| Tag | Content |
|---|---|
| Uniprot ID | H2R9E1; A0A2J8QKX0; |
| Entrez ID | 467416 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_016925947.1; XM_016925948.1; |
| Ensembl protein ID | ENSPTRP00000052740 |
| Ensembl nucleotide ID | ENSPTRG00000030783 |
| Gene name | Forkhead box G1 |
| Gene symbol | FOXG1 |
| Organism | Pan troglodytes |
| NCBI taxa ID | 9598 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MLDMGDRKEV KMIPKSSFSI NSLVPEAVQN DNHHASHGHH NSHHPQHHHH HHHHHHHPPP 60 PAPQPPPPPQ QQQPPPPPPP APQPPQTRGA PAADDDKGPQ QLLLPPPPPP PPAAALDGAK 120 ADGLGGKGEP GGGPGELAPV GPDEKEKGAG AGGEEKKGAG EGGKDGEGGK EGEKKNGKYE 180 KPPFSYNALI MMAIRQSPEK RLTLNGIYEF IMKNFPYYRE NKQGWQNSIR HNLSLNKCFV 240 KVPRHYDDPG KGNYWMLDPS SDDVFIGGTT GKLRRRSTTS RAKLAFKRGA RLTSTGLTFM 300 DRAGSLYWPM SPFLSLHHPR ASSTLSYNGT TSAYPSHPMP YSSVLTQNSL GNNHSFSTAN 360 GLSVDRLVNG EIPYATHHLT AAALAASVPC GLSVPCSGTY SLNPCSVNLL AGQTSYFFPH 420 VPHPSMTSQS STSMSARAAS SSTSPQAPST LPCESLRPSL PSFTTGLSGG LSDYFTHQNQ 480 GSSSNPLIH 489 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | FOXG1 | A0A452FP40 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | FOXG1 | 2290 | P55316 | Homo sapiens | Publication | More>> | ||
| 1:1 ortholog | Foxg1 | 15228 | Q60987 | Mus musculus | Prediction | More>> | ||
| 1:1 ortholog | FOXG1 | 467416 | H2R9E1 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | FOXG1 | A0A287A2J5 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | Foxg1 | 24370 | Q00939 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | foxg1a | 30274 | Q568V0 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005634 | nucleus |
| GO:0003700 | DNA-binding transcription factor activity |
| GO:0043565 | sequence-specific DNA binding |
| GO:0016199 | axon midline choice point recognition |
| GO:0009953 | dorsal/ventral pattern formation |
| GO:0042472 | inner ear morphogenesis |
| GO:0045665 | negative regulation of neuron differentiation |
| GO:0000122 | negative regulation of transcription by RNA polymerase II |
| GO:0048664 | neuron fate determination |
| GO:0045787 | positive regulation of cell cycle |
| GO:0002052 | positive regulation of neuroblast proliferation |
| GO:0045666 | positive regulation of neuron differentiation |
| GO:0021852 | pyramidal neuron migration |
| GO:0007346 | regulation of mitotic cell cycle |
| Pfam ID | Pfam Term |
|---|---|
| PF00250 | Forkhead |