rewiring degron network | 0.25 |
p.P293S | TCGA-46-6025 | LUSC | TCGA | APEARVLPK | DEG_SIAH_1 | 295:303 | Mutation rewiring degron network | 0.2778 |
p.P293S | TCGA-EB-A553 | SKCM | TCGA | APEARVLPK | DEG_SIAH_1 | 295:303 | Mutation rewiring degron network | 0.2778 |
p.L382I | TCGA-86-8668 | LUAD | TCGA | DSGKST | DEG_SCF_TRCP1_1 | 373:378 | Mutation rewiring degron network | 0.2222 |
p.P110S | TCGA-AA-3663 | COAD | TCGA | LMGTPSGT | DEG_SCF_FBW7_1 | 104:111 | Mutation altering degron motif | 0.6752 |
p.V101M | TCGA-AR-A0TU | BRCA | TCGA | LMGTPSGT | DEG_SCF_FBW7_1 | 104:111 | Mutation rewiring degron network | 0.25 |
p.E386Q | TCGA-BA-5152 | HNSC | TCGA | DSGKST | DEG_SCF_TRCP1_1 | 373:378 | Mutation rewiring degron network | 0.1111 |
p.E386Q | TCGA-OL-A97C | BRCA | TCGA | DSGKST | DEG_SCF_TRCP1_1 | 373:378 | Mutation rewiring degron network | 0.1111 |
p.T292A | TCGA-CG-5721 | STAD | TCGA | APEARVLPK | DEG_SIAH_1 | 295:303 | Mutation rewiring degron network | 0.25 |
p.A378V | TCGA-DU-6392 | LGG | TCGA | DSGKST | DEG_SCF_TRCP1_1 | 373:378 | Mutation altering degron motif | 0.6936 |
p.E372Q | TCGA-EA-A43B | CESC | TCGA | DSGKST | DEG_SCF_TRCP1_1 | 373:378 | Mutation blocking phosphorylation signal | 0.75 |
p.E372Q | TCGA-ZF-A9R7 | BLCA | TCGA | DSGKST | DEG_SCF_TRCP1_1 | 373:378 | Mutation blocking phosphorylation signal | 0.75 |
p.V118G | TCGA-FI-A2D5 | UCEC | TCGA | LMGTPSGT | DEG_SCF_FBW7_1 | 104:111 | Mutation rewiring degron network | 0.1389 |
p.R383W | TCGA-SJ-A6ZI | UCEC | TCGA | DSGKST | DEG_SCF_TRCP1_1 | 373:378 | Mutation rewiring degron network | 0.1944 |
p.P108L | TCGA-UF-A7J9 | HNSC | TCGA | LMGTPSGT | DEG_SCF_FBW7_1 | 104:111 | Mutation altering degron motif | 0.7582 |
p.P108L | DO8264 | COAD | ICGC | LMGTPSGT | DEG_SCF_FBW7_1 | 104:111 | Mutation altering degron motif | 0.7582 |
p.T287P | DO48437 | BLCA | ICGC | EPPAEVTPS | DEG_SIAH_1 | 269:277 | Mutation rewiring degron network | 0.0556 |
p.T287P | DO48437 | BLCA | ICGC | APEARVLPK | DEG_SIAH_1 | 295:303 | Mutation rewiring degron network | 0.1111 |
p.E369Q | DO219640 | BRCA | ICGC | DSGKST | DEG_SCF_TRCP1_1 | 373:378 | Mutation rewiring degron network | 0.2222 |
p.E369Q | DO14393 | HNSC | ICGC | DSGKST | DEG_SCF_TRCP1_1 | 373:378 | Mutation rewiring degron network | 0.2222 |
p.D266G | DO7798 | COAD | ICGC | EPPAEVTPS | DEG_SIAH_1 | 269:277 | Mutation rewiring degron network | 0.25 |
p.G263D | DO233207 | GACA | ICGC | EPPAEVTPS | DEG_SIAH_1 | 269:277 | Mutation rewiring degron network | 0.1667 |
p.E311K | DO44425 | HNSC | ICGC | APEARVLPK | DEG_SIAH_1 | 295:303 | Mutation rewiring degron network | 0.1111 |
p.S112Y | DO19028 | KIRC | ICGC | LMGTPSGT | DEG_SCF_FBW7_1 | 104:111 | Mutation rewiring degron network | 0.3056 |
p.A305V | DO22237 | LGG | ICGC | APEARVLPK | DEG_SIAH_1 | 295:303 | Mutation rewiring degron network | 0.2778 |
p.T363S | DO232028 | LICA | ICGC | DSGKST | DEG_SCF_TRCP1_1 | 373:378 | Mutation rewiring degron network | 0.0556 |
