Gene: Cdc42

Basic information

Tag Content
Uniprot ID A0A0G2JSM8
Entrez ID 64465
Genbank protein ID EDL80835.1
Genbank nucleotide ID XM_008764287.2
Ensembl protein ID ENSRNOP00000018118
Ensembl nucleotide ID ENSRNOG00000013536
Gene name Cell division control protein 42 homolog
Gene symbol Cdc42
Organism Rattus norvegicus
NCBI taxa ID 10116
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MQTIKCVVVG DGAVGKTCLL ISYTTNKFPS EYVPTVFDNY AVTVMIGGEP YTLGLFDTAG 60
QEDYDRLRPL SYPQTDVFLV CFSVVSPSSF ENVKEKWVPE ITHHCPKTPF LLVGTQIDLR 120
DDPSTIEKLA KNKQKPITPE TAEKLARDLK AVKYVECSAL TQRGLKNVFD EAILAALEPP 180
ETQPKRKCCI F 191

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologCDC42403934P60952Canis lupus familiarisPredictionMore>>
1:1 orthologCDC42102188638A0A452EIX9Capra hircusPredictionMore>>
1:1 orthologCDC42998P60953Homo sapiensPredictionMore>>
1:1 orthologCdc4212540P60766CPO,CLPMus musculusPublicationMore>>
1:1 orthologCDC42456609A0A2I3TL10Pan troglodytesPredictionMore>>
1:1 orthologCDC42780428F2Z5W2Sus scrofaPredictionMore>>
1:1 orthologCdc4264465A0A0G2JSM8Rattus norvegicusPredictionMore>>
1:1 orthologcdc42336839Q6PFU4Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005525 GTP binding
GO:0003924 GTPase activity
GO:0051301 cell division
GO:0007264 small GTPase mediated signal transduction

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0131 Cell cycle
KW-0132 Cell division
KW-0342 GTP-binding
KW-0547 Nucleotide-binding
KW-1267 Proteomics identification
KW-1185 Reference proteome

Interpro

InterPro ID InterPro Term
IPR037874 Cdc42
IPR027417 P-loop_NTPase
IPR005225 Small_GTP-bd_dom
IPR001806 Small_GTPase
IPR003578 Small_GTPase_Rho

PROSITE

PROSITE ID PROSITE Term
PS51420 RHO

Pfam

Pfam ID Pfam Term
PF00071 Ras