| Tag | Content |
|---|---|
| Uniprot ID | A0A0R4ITI2 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSDARP00000140311 |
| Ensembl nucleotide ID | ENSDARG00000100475 |
| Gene name | Fibroblast growth factor |
| Gene symbol | fgf10b |
| Organism | Danio rerio |
| NCBI taxa ID | 7955 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MRSTMRRWTV SKSVSACWSV CVVYFLAVSV TCRGACLRVS SSASTSTSGR HARSYVHLQG 60 DVRQRRLFSF QKFFLRIGKD GKVNGTKSED DPYSILEITS VDVGVVAIRG LGSNLYLAIS 120 KKGELFGVRN YGTNCRLKER IEENGYNTYA SAKWKNNKRQ IFVSLSAHGR PLRGRKNRRK 180 NTATHFLPMV V 191 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | FGF10 | 612454 | J9NVD5 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | FGF10 | 102174339 | A0A142I1Y0 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | FGF10 | 100052655 | F7CND4 | Equus caballus | Prediction | More>> | ||
| 1:1 ortholog | FGF10 | 2255 | O15520 | Homo sapiens | Publication | More>> | ||
| 1:1 ortholog | Fgf10 | 14165 | O35565 | CPO | E11.5, E11.75, E12.5, E13.5, E14.5, E15.5, E16.5 | Mus musculus | Publication | More>> |
| 1:1 ortholog | FGF10 | 471553 | A0A2I3T2G6 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | FGF10 | F1SMG2 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | FGF10 | 100342802 | G1SVA6 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | Fgf10 | 25443 | P70492 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | fgf10b | A0A0R4ITI2 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005737 | cytoplasm |
| GO:0005615 | extracellular space |
| GO:0042056 | chemoattractant activity |
| GO:0005104 | fibroblast growth factor receptor binding |
| GO:0008083 | growth factor activity |
| GO:0005111 | type 2 fibroblast growth factor receptor binding |
| GO:0009887 | animal organ morphogenesis |
| GO:0030154 | cell differentiation |
| GO:0071696 | ectodermal placode development |
| GO:0008543 | fibroblast growth factor receptor signaling pathway |
| GO:0060173 | limb development |
| GO:0001889 | liver development |
| GO:0071599 | otic vesicle development |
| GO:0031016 | pancreas development |
| GO:0050918 | positive chemotaxis |
| GO:0090263 | positive regulation of canonical Wnt signaling pathway |
| GO:0008284 | positive regulation of cell population proliferation |
| GO:0010634 | positive regulation of epithelial cell migration |
| GO:0050679 | positive regulation of epithelial cell proliferation |
| GO:0070374 | positive regulation of ERK1 and ERK2 cascade |
| GO:0010628 | positive regulation of gene expression |
| GO:0001934 | positive regulation of protein phosphorylation |
| GO:0030334 | regulation of cell migration |
| GO:0061033 | secretion by lung epithelial cell involved in lung growth |
| GO:0042060 | wound healing |
| Keyword ID | Keyword Term |
|---|---|
| KW-1185 | Reference proteome |
| PROSITE ID | PROSITE Term |
|---|---|
| PS00247 | HBGF_FGF |
| Pfam ID | Pfam Term |
|---|---|
| PF00167 | FGF |