p.P270T | DO229035 | LICA | ICGC | EPPAEVTPS | DEG_SIAH_1 | 269:277 | Mutation altering degron motif | 0.7031 |
p.H286Q | DO229037 | LICA | ICGC | EPPAEVTPS | DEG_SIAH_1 | 269:277 | Mutation rewiring degron network | 0.0833 |
p.H286Q | DO229037 | LICA | ICGC | APEARVLPK | DEG_SIAH_1 | 295:303 | Mutation rewiring degron network | 0.0833 |
p.V265M | DO23316 | LINC | ICGC | EPPAEVTPS | DEG_SIAH_1 | 269:277 | Mutation rewiring degron network | 0.2222 |
p.L304I | DO25669 | LUAD | ICGC | APEARVLPK | DEG_SIAH_1 | 295:303 | Mutation rewiring degron network | 0.3056 |
p.T277M | DO25426 | LUAD | ICGC | EPPAEVTPS | DEG_SIAH_1 | 269:277 | Mutation altering degron motif | 0.7423 |
p.P290L | DO26456 | LUSC | ICGC | APEARVLPK | DEG_SIAH_1 | 295:303 | Mutation rewiring degron network | 0.1944 |
p.D303H | DO30580 | OV | ICGC | APEARVLPK | DEG_SIAH_1 | 295:303 | Mutation altering degron motif | 0.7688 |
p.P108S | DO51266 | SKCM | ICGC | LMGTPSGT | DEG_SCF_FBW7_1 | 104:111 | Mutation altering degron motif | 0.6752 |
p.T275A | DO38192 | STAD | ICGC | EPPAEVTPS | DEG_SIAH_1 | 269:277 | Mutation altering degron motif | 0.6028 |
p.R366W | DO219784 | UCEC | ICGC | DSGKST | DEG_SCF_TRCP1_1 | 373:378 | Mutation rewiring degron network | 0.1389 |
p.S311L | DO40978 | UCEC | ICGC | APEARVLPK | DEG_SIAH_1 | 295:303 | Mutation rewiring degron network | 0.1111 |
p.S311L | DO52402 | UCEC | ICGC | APEARVLPK | DEG_SIAH_1 | 295:303 | Mutation rewiring degron network | 0.1111 |
p.K384N | DO41758 | UCEC | ICGC | DSGKST | DEG_SCF_TRCP1_1 | 373:378 | Mutation substituting flanking lysine | 0.2778 |
p.V101G | DO41331 | UCEC | ICGC | LMGTPSGT | DEG_SCF_FBW7_1 | 104:111 | Mutation rewiring degron network | 0.25 |
p.R370K | SIDM00193 | Colorectal Carcinoma | GDSC | DSGKST | DEG_SCF_TRCP1_1 | 373:378 | Mutation rewiring degron network | 0.25 |
p.R370K | SNU-81 | large intestine | COSMIC | DSGKST | DEG_SCF_TRCP1_1 | 373:378 | Mutation rewiring degron network | 0.25 |
p.S284L | SIDM01041 | Esophageal Carcinoma | GDSC | EPPAEVTPS | DEG_SIAH_1 | 269:277 | Mutation rewiring degron network | 0.1389 |
p.S284L | FLO-1 | oesophagus | COSMIC | EPPAEVTPS | DEG_SIAH_1 | 269:277 | Mutation rewiring degron network | 0.1389 |
p.D381N | SIDM00767 | Small Cell Lung Carcinoma | GDSC | DSGKST | DEG_SCF_TRCP1_1 | 373:378 | Mutation rewiring degron network | 0.25 |
p.D381N | NCI-H187 | lung | COSMIC | DSGKST | DEG_SCF_TRCP1_1 | 373:378 | Mutation rewiring degron network | 0.25 |
p.E295Q | SIDM00837 | Colorectal Carcinoma | GDSC | APEARVLPK | DEG_SIAH_1 | 295:303 | Mutation altering degron motif | 0.6744 |
p.E295Q | SW48 | large intestine | COSMIC | APEARVLPK | DEG_SIAH_1 | 295:303 | Mutation altering degron motif | 0.6744 |
p.I263M | SIDM00534 | Colorectal Carcinoma | GDSC | EPPAEVTPS | DEG_SIAH_1 | 269:277 | Mutation rewiring degron network | 0.1667 |
p.I263M | SIDM00118 | Colorectal Carcinoma | GDSC | EPPAEVTPS | DEG_SIAH_1 | 269:277 | Mutation rewiring degron network | 0.1667 |
