| Tag | Content |
|---|---|
| Uniprot ID | M0RBV7 |
| Entrez ID | 681740 |
| Genbank protein ID | EDL98180.1; EDL98179.1; |
| Genbank nucleotide ID | XM_017600708.1; XM_017587712.1; XM_017587711.1; XM_017600710.1; XM_017587713.1; XM_017600709.1; |
| Ensembl protein ID | ENSRNOP00000067055 |
| Ensembl nucleotide ID | ENSRNOG00000045918 |
| Gene name | Jumonji and AT-rich interaction domain-containing 2 |
| Gene symbol | Jarid2 |
| Organism | Rattus norvegicus |
| NCBI taxa ID | 10116 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MSKERPKRNI IQKKYDDSDG IPWSEERVVR KVLYLSLKEF KNAQKRQHGE GIAGSLKTVN 60 GLLGNDQSKA LGPASEQSEN EKDDASQVSS TSNDVSSSDF EEGPSRKRPR LQAQRKFAQS 120 QPNSPSTTPV KTVEPLLPPP ATHISDLSKR KPKTEDFLTF LCLRGSPALP NSMVYFGSSQ 180 DEEDVEEEDD ETEDVKTATN NASSSCQSTP RKGKSHKHVH NGHVFNGSNR SAREKEPAQK 240 HRGREATPGK EKHSEHRADG RREQASVAQP TANPPAGSST KGLAASHQPP PSHRSAQDSR 300 KQVSKVNGVT RMSSLGAGTN SAKKIREVRP SPSKTVKYTA TVTKGTVTYT KAKRELVKET 360 KPSHHKPSSA VNHTISGKSE SSNAKTRKQV LSLGGASTST APAASGLKAS SRLNPKSCTK 420 EVGGRQLREG LRNSKRRLEE AQQVDKQQSP PKKMKGTAGI AEAPGRKASA ASGEKSLLNG 480 HVKKEVPERS LERNRPKRAA AGKNMLGKQA HGKSEGTPCE NRSTSQPESS HKPHDPQGKP 540 EKGSGKSGWA AMDEIPVLRP SAKEFHDPLI YIESVRAQVE KYGMCRVIPP PDWRPECKLN 600 DEMRFVTQIQ HIHKLGRRWG PNVQRLACIK KHLRSQGITM DELPLIGGCE LDLACFFRLI 660 NEMGGMQQVT DLKKWNKLAD MLRIPKTAQD RLAKLQEAYC QYLLSYDSLS PEEHRRLEKE 720 VLMEKEILEK RKGPLEGHTE NDHHKFHSLP RFEPKNGLIH GVTPRNGFRS KLKEVGRAPL 780 KTGRRRLFAQ EKEVVKEEEE DKGVLDDFYK CIYKGRSVSL TTFYRTARNI MNMCFSKEPA 840 PAEIEQEYWR LVEEKDCHVA VHCGKVDTNT HGSGFPVGKS EPFSRHGWNL TVLPNNTGSI 900 LRHLGAVPGV TIPWLNIGMV FSTSCWSRDQ NHLPYIDYLH TGADCIWYCI PAEEENKLED 960 VVHTLLQGNG TPGLQMLESN VMISPEVLCK EGIKVHRTVQ QSGQFVVCFP GSFVSKVCCG 1020 YNVSETVHFA TTQWTSMGFE TAKEMKRRHI AKPFSMEKLL YQIAQAEAKK ENGPTLSTIS 1080 ALLDELRDTE LRQRRQLFEA GLHSSARYGS HDGSSAVADG KKKPRKWLQL ETSERRCQIC 1140 QHLCYLSMVV QENENVVFCL ECALRHVEKQ KSCRGLKLMY RYDEEQIISL VNQICGKVSG 1200 KHGGIENCLN KPTPKRGPRK RATVDVPPSR LPSS 1234 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | JARID2 | 478729 | A0A5F4DE24 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | JARID2 | 102184681 | A0A452DTS6 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | JARID2 | 3720 | Q92833 | CPO,CL/P | Homo sapiens | Publication | More>> | |
| 1:1 ortholog | Jarid2 | G3UZT8 | E14.5, E15.5 | Mus musculus | Prediction | More>> | ||
| 1:1 ortholog | JARID2 | 462450 | A0A2I3SRS8 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | JARID2 | A0A287AMW5 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | Jarid2 | 681740 | M0RBV7 | Rattus norvegicus | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0035098 | ESC/E(Z) complex |
| GO:0035097 | histone methyltransferase complex |
| GO:0005739 | mitochondrion |
| GO:0005634 | nucleus |
| GO:0003682 | chromatin binding |
| GO:0003677 | DNA binding |
| GO:0001227 | DNA-binding transcription repressor activity, RNA polymerase II-specific |
| GO:0032452 | histone demethylase activity |
| GO:0000977 | RNA polymerase II regulatory region sequence-specific DNA binding |
| GO:0008134 | transcription factor binding |
| GO:1990830 | cellular response to leukemia inhibitory factor |
| GO:0006338 | chromatin remodeling |
| GO:0034721 | histone H3-K4 demethylation, trimethyl-H3-K4-specific |
| GO:0001889 | liver development |
| GO:0060044 | negative regulation of cardiac muscle cell proliferation |
| GO:0010614 | negative regulation of cardiac muscle hypertrophy |
| GO:0008285 | negative regulation of cell population proliferation |
| GO:0031061 | negative regulation of histone methylation |
| GO:0000122 | negative regulation of transcription by RNA polymerase II |
| GO:0045892 | negative regulation of transcription, DNA-templated |
| GO:0051574 | positive regulation of histone H3-K9 methylation |
| GO:0042127 | regulation of cell population proliferation |
| GO:0048536 | spleen development |
| GO:0048863 | stem cell differentiation |
| GO:0048538 | thymus development |