Gene: FOXG1

Basic information

Tag Content
Uniprot ID A0A287A2J5
Entrez ID
Genbank protein ID
Genbank nucleotide ID
Ensembl protein ID ENSSSCP00000037951
Ensembl nucleotide ID ENSSSCG00000033761
Gene name Forkhead box G1
Gene symbol FOXG1
Organism Sus scrofa
NCBI taxa ID 9823
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MLDMGDRKEV KMIPKSSFSI NSLVPEAVQN DNHHPSHGHH NSHHPQHHHH HHHHHHPPPP 60
APQPPPPPQQ QPPPPPPQAP QPPQARGAPA TDDDKGPQQL LLPPPPPPPA AALDGAKADG 120
LGGKGEPGGG PGELAPVGPD EKEKGAGAGG EEKKGAGEGG KDGEGGKEGE KKNGKYEKPP 180
FSYNALIMMA IRQSPEKRLT LNGIYEFIMK NFPYYRENKQ GWQNSIRHNL SLNKCFVKVP 240
RHYDDPGKGN YWMLDPSSDD VFIGGTTGKL RRRSTTSRAK LAFKRGARLT STGLTFMDRA 300
GSLYWPMSPF LSLHHPRASS TLSYNGTTSA YPSHPMPYSS VLTQNSLGNN HSFSTANGLS 360
VDRLVNGEIP YATHHLTAAA LAASVPCGLS VPCSGTYSLN PCSVNLLAGQ TSYFFPHVPH 420
PSMTSQSSTS MSARAASSST SPQAPSTLPC ESLRPSLPSF TTGLSGGLSD YFTHQNQGSS 480
SNPLIH 486

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologFOXG1A0A452FP40Capra hircusPredictionMore>>
1:1 orthologFOXG12290P55316Homo sapiensPublicationMore>>
1:1 orthologFoxg115228Q60987Mus musculusPredictionMore>>
1:1 orthologFOXG1467416H2R9E1Pan troglodytesPredictionMore>>
1:1 orthologFOXG1A0A287A2J5Sus scrofaPredictionMore>>
1:1 orthologFoxg124370Q00939Rattus norvegicusPredictionMore>>
1:1 orthologfoxg1a30274Q568V0Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005634 nucleus
GO:0003700 DNA-binding transcription factor activity
GO:0043565 sequence-specific DNA binding
GO:0016199 axon midline choice point recognition
GO:0009953 dorsal/ventral pattern formation
GO:0042472 inner ear morphogenesis
GO:0045665 negative regulation of neuron differentiation
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0048664 neuron fate determination
GO:0045787 positive regulation of cell cycle
GO:0002052 positive regulation of neuroblast proliferation
GO:0045666 positive regulation of neuron differentiation
GO:0021852 pyramidal neuron migration
GO:0007346 regulation of mitotic cell cycle

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0238 DNA-binding
KW-0539 Nucleus
KW-1185 Reference proteome

Interpro

InterPro ID InterPro Term
IPR001766 Fork_head_dom
IPR018122 TF_fork_head_CS_1
IPR030456 TF_fork_head_CS_2
IPR036388 WH-like_DNA-bd_sf
IPR036390 WH_DNA-bd_sf

PROSITE

PROSITE ID PROSITE Term
PS00657 FORK_HEAD_1
PS00658 FORK_HEAD_2
PS50039 FORK_HEAD_3

Pfam

Pfam ID Pfam Term
PF00250 Forkhead