Gene: GREM1

Basic information

Tag Content
Uniprot ID A2VE87
Entrez ID 539079
Genbank protein ID AAI33626.1
Genbank nucleotide ID NM_001082450.1
Ensembl protein ID
Ensembl nucleotide ID
Gene name Gremlin
Gene symbol GREM1
Organism Bos taurus
NCBI taxa ID 9913
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MSRTAYTVGA LLLLLGTLLP AAEGKKKGSQ GAIPPPDKAQ HNDSEQTQSP QQPGSRNRGR 60
GQGRGTAMPG EEVLESSQEA LHVTERKYLK RDWCKTQPLK QTIHEEGCNS RTIINRFCYG 120
QCNSFYIPRH IRKEEGSFQS CSFCKPKKFT TMMVTLNCPE LQPPTKKKRV TRVKQCRCIS 180
IDLD 184

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologGREM1539079A2VE87Bos taurusPredictionMore>>
1:1 orthologGREM1A0A452E4N7Capra hircusPredictionMore>>
1:1 orthologGREM126585O60565CL/PHomo sapiensPublicationMore>>
1:1 orthologGrem123892O70326Mus musculusPredictionMore>>
1:1 orthologGREM1A0A287ABW3Sus scrofaPredictionMore>>
1:1 orthologGREM1100342066G1TUM4Oryctolagus cuniculusPredictionMore>>
1:1 orthologGrem150566O35793Rattus norvegicusPredictionMore>>
1:1 orthologgrem1bA0A0R4IYE7Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005615 extracellular space
GO:0005125 cytokine activity

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0202 Cytokine
KW-1015 Disulfide bond
KW-0964 Secreted
KW-0732 Signal

Interpro

InterPro ID InterPro Term
IPR006207 Cys_knot_C
IPR029034 Cystine-knot_cytokine
IPR004133 DAN
IPR017159 Gremlin-1/2

PROSITE

PROSITE ID PROSITE Term

Pfam

Pfam ID Pfam Term
PF03045 DAN