p.I263M | HT-115 | large intestine | COSMIC | EPPAEVTPS | DEG_SIAH_1 | 269:277 | Mutation rewiring degron network | 0.1667 |
p.I263M | HCC2998 | large intestine | COSMIC | EPPAEVTPS | DEG_SIAH_1 | 269:277 | Mutation rewiring degron network | 0.1667 |
p.Q274R | SIDM00192 | Colorectal Carcinoma | GDSC | EPPAEVTPS | DEG_SIAH_1 | 269:277 | Mutation altering degron motif | 0.7329 |
p.T378K | ACH-000137 | Brain Cancer | CCLE | DSGKST | DEG_SCF_TRCP1_1 | 373:378 | Mutation altering degron motif | 0.8417 |
p.T378K | 8-MG-BA | central nervous system | COSMIC | DSGKST | DEG_SCF_TRCP1_1 | 373:378 | Mutation altering degron motif | 0.8417 |
p.R121C | ACH-000198 | Leukemia | CCLE | LMGTPSGT | DEG_SCF_FBW7_1 | 104:111 | Mutation rewiring degron network | 0.0556 |
p.R121C | EoL-1-cell | haematopoietic and lymphoid tissue | COSMIC | LMGTPSGT | DEG_SCF_FBW7_1 | 104:111 | Mutation rewiring degron network | 0.0556 |
p.S306C | ACH-000916 | Lung Cancer | CCLE | APEARVLPK | DEG_SIAH_1 | 295:303 | Mutation blocking phosphorylation signal | 0.6944 |
p.S306C | NCI-H1573 | lung | COSMIC | APEARVLPK | DEG_SIAH_1 | 295:303 | Mutation blocking phosphorylation signal | 0.6944 |
p.E278Q | ACH-000958 | Colon/Colorectal Cancer | CCLE | EPPAEVTPS | DEG_SIAH_1 | 269:277 | Mutation rewiring degron network | 0.3056 |
p.E278Q | SW48 | large intestine | COSMIC | EPPAEVTPS | DEG_SIAH_1 | 269:277 | Mutation rewiring degron network | 0.3056 |
p.D364N | ACH-001136 | Lung Cancer | CCLE | DSGKST | DEG_SCF_TRCP1_1 | 373:378 | Mutation rewiring degron network | 0.0833 |
p.D364N | NCI-H187 | lung | COSMIC | DSGKST | DEG_SCF_TRCP1_1 | 373:378 | Mutation rewiring degron network | 0.0833 |
p.S267L | ACH-001500 | Esophageal Cancer | CCLE | EPPAEVTPS | DEG_SIAH_1 | 269:277 | Mutation rewiring degron network | 0.2778 |
p.S267L | FLO-1 | oesophagus | COSMIC | EPPAEVTPS | DEG_SIAH_1 | 269:277 | Mutation rewiring degron network | 0.2778 |
p.D269N | NCI-H187 | lung | COSMIC | EPPAEVTPS | DEG_SIAH_1 | 269:277 | Mutation altering degron motif | 0.6932 |
p.I296V | Sarc9371 | bone | COSMIC | APEARVLPK | DEG_SIAH_1 | 295:303 | Mutation altering degron motif | 0.7076 |
p.T283K | 8-MG-BA | central nervous system | COSMIC | EPPAEVTPS | DEG_SIAH_1 | 269:277 | Mutation rewiring degron network | 0.1667 |
p.K119T | MOG-G-CCM | central nervous system | COSMIC | LMGTPSGT | DEG_SCF_FBW7_1 | 104:111 | Mutation substituting flanking lysine | 0.2222 |
p.R297K | SNU-81 | large intestine | COSMIC | APEARVLPK | DEG_SIAH_1 | 295:303 | Mutation altering degron motif | 0.7237 |
p.A111T | LoVo | large intestine | COSMIC | LMGTPSGT | DEG_SCF_FBW7_1 | 104:111 | Mutation altering degron motif | 0.7139 |
p.R108Q | 22RV1 | prostate | COSMIC | LMGTPSGT | DEG_SCF_FBW7_1 | 104:111 | Mutation altering degron motif | 0.7329 |
p.D308N | NCI-H187 | lung | COSMIC | APEARVLPK | DEG_SIAH_1 | 295:303 | Mutation substituting flanking lysine | 0.3056 |