Gene: JARID2

Basic information

Tag Content
Uniprot ID A0A287AMW5; A0A286ZRY6;
Entrez ID
Genbank protein ID HDC11715.1
Genbank nucleotide ID
Ensembl protein ID ENSSSCP00000045247
Ensembl nucleotide ID ENSSSCG00000001061
Gene name Jumonji and AT-rich interaction domain containing 2
Gene symbol JARID2
Organism Sus scrofa
NCBI taxa ID 9823
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MSKERPKRNI IQKKYDDSDG IPWSEERVVR KVLYLSLKEF KNAQKRQHGE GIPGSLKTVN 60
GLLGNGQSKG LGPASEQSEN EKDDASQVSS TSNDVSSSDF EEGPSRKRPR LQAQRKFAQS 120
QPNSPSTTPV KIVEPLLPPP ATQISDLSKR KPKTEDFLTF LCLRGSPALP NSMVYFGSSQ 180
DEEDVEEEDD ETEDVKTAAN NASSSCQSTP RKGKTHKHVH NGHVFNGSSR SSREKEPVQK 240
HKSKEATPAK EKHSDPRADG RREQASASHP PAAPSTGSSA KGLAANHHHP PLHRSAQDLR 300
KQVSKVNGVT RMSSLGTSAT SAKKMREVRP SPSKTVKYTA TVTKGTVTYT KAKRELVKET 360
KPNHHKPSSA VNHTISGKTE SSNAKTRKQV LSLGGASKST GHAVNGLKVS GRLNPKSCTK 420
EVGGRQLREG LRNSKRRLEE APPADKPQSP PKKMKGAAGA AEGPGRKPAS AQAPAPAPAP 480
APAEKAPPGG HVKKEVPERS LERNRPKRAA AGKGPPGRQA HSKPDAPCEH RSTSQSEPLP 540
RPHEAAAKAE KGAGRAGWAA MDEIPVLRPS AKEFHDPLVY IESVRPQVEK YGMCRVIPPP 600
DWRPECKLND EMRFVTQIQH IHKLGRRWGP NVQRLACIKK HLRSQGITMD ELPLIGGCEL 660
DLACFFRLIN EMGGMQQVTD LKKWNKLADM LRIPKTAQDR LAKLQEAYCQ YLLSYDSLSP 720
EEHRRLEKEV LMEKESLERR KGPLEGHTEQ DYNRFHPLPR FEPKNGLING VAHRNGFRSK 780
LKEVGPAQLK TGRRRLFAQE KEVAKEEEED KGILSDFHKC IYKGRSVSLT TFYRTARNIM 840
NMCFSKEPAP AEIEQEYWRL VEEKDCHVAV HCGKVDTNTH GSGFPVGKSE PFSRHGWNLT 900
VLPNNTGSIL RHLGAVPGVT IPWLNIGMVF STSCWSRDQN HLPYIDYLHT GADCIWYCIP 960
AEEENKLEDV VHTLLQANGT PGLQMLESNV MISPEVLCRE GVKVHRAVQQ SGQFVVCFPG 1020
SFVSKVCCGY SVSETVHFAT TQWTSMGFET AKEMKRRHIA KPFSMEKLLY QIAQAEAKKE 1080
NGPTLSTISA LLDELRDTEL RQRRQLFEAG LHSSARYGSH DGGSAAPDGK KKPRKWLQLE 1140
TSERRCQVCQ HLCYLSMVVQ ENENVVFCLE CALRHVEKQK SCRGLKLMYR YDEEQIISLV 1200
NQICGKVSGK NGSIENCLGK PTPKRGPRKR ATVDVPPSRL APSSS 1245

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologJARID2478729A0A5F4DE24Canis lupus familiarisPredictionMore>>
1:1 orthologJARID2102184681A0A452DTS6Capra hircusPredictionMore>>
1:1 orthologJARID23720Q92833CPO,CL/PHomo sapiensPublicationMore>>
1:1 orthologJarid2G3UZT8E14.5, E15.5Mus musculusPredictionMore>>
1:1 orthologJARID2462450A0A2I3SRS8Pan troglodytesPredictionMore>>
1:1 orthologJARID2A0A287AMW5Sus scrofaPredictionMore>>
1:1 orthologJarid2681740M0RBV7Rattus norvegicusPredictionMore>>

Gene ontology

GO ID GO Term
GO:0035098 ESC/E(Z) complex
GO:0005739 mitochondrion
GO:0003682 chromatin binding
GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding
GO:0008134 transcription factor binding
GO:1990830 cellular response to leukemia inhibitory factor
GO:0001889 liver development
GO:0008285 negative regulation of cell population proliferation
GO:0031061 negative regulation of histone methylation
GO:0051574 positive regulation of histone H3-K9 methylation
GO:0048536 spleen development
GO:0048863 stem cell differentiation
GO:0048538 thymus development

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0539 Nucleus
KW-1185 Reference proteome
KW-0804 Transcription
KW-0805 Transcription regulation

Interpro

InterPro ID InterPro Term
IPR001606 ARID_dom
IPR036431 ARID_dom_sf
IPR003347 JmjC_dom
IPR003349 JmjN
IPR004198 Znf_C5HC2

PROSITE

PROSITE ID PROSITE Term
PS51011 ARID
PS51184 JMJC
PS51183 JMJN

Pfam

Pfam ID Pfam Term
PF01388 ARID
PF02373 JmjC
PF02375 JmjN
PF02928 zf-C5HC2