| Tag | Content |
|---|---|
| Uniprot ID | A0A0G2K0J9 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSRNOP00000071478 |
| Ensembl nucleotide ID | ENSRNOG00000060599 |
| Gene name | Gamma-aminobutyric acid receptor subunit beta-3 |
| Gene symbol | Gabrb3 |
| Organism | Rattus norvegicus |
| NCBI taxa ID | 10116 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | APPLGARGAA WHDPGNMSFV KETVDKLLKG YDIRLRPDFG GPPVCVGMNI DIASIDMVSE 60 VNMDYTLTMY FQQYWRDKRL AYSGIPLNLT LDNRVADQLW VPDTYFLNDK KSFVHGVTVK 120 NRMIRLHPDG TVLYGLRITT TAACMMDLRR YPLDEQNCTL EIESYGYTTD DIEFYWRGGD 180 KAVTGVERIE LPQFSIVEHR LVSRNVVFAT GAYPRLSLSF RLKRNIGYFI LQTYMPSILI 240 TILSWVSFWI NYDASAARVA LGITTVLTMT TINTHLRETL PKIPYVKAID MYLMGCFVFV 300 FLALLEYAFV NYIFFGRGPQ RQKKLAEKTA KAKNDRSKSE INRVDAHGNI LLAPMDVHNE 360 MNEVAGSVGD TRNSAISFDN SGIQYRKQSM PKEGHGRYMG DRSIPHKKTH LRRRSSQLKI 420 KIPDLTDVNA IDRWSRIVFP FTFSLFNLVY WLYYVN 456 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | GABRB3 | A0A452FJH3 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | GABRB3 | 2562 | P28472 | CL/P | Homo sapiens | Publication | More>> | |
| 1:1 ortholog | Gabrb3 | 14402 | P63080 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | GABRB3 | 453265 | A0A2I3THQ1 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | A0A4X1UB00 | Sus scrofa | Prediction | More>> | ||||
| 1:1 ortholog | Gabrb3 | A0A0G2K0J9 | Rattus norvegicus | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:1902711 | GABA-A receptor complex |
| GO:0098982 | GABA-ergic synapse |
| GO:0005887 | integral component of plasma membrane |
| GO:0098794 | postsynapse |
| GO:0004890 | GABA-A receptor activity |
| GO:0022851 | GABA-gated chloride ion channel activity |
| GO:0042802 | identical protein binding |
| GO:1904315 | transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential |
| GO:0071420 | cellular response to histamine |
| GO:0090102 | cochlea development |
| GO:0007214 | gamma-aminobutyric acid signaling pathway |
| GO:0060080 | inhibitory postsynaptic potential |
| GO:1904862 | inhibitory synapse assembly |
| GO:0060119 | inner ear receptor cell development |
| GO:0060384 | innervation |
| GO:0043524 | negative regulation of neuron apoptotic process |
| GO:0060021 | roof of mouth development |
| GO:0007605 | sensory perception of sound |
| PROSITE ID | PROSITE Term |
|---|---|
| PS00236 | NEUROTR_ION_CHANNEL |