| Tag | Content |
|---|---|
| Uniprot ID | A0A2I3THQ1; A0A2J8KLJ7; |
| Entrez ID | 453265 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_003314570.1 |
| Ensembl protein ID | ENSPTRP00000088796 |
| Ensembl nucleotide ID | ENSPTRG00000006831 |
| Gene name | Gamma-aminobutyric acid type A receptor beta3 subunit |
| Gene symbol | GABRB3 |
| Organism | Pan troglodytes |
| NCBI taxa ID | 9598 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MWGLAGGRLF GIFSAPVLVA VVCCAQSVND PGNMSFVKET VDKLLKGYDI RLRPDFGGPP 60 VCVGMNIDIA SIDMVSEVNM DYTLTMYFQQ YWRDKRLAYS GIPLNLTLDN RVADQLWVPD 120 TYFLNDKKSF VHGVTVKNRM IRLHPDGTVL YGLRITTTAA CMMDLRRYPL DEQNCTLEIE 180 SYGYTTDDIE FYWRGGDKAV TGVERIELPQ FSIVEHRLVS RNVVFATGAY PRLSLSFRLK 240 RNIGYFILQT YMPSILITIL SWVSFWINYD ASAARVALGI TTVLTMTTIN THLRETLPKI 300 PYVKAIDMYL MGCFVFVFLA LLEYAFVNYI FFGRGPQRQK KLAEKTAKAK NDRSKSESNR 360 VDAHGNILLT SLEVHNEMNE VAGGIGDTRN SAISFDNSGI QYRKQSMPRE GHGRFLGDRS 420 LPHKKTHLRR RSSQLKIKIP DLTDVNAIDR WSRIVFPFTF SLFNLVYWLY YVN 473 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | GABRB3 | A0A452FJH3 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | GABRB3 | 2562 | P28472 | CL/P | Homo sapiens | Publication | More>> | |
| 1:1 ortholog | Gabrb3 | 14402 | P63080 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | GABRB3 | 453265 | A0A2I3THQ1 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | A0A4X1UB00 | Sus scrofa | Prediction | More>> | ||||
| 1:1 ortholog | Gabrb3 | A0A0G2K0J9 | Rattus norvegicus | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0016021 | integral component of membrane |
| GO:0005886 | plasma membrane |
| GO:0005230 | extracellular ligand-gated ion channel activity |
| GO:0004890 | GABA-A receptor activity |
| PROSITE ID | PROSITE Term |
|---|---|
| PS00236 | NEUROTR_ION_CHANNEL |