| Tag | Content |
|---|---|
| Uniprot ID | A0A287A115 |
| Entrez ID | 102162332 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_005663090.2 |
| Ensembl protein ID | ENSSSCP00000037603 |
| Ensembl nucleotide ID | ENSSSCG00000039568 |
| Gene name | Snail family transcriptional repressor 2 |
| Gene symbol | SNAI2 |
| Organism | Sus scrofa |
| NCBI taxa ID | 9823 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MPRSFLVKKH FNASKKPNYS ELDTHTVIVS PYLYESYPMP VIPQPEILSS RAYSPIAVWT 60 SAAPFHAPLP NGLSPLSGYP PPLGRVSPPP PSDTSSKDHS GSESPVSDEE ERLQSKLSDP 120 HAIEAEKFQC NLCSKTYSTF SGLGKHKQLH CDAQSRKSFS CKYCDKEYVS LGALKMHIRT 180 HTLPCVCKIC GKAFSRPWLL QGHIRTHTGE KPFSCPHCSR AFADRSNLRA HLQTHSDVKK 240 YQCKNCSKTF SRMSLLHKHE ESGCCVAH 268 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | SNAI2 | 520631 | Q3MHQ4 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | SNAI2 | F1PTM6 | Canis lupus familiaris | Prediction | More>> | |||
| 1:1 ortholog | SNAI2 | 102178744 | A0A452FYL7 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | SNAI2 | 100050060 | F6R5C0 | Equus caballus | Prediction | More>> | ||
| 1:1 ortholog | SNAI2 | 6591 | O43623 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Snai2 | 20583 | P97469 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | SNAI2 | 464169 | H2QW52 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | SNAI2 | 102162332 | A0A287A115 | Sus scrofa | Prediction | More>> | ||
| 1:1 ortholog | SNAI2 | 100346095 | G1T2X3 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | Snai2 | 25554 | O08954 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | snai2 | 494038 | Q5PQY5 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005737 | cytoplasm |
| GO:0000790 | nuclear chromatin |
| GO:0005634 | nucleus |
| GO:0003682 | chromatin binding |
| GO:0003677 | DNA binding |
| GO:0003700 | DNA-binding transcription factor activity |
| GO:0001227 | DNA-binding transcription repressor activity, RNA polymerase II-specific |
| GO:0070888 | E-box binding |
| GO:0060536 | cartilage morphogenesis |
| GO:0003273 | cell migration involved in endocardial cushion formation |
| GO:0071364 | cellular response to epidermal growth factor stimulus |
| GO:0071479 | cellular response to ionizing radiation |
| GO:0035921 | desmosome disassembly |
| GO:0003198 | epithelial to mesenchymal transition involved in endocardial cushion formation |
| GO:0060429 | epithelium development |
| GO:2000811 | negative regulation of anoikis |
| GO:0090090 | negative regulation of canonical Wnt signaling pathway |
| GO:0006933 | negative regulation of cell adhesion involved in substrate-bound cell migration |
| GO:0032331 | negative regulation of chondrocyte differentiation |
| GO:0043518 | negative regulation of DNA damage response, signal transduction by p53 class mediator |
| GO:2001240 | negative regulation of extrinsic apoptotic signaling pathway in absence of ligand |
| GO:1902230 | negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage |
| GO:0010839 | negative regulation of keratinocyte proliferation |
| GO:2000647 | negative regulation of stem cell proliferation |
| GO:0010957 | negative regulation of vitamin D biosynthetic process |
| GO:0070563 | negative regulation of vitamin D receptor signaling pathway |
| GO:0014032 | neural crest cell development |
| GO:0007219 | Notch signaling pathway |
| GO:0001649 | osteoblast differentiation |
| GO:0043473 | pigmentation |
| GO:0030335 | positive regulation of cell migration |
| GO:0045600 | positive regulation of fat cell differentiation |
| GO:0035066 | positive regulation of histone acetylation |
| GO:2000810 | regulation of bicellular tight junction assembly |
| GO:0060693 | regulation of branching involved in salivary gland morphogenesis |
| GO:0032642 | regulation of chemokine production |
| GO:0045667 | regulation of osteoblast differentiation |
| GO:0006355 | regulation of transcription, DNA-templated |
| GO:0060021 | roof of mouth development |
| GO:0007605 | sensory perception of sound |
| GO:0050872 | white fat cell differentiation |
| Pfam ID | Pfam Term |
|---|---|
| PF00096 | zf-C2H2 |