Gene: FOXG1

Basic information

Tag Content
Uniprot ID A0A452FP40
Entrez ID
Genbank protein ID
Genbank nucleotide ID
Ensembl protein ID ENSCHIP00000026000
Ensembl nucleotide ID ENSCHIG00000022539
Gene name Forkhead box G1
Gene symbol FOXG1
Organism Capra hircus
NCBI taxa ID 9925
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MLDMGDRKEV KMIPKSSFSI NSLVPEAVQN DNHHASHGHH NSHHPQHHHH HHHHHHHPPP 60
PAPQPPPQQQ PPPPPPPPPP QAPQPPQARG APAADDDKGP QQLLLPPPPP PPPPAAALDG 120
AKADGLGGKG EPGGGPGELA PVGPDEKEKG AGAGGEEKKG AGEGGKDGEG GKEGEKKNGK 180
YEKPPFSYNA LIMMAIRQSP EKRLTLNGIY EFIMKNFPYY RENKQGWQNS IRHNLSLNKC 240
FVKVPRHYDD PGKGNYWMLD PSSDDVFIGG TTGKLRRRST TSRAKLAFKR GARLTSTGLT 300
FMDRAGSLYW PMSPFLSLHH PRASSTLSYN GTTSAYPSHP MPYSSVLTQN SLGNNHSFST 360
ANGLSVDRLV NGEIPYATHH LTAAALAASV PCGLSVPCSG TYSLNPCSVN LLAGQTSYFF 420
PHVPHPSMTS QSSTSMSARA ASSSTSPQAP STLPSSARQM GLSSMKICAT IPTSRPVPDV 480
ARRMRKKKTS GLEALLPQDR IGALRGGASQ SDGYRQNVGE PWDLKLCGRL KGGAEGEL 538

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologFOXG1A0A452FP40Capra hircusPredictionMore>>
1:1 orthologFOXG12290P55316Homo sapiensPublicationMore>>
1:1 orthologFoxg115228Q60987Mus musculusPredictionMore>>
1:1 orthologFOXG1467416H2R9E1Pan troglodytesPredictionMore>>
1:1 orthologFOXG1A0A287A2J5Sus scrofaPredictionMore>>
1:1 orthologFoxg124370Q00939Rattus norvegicusPredictionMore>>
1:1 orthologfoxg1a30274Q568V0Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005634 nucleus
GO:0003700 DNA-binding transcription factor activity
GO:0043565 sequence-specific DNA binding
GO:0045892 negative regulation of transcription, DNA-templated

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0238 DNA-binding
KW-0539 Nucleus
KW-1185 Reference proteome

Interpro

InterPro ID InterPro Term
IPR001766 Fork_head_dom
IPR018122 TF_fork_head_CS_1
IPR030456 TF_fork_head_CS_2
IPR036388 WH-like_DNA-bd_sf
IPR036390 WH_DNA-bd_sf

PROSITE

PROSITE ID PROSITE Term
PS00657 FORK_HEAD_1
PS00658 FORK_HEAD_2
PS50039 FORK_HEAD_3

Pfam

Pfam ID Pfam Term
PF00250 Forkhead