| Tag | Content |
|---|---|
| Uniprot ID | A0A452FJH3 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSCHIP00000024243 |
| Ensembl nucleotide ID | ENSCHIG00000021468 |
| Gene name | Gamma-aminobutyric acid type A receptor beta3 subunit |
| Gene symbol | GABRB3 |
| Organism | Capra hircus |
| NCBI taxa ID | 9925 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | CWQTCQSTQI DYTLTMYFQQ YWRDKRLAYS GIPLNLTLDN RVADQLWVPD TYFLNDKKSF 60 VHGVTVKNRM IRLHPDGTVL YGLRITTTAA CMMDLRRYPL DEQNCTLEIE SYGYTTDDIE 120 FYWRGGDKAV TGVERIELPQ FSIVEHRLVS RNVVFATGAY PRLSLSFRLK RNIGYFILQT 180 YMPSILITIL SWVSFWINYD ASAARVALGI TTVLTMTTIN THLRETLPKI PYVKAIDMYL 240 MGCFVFVFLA LLEYAFVNYI FFGRGPQRQK KLAEKNAKAK NDRSKGDSNR VDAHGNILLT 300 SLEVHNEMNE VAGGVGDTRN SARSFDNSGI QYRKQSMPRE GHGRHMDRSV PHKKTHLRRR 360 SSQLKIKIPD LTDVNAIDRW SRIVFPFTFS LFNLVYWLYY VN 402 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | GABRB3 | A0A452FJH3 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | GABRB3 | 2562 | P28472 | CL/P | Homo sapiens | Publication | More>> | |
| 1:1 ortholog | Gabrb3 | 14402 | P63080 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | GABRB3 | 453265 | A0A2I3THQ1 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | A0A4X1UB00 | Sus scrofa | Prediction | More>> | ||||
| 1:1 ortholog | Gabrb3 | A0A0G2K0J9 | Rattus norvegicus | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0016021 | integral component of membrane |
| GO:0005886 | plasma membrane |
| GO:0005230 | extracellular ligand-gated ion channel activity |
| GO:0004890 | GABA-A receptor activity |
| PROSITE ID | PROSITE Term |
|---|---|
| PS00236 | NEUROTR_ION_CHANNEL |