| Tag | Content |
|---|---|
| Uniprot ID | A0A0R4IYE7 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSDARP00000140230 |
| Ensembl nucleotide ID | ENSDARG00000104618 |
| Gene name | Gremlin 1b |
| Gene symbol | grem1b |
| Organism | Danio rerio |
| NCBI taxa ID | 7955 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MGRFTDRFFS KISPGRSSST LTVMPASCAS SSGWILCAVL LSSALLWCPT ESKRNRGAIP 60 HPDKNTPNES SRSPQQQESA SGSRARSRGS EEVLESSQEA LHVTERRYLK RDWCKTQPLK 120 QTIHEEGCIS RTIINRFCYG QCNSFYIPRH VRREEGAFQS CSFCKPKRFT TMSFTLSCPD 180 QQPPTRKKRV QRVKQCRCIS IELD 204 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | GREM1 | 539079 | A2VE87 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | GREM1 | A0A452E4N7 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | GREM1 | 26585 | O60565 | CL/P | Homo sapiens | Publication | More>> | |
| 1:1 ortholog | Grem1 | 23892 | O70326 | Mus musculus | Prediction | More>> | ||
| 1:1 ortholog | GREM1 | A0A287ABW3 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | GREM1 | 100342066 | G1TUM4 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | Grem1 | 50566 | O35793 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | grem1b | A0A0R4IYE7 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005615 | extracellular space |
| GO:0036122 | BMP binding |
| GO:0048018 | receptor ligand activity |
| GO:0009887 | animal organ morphogenesis |
| GO:0038098 | sequestering of BMP from receptor via BMP binding |
| Pfam ID | Pfam Term |
|---|---|
| PF03045 | DAN |